HitPredict

Interactor 1: RAB5B (P61020)
Ras-related protein Rab-5B (EC 3.6.5.2)
Gene: RAB5B

Interactor 2: VAMP3 (Q15836)
Vesicle-associated membrane protein 3 (VAMP-3) (Cellubrevin) (CEB) (Synaptobrevin-3)
Gene: VAMP3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	40437099
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane GO:0031901 - early endosome membrane GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 215 Hs			1 100
+	Hs
		981286 RAB1A_HUMAN (10-213): 9.39e-88: 258: 39.51		VAMP3_HUMAN (1-81): 5.93e-26: 93.9: 100.00
+	Sc
		376268 YPT1_YEAST (14-213): 1.04e-89: 263: 41.46		SEC22_YEAST (1-97): 4.41e-22: 87.3: 18.56
+	Hs
		278476 RAB5A_HUMAN (1-215): 1.29e-86: 256: 81.86		VAMP4_HUMAN (3-82): 2.08e-25: 93.9: 40.00
+	Hs
		631243 RAB5A_HUMAN (1-215): 1.29e-86: 256: 81.86		VAMP3_HUMAN (1-81): 5.93e-26: 93.9: 100.00
+	Hs
		1154737 RAB1B_HUMAN (13-213): 2.31e-86: 255: 39.30		VAMP3_HUMAN (1-81): 5.93e-26: 93.9: 100.00
+	Hs
		278482 RAB5C_HUMAN (1-215): 7.76e-86: 254: 84.26		VAMP4_HUMAN (3-82): 2.08e-25: 93.9: 40.00
+	Hs
		900834 RAB5C_HUMAN (1-215): 7.76e-86: 254: 84.26		VAMP3_HUMAN (1-81): 5.93e-26: 93.9: 100.00
+	Hs
		631132 RAB5A_HUMAN (1-215): 1.29e-86: 256: 81.86		VAMP7_HUMAN (7-79): 2.14e-23: 90.8: 31.51
+	Hs
		955934 RAB8A_HUMAN (14-211): 3.46e-85: 252: 34.85		VAMP3_HUMAN (1-81): 5.93e-26: 93.9: 100.00
+	Hs
		900735 RAB5C_HUMAN (1-215): 7.76e-86: 254: 84.26		VAMP7_HUMAN (7-79): 2.14e-23: 90.8: 31.51
+	Hs
		631157 RAB5A_HUMAN (1-215): 1.29e-86: 256: 81.86		VAMP2_HUMAN (8-84): 9.13e-23: 86.6: 87.01
+	Hs
		278488 RB11A_HUMAN (10-215): 1.7e-83: 248: 38.61		VAMP4_HUMAN (3-82): 2.08e-25: 93.9: 40.00
+	Hs
		976291 RB11A_HUMAN (10-215): 1.7e-83: 248: 38.61		VAMP3_HUMAN (1-81): 5.93e-26: 93.9: 100.00
+	Hs
		631445 RAB5A_HUMAN (1-215): 1.29e-86: 256: 81.86		VAMP8_HUMAN (6-82): 1.06e-22: 85.8: 35.07
+	Hs
		900764 RAB5C_HUMAN (1-215): 7.76e-86: 254: 84.26		VAMP2_HUMAN (8-84): 9.13e-23: 86.6: 87.01
+	Hs
		901013 RAB5C_HUMAN (1-215): 7.76e-86: 254: 84.26		VAMP8_HUMAN (6-82): 1.06e-22: 85.8: 35.07
+	Hs
		278486 RAB2A_HUMAN (17-208): 3.63e-82: 245: 37.50		VAMP4_HUMAN (3-82): 2.08e-25: 93.9: 40.00
+	Hs
		907998 RB11A_HUMAN (10-215): 1.7e-83: 248: 38.61		VAMP7_HUMAN (7-79): 2.14e-23: 90.8: 31.51
+	Hs
		976192 RB11A_HUMAN (10-215): 1.7e-83: 248: 38.61		VAMP2_HUMAN (8-84): 9.13e-23: 86.6: 87.01
+	Hs
		976525 RB11A_HUMAN (10-215): 1.7e-83: 248: 38.61		VAMP8_HUMAN (6-82): 1.06e-22: 85.8: 35.07