HitPredict

Interactor 1: MLC2 (P54357)
Myosin-2 essential light chain (Myosin II essential light chain) (Non-muscle myosin essential light chain)
Gene: Mlc-c

Interactor 2: ASP (Q9VC45)
Protein abnormal spindle
Gene: ASP

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	16917818
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	EF-hand_6~IQ, EF-hand_7~IQ
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 147 Dm			1 1954
+	Ce
		195339 CALM_CAEEL (3-146): 5.11e-46: 148: 44.22		O17666_CAEEL (614-1527): 5.01e-102: 359: 14.46
+	Gg
		387172 MYL6_CHICK (1-147): 9.12e-55: 170: 54.31		MYH11_CHICK (969-1913): 5.27e-25: 116: 9.02
+	Hs
		516591 CALM3_HUMAN (3-146): 1.36e-46: 149: 44.90		MYO5C_HUMAN (1277-1910): 2.28e-28: 127: 13.82
+	Hs
		157155 MYL6_HUMAN (1-147): 4.17e-56: 174: 53.64		CTRO_HUMAN (830-1605): 1.15e-18: 95.8: 10.12
+	Hs
		73991 MYL6B_HUMAN (3-146): 1.31e-48: 156: 53.38		MYO9A_HUMAN (1177-1790): 6.12e-24: 113: 13.71
+	Hs
		776792 MYL6_HUMAN (1-147): 4.17e-56: 174: 53.64		MYH11_HUMAN (833-1735): 7.39e-16: 86.5: 9.87
+	Sc
		449063 CALM_YEAST (2-146): 8.31e-47: 150: 37.42		MYO2_YEAST (1150-1729): 2.09e-22: 108: 11.21
+	Hs
		156909 MYL6B_HUMAN (3-146): 1.31e-48: 156: 53.38		CTRO_HUMAN (830-1605): 1.15e-18: 95.8: 10.12
+	Hs
		516359 CALM1_HUMAN (3-146): 1.36e-46: 149: 44.90		ASPM_HUMAN (922-1805): 7.59e-19: 96.5: 15.57
+	Hs
		516431 CALM2_HUMAN (3-146): 1.36e-46: 149: 44.90		ASPM_HUMAN (922-1805): 7.59e-19: 96.5: 15.57
+	Hs
		516555 CALM3_HUMAN (3-146): 1.36e-46: 149: 44.90		ASPM_HUMAN (922-1805): 7.59e-19: 96.5: 15.57
+	Dm
		52512 CALM_DROME (3-146): 5.28e-46: 148: 44.90		A1Z6Z9_DROME (1341-1771): 3.66e-19: 97.3: 13.92
+	Hs
		952552 MYL6_HUMAN (1-147): 4.17e-56: 174: 53.64		MYO9B_HUMAN (1033-1175): 4.8e-11: 70.6: 23.29
+	Hs
		516603 CALM3_HUMAN (3-146): 1.36e-46: 149: 44.90		MYO5B_HUMAN (1275-1934): 6.44e-14: 79.9: 8.26
+	Hs
		573952 MYL6B_HUMAN (3-146): 1.31e-48: 156: 53.38		MYO9B_HUMAN (1033-1175): 4.8e-11: 70.6: 23.29
+	Hs
		516334 CALM1_HUMAN (3-146): 1.36e-46: 149: 44.90		MYO9B_HUMAN (1033-1175): 4.8e-11: 70.6: 23.29
+	Hs
		516408 CALM2_HUMAN (3-146): 1.36e-46: 149: 44.90		MYO9B_HUMAN (1033-1175): 4.8e-11: 70.6: 23.29
+	Hs
		516510 CALM3_HUMAN (3-146): 1.36e-46: 149: 44.90		MYO9B_HUMAN (1033-1175): 4.8e-11: 70.6: 23.29
+	Hs
		227774 CALM1_HUMAN (3-146): 1.36e-46: 149: 44.90		MYO1B_HUMAN (949-1141): 6.2e-11: 69.9: 18.87
+	Hs
		227775 CALM3_HUMAN (3-146): 1.36e-46: 149: 44.90		MYO1B_HUMAN (949-1141): 6.2e-11: 69.9: 18.87