HitPredict

Interactor 1: CSN2 (P61201)
COP9 signalosome complex subunit 2 (SGN2) (Signalosome subunit 2) (Alien homolog) (JAB1-containing signalosome subunit 2) (Thyroid receptor-interacting protein 15) (TR-interacting protein 15) (TRIP-15)
Gene: COPS2

Interactor 2: KLH10 (Q6JEL2)
Kelch-like protein 10
Gene: KLHL10

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.60	0.662

Property	Details
Experiments	28514442, 33961781, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 443 Hs			1 608
+	Hs
		958649 CSN2_HUMAN (1-443): 3.16e-127: 377: 100.00		KLH12_HUMAN (19-575): 9.32e-160: 471: 32.14
+	Hs
		958726 CSN2_HUMAN (1-443): 3.16e-127: 377: 100.00		KLHL8_HUMAN (5-574): 8.09e-150: 447: 28.37
+	Hs
		1094354 CSN1_HUMAN (17-443): 7.06e-80: 257: 15.02		KLH10_HUMAN (1-608): 5.19e-176: 514: 100.00
+	Hs
		1235386 CSN4_HUMAN (54-440): 8.18e-74: 238: 16.25		KLH10_HUMAN (1-608): 5.19e-176: 514: 100.00
+	Hs
		1094345 CSN1_HUMAN (17-443): 7.06e-80: 257: 15.02		KLH12_HUMAN (19-575): 9.32e-160: 471: 32.14
+	Hs
		1199027 CSN4_HUMAN (54-440): 8.18e-74: 238: 16.25		KLH12_HUMAN (19-575): 9.32e-160: 471: 32.14
+	Hs
		1094431 CSN1_HUMAN (17-443): 7.06e-80: 257: 15.02		KLHL8_HUMAN (5-574): 8.09e-150: 447: 28.37
+	Hs
		958728 CSN2_HUMAN (1-443): 3.16e-127: 377: 100.00		KLH13_HUMAN (387-607): 6.73e-52: 190: 21.93
+	Hs
		320819 CSN2_HUMAN (1-443): 3.16e-127: 377: 100.00		KLH18_HUMAN (461-608): 3.9e-34: 138: 28.00
+	Hs
		958710 CSN2_HUMAN (1-443): 3.16e-127: 377: 100.00		KLHL4_HUMAN (260-432): 3.33e-27: 118: 26.09
+	Hs
		958660 CSN2_HUMAN (1-443): 3.16e-127: 377: 100.00		KLH24_HUMAN (465-607): 2.08e-20: 97.2: 19.05
+	Hs
		1094432 CSN1_HUMAN (17-443): 7.06e-80: 257: 15.02		KLHL9_HUMAN (387-607): 1.04e-52: 192: 22.81
+	Hs
		1094434 CSN1_HUMAN (17-443): 7.06e-80: 257: 15.02		KLH13_HUMAN (387-607): 6.73e-52: 190: 21.93
+	Hs
		1094370 CSN1_HUMAN (17-443): 7.06e-80: 257: 15.02		KLH36_HUMAN (370-607): 2.97e-45: 171: 19.68
+	Hs
		1413211 CSN4_HUMAN (54-440): 8.18e-74: 238: 16.25		KLH13_HUMAN (387-607): 6.73e-52: 190: 21.93
+	Hs
		320821 CSN1_HUMAN (17-443): 7.06e-80: 257: 15.02		KLH18_HUMAN (461-608): 3.9e-34: 138: 28.00
+	Hs
		320839 CSN4_HUMAN (54-440): 8.18e-74: 238: 16.25		KLH18_HUMAN (461-608): 3.9e-34: 138: 28.00
+	Hs
		1094414 CSN1_HUMAN (17-443): 7.06e-80: 257: 15.02		KLHL4_HUMAN (260-432): 3.33e-27: 118: 26.09
+	Hs
		1094355 CSN1_HUMAN (17-443): 7.06e-80: 257: 15.02		KLH24_HUMAN (465-607): 2.08e-20: 97.2: 19.05