HitPredict

Interactor 1: DCAF7 (P61962)
DDB1- and CUL4-associated factor 7 (WD repeat-containing protein 68) (WD repeat-containing protein An11 homolog)
Gene: DCAF7

Interactor 2: PCGF3 (Q3KNV8)
Polycomb group RING finger protein 3 (RING finger protein 3A)
Gene: PCGF3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.60	0.716

Property	Details
Experiments	27705803, 28514442, 24981860, 33961781, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 342 Hs			1 242
+	Hs
		766077 DCAF7_HUMAN (1-342): 2.52e-86: 265: 100.00		PCGF2_HUMAN (3-238): 3.05e-58: 189: 33.76
+	Hs
		964729 DCAF7_HUMAN (1-342): 2.52e-86: 265: 100.00		PCGF1_HUMAN (3-238): 3.33e-45: 153: 39.17
+	Hs
		964732 DCAF7_HUMAN (1-342): 2.52e-86: 265: 100.00		PCGF6_HUMAN (3-235): 5.41e-43: 150: 34.89
+	Hs
		964661 DCAF7_HUMAN (1-342): 2.52e-86: 265: 100.00		PCGF5_HUMAN (4-241): 1.49e-39: 138: 38.06
+	Hs
		964720 DCAF7_HUMAN (1-342): 2.52e-86: 265: 100.00		RING2_HUMAN (2-237): 1e-35: 131: 18.00
+	Mm
		964796 DCAF7_MOUSE (1-342): 2.52e-86: 265: 100.00		RING2_MOUSE (2-237): 7.77e-36: 131: 18.00
+	Hs
		964589 DCAF7_HUMAN (1-342): 2.52e-86: 265: 100.00		RING1_HUMAN (3-172): 7.36e-35: 130: 20.81
+	Mm
		1283483 Q80ZU1_MOUSE (1-342): 1.29e-84: 260: 99.71		RING2_MOUSE (2-237): 7.77e-36: 131: 18.00
+	Hs
		964783 DCAF7_HUMAN (1-342): 2.52e-86: 265: 100.00		TRI17_HUMAN (2-228): 5.88e-33: 126: 15.35
+	Hs
		765867 WDR33_HUMAN (7-204): 2.63e-31: 126: 10.61		BMI1_HUMAN (3-238): 8.59e-60: 193: 33.76
+	Dm
		1377801 EBI_DROME (103-342): 1.76e-39: 149: 15.92		Q9VV77_DROME (2-241): 1.13e-49: 163: 54.55
+	Hs
		765316 WDR5_HUMAN (208-342): 1.41e-28: 114: 11.85		BMI1_HUMAN (3-238): 8.59e-60: 193: 33.76
+	Hs
		965215 WDR5_HUMAN (208-342): 1.41e-28: 114: 11.85		PCGF6_HUMAN (3-235): 5.41e-43: 150: 34.89
+	Mm
		1296652 TBL1R_MOUSE (66-254): 1.19e-28: 117: 18.59		RING2_MOUSE (2-237): 7.77e-36: 131: 18.00
+	Hs
		965178 WDR5_HUMAN (208-342): 1.41e-28: 114: 11.85		RING2_HUMAN (2-237): 1e-35: 131: 18.00
+	Mm
		965403 WDR5_MOUSE (208-342): 1.41e-28: 114: 11.85		RING2_MOUSE (2-237): 7.77e-36: 131: 18.00
+	Hs
		964879 WDR5_HUMAN (208-342): 1.41e-28: 114: 11.85		RING1_HUMAN (3-172): 7.36e-35: 130: 20.81
+	Hs
		1390286 GRWD1_HUMAN (125-326): 1.98e-23: 102: 22.62		TRI11_HUMAN (2-191): 5.2e-32: 123: 14.36
+	Mm
		1222104 RBBP7_MOUSE (2-153): 4.28e-15: 77.5: 15.72		RING2_MOUSE (2-237): 7.77e-36: 131: 18.00
+	Mm
		1222081 RBBP4_MOUSE (5-153): 1.14e-14: 76.4: 14.74		RING2_MOUSE (2-237): 7.77e-36: 131: 18.00