HitPredict

Interactor 1: HNRPK (P61980)
Heterogeneous nuclear ribonucleoprotein K (hnRNP K) (dC stretch-binding protein) (CSBP)
Gene: Hnrnpk

Interactor 2: GRB2 (P62994)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2

Species: Rattus norvegicus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	16518874
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005938 - cell cortex GO:0019904 - protein domain specific binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 463 Rn			1 217
+	Mm
		966008 HNRPK_MOUSE (1-463): 3.38e-139: 409: 100.00		GRB2_MOUSE (1-217): 5.96e-71: 217: 99.54
+	Hs
		965609 HNRPK_HUMAN (1-463): 3.38e-139: 409: 100.00		GRB2_HUMAN (1-217): 1.28e-70: 216: 100.00
+	Hs
		834163 HNRPK_HUMAN (1-463): 3.38e-139: 409: 100.00		CSK_HUMAN (2-139): 3.94e-24: 100: 36.24
+	Mm
		699349 HNRPK_MOUSE (1-463): 3.38e-139: 409: 100.00		VAV_MOUSE (2-60): 5.61e-14: 71.9: 42.37
+	Hs
		584507 HNRPK_HUMAN (1-463): 3.38e-139: 409: 100.00		VAV_HUMAN (2-60): 7.9e-14: 71.6: 42.37
+	Hs
		965923 HNRPK_HUMAN (1-463): 3.38e-139: 409: 100.00		ITSN2_HUMAN (108-216): 6.53e-13: 69.2: 18.92
+	Hs
		440474 HNRPK_HUMAN (1-463): 3.38e-139: 409: 100.00		FYN_HUMAN (161-215): 9.09e-13: 68.5: 31.58
+	Hs
		965695 HNRPK_HUMAN (1-463): 3.38e-139: 409: 100.00		ITSN1_HUMAN (122-216): 3.21e-11: 64.2: 23.53
+	Hs
		473396 HNRPK_HUMAN (1-463): 3.38e-139: 409: 100.00		HCK_HUMAN (92-215): 4.76e-11: 63.5: 18.90
+	Hs
		292821 HNRPK_HUMAN (1-463): 3.38e-139: 409: 100.00		GRAP2_HUMAN (3-55): 1.97e-10: 61.3: 39.62
+	Hs
		557198 HNRPK_HUMAN (1-463): 3.38e-139: 409: 100.00		SRC_HUMAN (161-215): 3.49e-10: 60.8: 31.58
+	Hs
		463435 HNRPK_HUMAN (1-463): 3.38e-139: 409: 100.00		LYN_HUMAN (129-215): 1.97e-09: 58.5: 22.47
+	Mm
		683091 HNRPK_MOUSE (1-463): 3.38e-139: 409: 100.00		LYN_MOUSE (96-215): 2.24e-09: 58.5: 18.03
+	Hs
		987986 IF2B1_HUMAN (1-461): 7.01e-66: 223: 14.71		GRB2_HUMAN (1-217): 1.28e-70: 216: 100.00
+	Hs
		463871 IF2B2_HUMAN (6-454): 1.29e-76: 252: 16.16		LYN_HUMAN (129-215): 1.97e-09: 58.5: 22.47
+	Hs
		987861 FUBP3_HUMAN (336-457): 3.82e-12: 70.4: 24.59		GRB2_HUMAN (1-217): 1.28e-70: 216: 100.00
+	Hs
		841010 PCBP1_HUMAN (7-111): 7.46e-12: 68.5: 14.95		FRK_HUMAN (4-139): 3.55e-23: 98.2: 38.00
+	Hs
		557318 PCBP2_HUMAN (127-222): 1.6e-12: 70.8: 29.17		SRC_HUMAN (161-215): 3.49e-10: 60.8: 31.58
+	Hs
		557194 PCBP3_HUMAN (2-111): 7.55e-12: 68.5: 16.67		SRC_HUMAN (161-215): 3.49e-10: 60.8: 31.58
+	Hs
		463706 FUBP3_HUMAN (336-457): 3.82e-12: 70.4: 24.59		LYN_HUMAN (129-215): 1.97e-09: 58.5: 22.47