HitPredict

Interactor 1: DAB2 (P98078)
Disabled homolog 2 (Adaptor molecule disabled-2) (Differentially expressed in ovarian carcinoma 2) (DOC-2) (Mitogen-responsive phosphoprotein)
Gene: DAB2

Interactor 2: GRB2 (Q60631)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2)
Gene: GRB2

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	9569023
Identification Methods	anti bait coimmunoprecipitation, pull down
Interaction Type	association, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 766 Mm			1 217
+	Hs
		924477 DAB2_HUMAN (1-766): 8.87e-80: 273: 81.76		GRB2_HUMAN (1-217): 6.92e-74: 224: 99.54
+	Dm
		957161 DAB_DROME (1-758): 7.74e-52: 198: 19.64		GRAP_DROME (1-215): 5.25e-62: 193: 61.86
+	Hs
		924646 SHC4_HUMAN (2-337): 1.02e-41: 163: 12.37		GRB2_HUMAN (1-217): 6.92e-74: 224: 99.54
+	Mm
		957157 DAB2_MOUSE (1-766): 9.01e-96: 316: 100.00		ITSN1_MOUSE (160-216): 2.45e-11: 64.6: 33.33
+	Hs
		782772 DAB2_HUMAN (1-766): 8.87e-80: 273: 81.76		CSK_HUMAN (2-139): 4.25e-24: 100: 36.24
+	Hs
		557659 DAB2_HUMAN (1-766): 8.87e-80: 273: 81.76		NCK1_HUMAN (5-145): 9.45e-23: 96.3: 33.14
+	Hs
		412132 DAB2_HUMAN (1-766): 8.87e-80: 273: 81.76		FYN_HUMAN (161-215): 4.88e-13: 69.2: 31.58
+	Hs
		454823 DAB2_HUMAN (1-766): 8.87e-80: 273: 81.76		FGR_HUMAN (161-215): 5.31e-12: 66.1: 33.33
+	Hs
		957186 DAB2_HUMAN (1-766): 8.87e-80: 273: 81.76		ITSN1_HUMAN (160-216): 3.02e-11: 64.2: 33.33
+	Hs
		522909 DAB2_HUMAN (1-766): 8.87e-80: 273: 81.76		SRC_HUMAN (160-215): 1.74e-10: 61.9: 31.03
+	Hs
		411643 NUMB_HUMAN (26-678): 6e-47: 179: 14.24		LCK_HUMAN (3-202): 7.66e-38: 138: 28.91
+	Dm
		337651 DAB_DROME (1-758): 7.74e-52: 198: 19.64		ABL_DROME (4-135): 1.01e-22: 97.4: 37.68
+	Hs
		253523 CAPON_HUMAN (21-284): 6.11e-38: 150: 14.53		LCK_HUMAN (3-202): 7.66e-38: 138: 28.91
+	Hs
		269120 DAB1_HUMAN (11-617): 1.62e-37: 150: 23.57		NCK1_HUMAN (5-145): 9.45e-23: 96.3: 33.14
+	Hs
		433649 NUMB_HUMAN (26-678): 6e-47: 179: 14.24		LYN_HUMAN (136-215): 4.12e-10: 60.7: 24.39
+	Mm
		1206702 ANS1B_MOUSE (2-231): 5.14e-41: 164: 17.95		ITSN1_MOUSE (160-216): 2.45e-11: 64.6: 33.33
+	Hs
		253524 CAPON_HUMAN (21-284): 6.11e-38: 150: 14.53		FYN_HUMAN (161-215): 4.88e-13: 69.2: 31.58
+	Mm
		763385 DAB1_MOUSE (11-617): 3.62e-37: 149: 24.35		FYN_MOUSE (161-215): 4.88e-13: 69.2: 31.58
+	Hs
		269148 DAB1_HUMAN (11-617): 1.62e-37: 150: 23.57		ITSN1_HUMAN (160-216): 3.02e-11: 64.2: 33.33
+	Mm
		403429 DAB1_MOUSE (11-617): 3.62e-37: 149: 24.35		SRC_MOUSE (80-215): 1.5e-10: 61.9: 17.24