HitPredict

Interactor 1: KALRN (P97924)
Kalirin (EC 2.7.11.1) (Huntingtin-associated protein-interacting protein) (PAM COOH-terminal interactor protein 10) (P-CIP10) (Protein Duo) (Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain)
Gene: KALRN

Interactor 2: NMDE1 (Q00959)
Glutamate receptor ionotropic, NMDA 2A (GluN2A) (Glutamate [NMDA] receptor subunit epsilon-1) (N-methyl D-aspartate receptor subtype 2A) (NMDAR2A) (NR2A)
Gene: Grin2a

Species: Rattus norvegicus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	31801062
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0007613 - memory GO:0014069 - postsynaptic density GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2959 Rn			1 1464
+	Rn
		957072 KALRN_RAT (1-2959): 0: 2285: 100.00		NMDE2_RAT (4-1464): 0: 1522: 52.85
+	Mm
		57819 KALRN_MOUSE (1-2959): 0: 2278: 99.02		G3X9V4_MOUSE (4-1464): 0: 1515: 52.78
+	Mm
		57838 KALRN_MOUSE (1-2959): 0: 2278: 99.02		NMDE2_MOUSE (4-1464): 0: 1514: 52.72
+	Rn
		585146 KALRN_RAT (1-2959): 0: 2285: 100.00		GRIA1_RAT (13-912): 0: 695: 19.50
+	Hs
		224704 KALRN_HUMAN (5-2959): 0: 2255: 97.54		GRIK1_HUMAN (2-847): 0: 711: 19.34
+	Mm
		57882 KALRN_MOUSE (1-2959): 0: 2278: 99.02		GRIA3_MOUSE (11-870): 0: 680: 18.50
+	Mm
		57832 KALRN_MOUSE (1-2959): 0: 2278: 99.02		NMDZ1_MOUSE (8-940): 0: 678: 23.05
+	Mm
		57829 KALRN_MOUSE (1-2959): 0: 2278: 99.02		GRIA2_MOUSE (11-870): 0: 657: 17.71
+	Mm
		57814 KALRN_MOUSE (1-2959): 0: 2278: 99.02		F2Z488_MOUSE (11-810): 0: 635: 18.48
+	Hs
		1018891 SPTN1_HUMAN (41-1719): 1.09e-87: 323: 12.37		NMDE1_HUMAN (1-1464): 0: 1692: 95.22
+	Hs
		1028137 SPTN1_HUMAN (41-1719): 1.09e-87: 323: 12.37		NMDE2_HUMAN (4-1464): 0: 1503: 52.65
+	Mm
		963749 DAPK1_MOUSE (2646-2915): 5.41e-61: 234: 40.65		NMDE2_MOUSE (4-1464): 0: 1514: 52.72
+	Hs
		984260 SPTN1_HUMAN (41-1719): 1.09e-87: 323: 12.37		NMDZ1_HUMAN (13-940): 0: 674: 23.07
+	Rn
		555251 SPTN1_RAT (41-1719): 2.52e-87: 322: 12.49		GRIA4_RAT (10-863): 0: 662: 18.82
+	Hs
		786733 SPTN1_HUMAN (41-1719): 1.09e-87: 323: 12.37		GRIA2_HUMAN (11-870): 0: 659: 18.08
+	Mm
		723587 SPTB2_MOUSE (3-1253): 3.78e-74: 279: 14.27		NMDZ1_MOUSE (8-940): 0: 678: 23.05
+	Hs
		786728 SPTB2_HUMAN (3-1253): 3.28e-73: 276: 14.42		GRIA2_HUMAN (11-870): 0: 659: 18.08
+	Mm
		723597 DAPK1_MOUSE (2646-2915): 5.41e-61: 234: 40.65		NMDZ1_MOUSE (8-940): 0: 678: 23.05
+	Hs
		200077 DAPK3_HUMAN (2650-2912): 2.39e-62: 223: 40.59		NMD3B_HUMAN (78-873): 0: 642: 25.95
+	Rn
		585221 SPTN2_RAT (33-905): 1.04e-47: 192: 14.61		GRIA4_RAT (10-863): 0: 662: 18.82