HitPredict

Interactor 1: TPM4 (P67936)
Tropomyosin alpha-4 chain (TM30p1) (Tropomyosin-4)
Gene: TPM4

Interactor 2: KLF12 (Q9Y4X4)
Krueppel-like factor 12 (Transcriptional repressor AP-2rep)
Gene: KLF12

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	35140242
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 248 Hs			1 402
+	Hs
		418926 TPM3_HUMAN (4-248): 6.47e-47: 159: 69.39		KLF3_HUMAN (20-402): 3.5e-72: 231: 38.48
+	Hs
		884127 TPM4_HUMAN (1-248): 5.49e-47: 158: 100.00		KLF3_HUMAN (20-402): 3.5e-72: 231: 38.48
+	Hs
		434445 TPM2_HUMAN (4-248): 5.04e-42: 146: 69.39		ZN229_HUMAN (2-296): 6.09e-63: 217: 5.92
+	Hs
		932043 TPM4_HUMAN (1-248): 5.49e-47: 158: 100.00		KLF6_HUMAN (308-400): 3.24e-48: 167: 79.57
+	Hs
		418949 TPM3_HUMAN (4-248): 6.47e-47: 159: 69.39		KLF10_HUMAN (246-400): 6.05e-28: 116: 44.52
+	Hs
		931998 TPM4_HUMAN (1-248): 5.49e-47: 158: 100.00		KLF10_HUMAN (246-400): 6.05e-28: 116: 44.52
+	Hs
		434905 TPM1_HUMAN (4-248): 1.43e-48: 163: 68.16		SP1_HUMAN (308-399): 8.44e-25: 108: 54.35
+	Hs
		418846 TPM3_HUMAN (4-248): 6.47e-47: 159: 69.39		SP1_HUMAN (308-399): 8.44e-25: 108: 54.35
+	Hs
		435035 TPM4_HUMAN (1-248): 5.49e-47: 158: 100.00		SP1_HUMAN (308-399): 8.44e-25: 108: 54.35
+	Hs
		434328 TPM2_HUMAN (4-248): 5.04e-42: 146: 69.39		SP1_HUMAN (308-399): 8.44e-25: 108: 54.35
+	Hs
		418952 TPM3_HUMAN (4-248): 6.47e-47: 159: 69.39		KLF9_HUMAN (336-399): 6.93e-09: 58.2: 45.46