HitPredict

Interactor 1: EPHA5 (P54756)
Ephrin type-A receptor 5 (EC 2.7.10.1) (Brain-specific kinase) (EPH homology kinase 1) (EHK-1) (EPH-like kinase 7) (EK7) (hEK7)
Gene: EPHA5

Interactor 2: GAB1 (Q13480)
GRB2-associated-binding protein 1 (GRB2-associated binder 1) (Growth factor receptor bound protein 2-associated protein 1)
Gene: GAB1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~PK_Tyr_Ser-Thr
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1037 Hs			1 694
+	Hs
		932066 EPHA4_HUMAN (33-1035): 0: 1165: 62.90		GAB1_HUMAN (1-694): 6.33e-173: 512: 100.00
+	Hs
		710827 EPHB2_HUMAN (60-1034): 0: 1159: 55.98		GAB1_HUMAN (1-694): 6.33e-173: 512: 100.00
+	Hs
		710225 EPHA2_HUMAN (58-1037): 0: 1054: 50.86		GAB1_HUMAN (1-694): 6.33e-173: 512: 100.00
+	Hs
		931900 EPHA5_HUMAN (1-1037): 0: 1316: 100.00		PKHA5_HUMAN (5-476): 3.42e-64: 232: 12.37
+	Hs
		931901 EPHA5_HUMAN (1-1037): 0: 1316: 100.00		PKHA1_HUMAN (6-156): 1.01e-32: 132: 25.49
+	Hs
		1147436 EPHA7_HUMAN (37-1035): 0: 1166: 61.90		PKHA5_HUMAN (5-476): 3.42e-64: 232: 12.37
+	Hs
		710894 EPHB2_HUMAN (60-1034): 0: 1159: 55.98		PKHA5_HUMAN (5-476): 3.42e-64: 232: 12.37
+	Hs
		1147463 EPHA7_HUMAN (37-1035): 0: 1166: 61.90		ATS7_HUMAN (247-653): 9.96e-53: 199: 15.04
+	Hs
		1147437 EPHA7_HUMAN (37-1035): 0: 1166: 61.90		PKHA1_HUMAN (6-156): 1.01e-32: 132: 25.49
+	Hs
		932137 EPHA4_HUMAN (33-1035): 0: 1165: 62.90		PKHA1_HUMAN (6-156): 1.01e-32: 132: 25.49
+	Hs
		710895 EPHB2_HUMAN (60-1034): 0: 1159: 55.98		PKHA1_HUMAN (6-156): 1.01e-32: 132: 25.49
+	Hs
		710499 EPHA2_HUMAN (58-1037): 0: 1054: 50.86		PKHA5_HUMAN (5-476): 3.42e-64: 232: 12.37
+	Hs
		710305 EPHA2_HUMAN (58-1037): 0: 1054: 50.86		PKHA7_HUMAN (5-485): 2.19e-62: 227: 11.88
+	Hs
		710581 EPHA2_HUMAN (58-1037): 0: 1054: 50.86		PKHA6_HUMAN (5-519): 6.22e-48: 184: 14.15
+	Hs
		710500 EPHA2_HUMAN (58-1037): 0: 1054: 50.86		PKHA2_HUMAN (2-194): 4.15e-35: 140: 20.77
+	Hs
		640292 EPHA1_HUMAN (47-1028): 0: 946: 41.68		PKHA5_HUMAN (5-476): 3.42e-64: 232: 12.37
+	Hs
		181825 EPHB6_HUMAN (43-1023): 0: 905: 38.33		PKHA5_HUMAN (5-476): 3.42e-64: 232: 12.37
+	Hs
		640336 EPHA1_HUMAN (47-1028): 0: 946: 41.68		PKHA6_HUMAN (5-519): 6.22e-48: 184: 14.15
+	Hs
		181826 EPHB6_HUMAN (43-1023): 0: 905: 38.33		PKHA1_HUMAN (6-156): 1.01e-32: 132: 25.49
+	Hs
		720211 UFO_HUMAN (293-954): 3.15e-152: 476: 23.37		GAB1_HUMAN (1-694): 6.33e-173: 512: 100.00