HitPredict

Interactor 1: GRB2 (P62993)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2

Interactor 2: FUBP3 (Q96I24)
Far upstream element-binding protein 3 (FUSE-binding protein 3)
Gene: FUBP3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17474147
Identification Methods	peptide array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 217 Hs			1 572
+	Hs
		987828 GRB2_HUMAN (1-217): 1.28e-70: 216: 100.00		FUBP2_HUMAN (14-558): 1.84e-109: 345: 42.88
+	Hs
		463706 LYN_HUMAN (129-215): 1.97e-09: 58.5: 22.47		FUBP3_HUMAN (1-572): 4.54e-168: 491: 100.00
+	Hs
		987986 GRB2_HUMAN (1-217): 1.28e-70: 216: 100.00		IF2B1_HUMAN (237-560): 4.33e-25: 111: 15.69
+	Mm
		966008 GRB2_MOUSE (1-217): 5.96e-71: 217: 99.54		HNRPK_MOUSE (256-475): 7.89e-23: 103: 16.17
+	Hs
		965609 GRB2_HUMAN (1-217): 1.28e-70: 216: 100.00		HNRPK_HUMAN (256-475): 7.89e-23: 103: 16.17
+	Rn
		966131 GRB2_RAT (1-217): 1.28e-70: 216: 100.00		HNRPK_RAT (256-475): 7.89e-23: 103: 16.17
+	Hs
		834163 CSK_HUMAN (2-139): 3.94e-24: 100: 36.24		HNRPK_HUMAN (256-475): 7.89e-23: 103: 16.17
+	Hs
		841010 FRK_HUMAN (4-139): 3.55e-23: 98.2: 38.00		PCBP1_HUMAN (6-323): 9.14e-22: 98.9: 14.24
+	Mm
		699349 VAV_MOUSE (2-60): 5.61e-14: 71.9: 42.37		HNRPK_MOUSE (256-475): 7.89e-23: 103: 16.17
+	Hs
		584507 VAV_HUMAN (2-60): 7.9e-14: 71.6: 42.37		HNRPK_HUMAN (256-475): 7.89e-23: 103: 16.17
+	Hs
		965923 ITSN2_HUMAN (108-216): 6.53e-13: 69.2: 18.92		HNRPK_HUMAN (256-475): 7.89e-23: 103: 16.17
+	Hs
		440474 FYN_HUMAN (161-215): 9.09e-13: 68.5: 31.58		HNRPK_HUMAN (256-475): 7.89e-23: 103: 16.17
+	Hs
		965695 ITSN1_HUMAN (122-216): 3.21e-11: 64.2: 23.53		HNRPK_HUMAN (256-475): 7.89e-23: 103: 16.17
+	Hs
		473396 HCK_HUMAN (92-215): 4.76e-11: 63.5: 18.90		HNRPK_HUMAN (256-475): 7.89e-23: 103: 16.17
+	Hs
		292821 GRAP2_HUMAN (3-55): 1.97e-10: 61.3: 39.62		HNRPK_HUMAN (256-475): 7.89e-23: 103: 16.17
+	Hs
		557198 SRC_HUMAN (161-215): 3.49e-10: 60.8: 31.58		HNRPK_HUMAN (256-475): 7.89e-23: 103: 16.17
+	Hs
		557318 SRC_HUMAN (161-215): 3.49e-10: 60.8: 31.58		PCBP2_HUMAN (6-331): 1.03e-22: 101: 15.95
+	Hs
		463435 LYN_HUMAN (129-215): 1.97e-09: 58.5: 22.47		HNRPK_HUMAN (256-475): 7.89e-23: 103: 16.17
+	Mm
		683091 LYN_MOUSE (96-215): 2.24e-09: 58.5: 18.03		HNRPK_MOUSE (256-475): 7.89e-23: 103: 16.17
+	Hs
		557194 SRC_HUMAN (161-215): 3.49e-10: 60.8: 31.58		PCBP3_HUMAN (31-142): 2.76e-14: 76.5: 28.21