HitPredict

Interactor 1: CSN2 (P61201)
COP9 signalosome complex subunit 2 (SGN2) (Signalosome subunit 2) (Alien homolog) (JAB1-containing signalosome subunit 2) (Thyroid receptor-interacting protein 15) (TR-interacting protein 15) (TRIP-15)
Gene: COPS2

Interactor 2: KLH13 (Q9P2N7)
Kelch-like protein 13 (BTB and kelch domain-containing protein 2)
Gene: KLHL13

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.643

Property	Details
Experiments	19615732, 21145461, unassigned3799
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 443 Hs			1 655
+	Hs
		1094434 CSN1_HUMAN (17-443): 7.06e-80: 257: 15.02		KLH13_HUMAN (1-655): 0: 599: 100.00
+	Hs
		958650 CSN2_HUMAN (1-443): 3.16e-127: 377: 100.00		KLH22_HUMAN (38-651): 1.25e-147: 444: 32.38
+	Hs
		958657 CSN2_HUMAN (1-443): 3.16e-127: 377: 100.00		KLH10_HUMAN (80-651): 1.16e-144: 435: 26.60
+	Hs
		1094432 CSN1_HUMAN (17-443): 7.06e-80: 257: 15.02		KLHL9_HUMAN (44-655): 0: 548: 92.81
+	Hs
		1094354 CSN1_HUMAN (17-443): 7.06e-80: 257: 15.02		KLH10_HUMAN (80-651): 1.16e-144: 435: 26.60
+	Hs
		1235386 CSN4_HUMAN (54-440): 8.18e-74: 238: 16.25		KLH10_HUMAN (80-651): 1.16e-144: 435: 26.60
+	Hs
		958726 CSN2_HUMAN (1-443): 3.16e-127: 377: 100.00		KLHL8_HUMAN (441-653): 1.01e-48: 182: 28.04
+	Hs
		958660 CSN2_HUMAN (1-443): 3.16e-127: 377: 100.00		KLH24_HUMAN (405-647): 7.27e-40: 156: 21.95
+	Hs
		320819 CSN2_HUMAN (1-443): 3.16e-127: 377: 100.00		KLH18_HUMAN (469-648): 2.89e-39: 154: 23.08
+	Hs
		958710 CSN2_HUMAN (1-443): 3.16e-127: 377: 100.00		KLHL4_HUMAN (472-649): 1.04e-34: 142: 20.23
+	Hs
		958649 CSN2_HUMAN (1-443): 3.16e-127: 377: 100.00		KLH12_HUMAN (522-650): 3.88e-19: 93.4: 23.49
+	Hs
		958697 CSN2_HUMAN (1-443): 3.16e-127: 377: 100.00		KLH15_HUMAN (492-647): 1.04e-17: 89.1: 17.31
+	Hs
		1094431 CSN1_HUMAN (17-443): 7.06e-80: 257: 15.02		KLHL8_HUMAN (441-653): 1.01e-48: 182: 28.04
+	Hs
		1094355 CSN1_HUMAN (17-443): 7.06e-80: 257: 15.02		KLH24_HUMAN (405-647): 7.27e-40: 156: 21.95
+	Hs
		1094370 CSN1_HUMAN (17-443): 7.06e-80: 257: 15.02		KLH36_HUMAN (425-646): 3.07e-39: 154: 21.30
+	Hs
		320821 CSN1_HUMAN (17-443): 7.06e-80: 257: 15.02		KLH18_HUMAN (469-648): 2.89e-39: 154: 23.08
+	Hs
		1094414 CSN1_HUMAN (17-443): 7.06e-80: 257: 15.02		KLHL4_HUMAN (472-649): 1.04e-34: 142: 20.23
+	Hs
		320839 CSN4_HUMAN (54-440): 8.18e-74: 238: 16.25		KLH18_HUMAN (469-648): 2.89e-39: 154: 23.08
+	Hs
		1094345 CSN1_HUMAN (17-443): 7.06e-80: 257: 15.02		KLH12_HUMAN (522-650): 3.88e-19: 93.4: 23.49
+	Hs
		1199027 CSN4_HUMAN (54-440): 8.18e-74: 238: 16.25		KLH12_HUMAN (522-650): 3.88e-19: 93.4: 23.49