HitPredict

Interactor 1: CCL8 (P80075)
C-C motif chemokine 8 (HC14) (Monocyte chemoattractant protein 2) (Monocyte chemotactic protein 2) (MCP-2) (Small-inducible cytokine A8) [Cleaved into: MCP-2(6-76)]
Gene: CCL8

Interactor 2: CXCL6 (P80162)
C-X-C motif chemokine 6 (Chemokine alpha 3) (CKA-3) (Granulocyte chemotactic protein 2) (GCP-2) (Small-inducible cytokine B6) [Cleaved into: Small-inducible cytokine B6, N-processed variant 1; Small-inducible cytokine B6, N-processed variant 2; Small-inducible cytokine B6, N-processed variant 3]
Gene: CXCL6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.692

The method score is based on:

Property Details
Experiments 28381538
Identification Methods pull down, filter binding
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains IL8~IL8
Common GO terms GO:0005615 - extracellular space
GO:0006935 - chemotaxis
GO:0006954 - inflammatory response
GO:0007165 - signal transduction
GO:0007267 - cell-cell signaling
and 4 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 99
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024