HitPredict

Interactor 1: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Interactor 2: M3K10 (Q02779)
Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST)
Gene: MAP3K10

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36931259
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	14-3-3~PK_Tyr_Ser-Thr
Common GO terms	GO:0005737 - cytoplasm GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 247 Hs			1 954
+	Hs
		971424 1433E_HUMAN (1-244): 2.03e-141: 398: 63.53		M3K10_HUMAN (1-954): 0: 723: 100.00
+	Hs
		971400 1433E_HUMAN (1-244): 2.03e-141: 398: 63.53		M3K9_HUMAN (16-951): 2.74e-175: 540: 51.67
+	Hs
		966191 1433G_HUMAN (1-247): 3.17e-139: 392: 100.00		M3K9_HUMAN (16-951): 2.74e-175: 540: 51.67
+	Hs
		971620 1433E_HUMAN (1-244): 2.03e-141: 398: 63.53		M3K21_HUMAN (20-952): 8.23e-167: 516: 45.00
+	Hs
		966440 1433G_HUMAN (1-247): 3.17e-139: 392: 100.00		M3K21_HUMAN (20-952): 8.23e-167: 516: 45.00
+	Hs
		971762 1433E_HUMAN (1-244): 2.03e-141: 398: 63.53		ULK2_HUMAN (97-884): 4.85e-132: 425: 18.53
+	Hs
		840942 1433E_HUMAN (1-244): 2.03e-141: 398: 63.53		ABL2_HUMAN (5-924): 7.56e-124: 406: 17.32
+	Hs
		362231 1433E_HUMAN (1-244): 2.03e-141: 398: 63.53		ABL1_HUMAN (5-952): 1.03e-123: 405: 17.68
+	Hs
		840941 1433G_HUMAN (1-247): 3.17e-139: 392: 100.00		ABL2_HUMAN (5-924): 7.56e-124: 406: 17.32
+	Hs
		362230 1433G_HUMAN (1-247): 3.17e-139: 392: 100.00		ABL1_HUMAN (5-952): 1.03e-123: 405: 17.68
+	At
		1030880 14332_ARATH (4-244): 1.4e-141: 398: 61.32		PBS1_ARATH (29-465): 1.28e-125: 390: 19.83
+	Hs
		362252 1433F_HUMAN (1-246): 2.51e-135: 382: 86.99		ABL1_HUMAN (5-952): 1.03e-123: 405: 17.68
+	Hs
		971777 1433E_HUMAN (1-244): 2.03e-141: 398: 63.53		MINK1_HUMAN (76-925): 6.32e-115: 385: 15.87
+	Hs
		972066 1433E_HUMAN (1-244): 2.03e-141: 398: 63.53		M3K20_HUMAN (89-873): 4.64e-119: 384: 21.85
+	Hs
		966607 1433G_HUMAN (1-247): 3.17e-139: 392: 100.00		MINK1_HUMAN (76-925): 6.32e-115: 385: 15.87
+	Hs
		966948 1433G_HUMAN (1-247): 3.17e-139: 392: 100.00		M3K20_HUMAN (89-873): 4.64e-119: 384: 21.85
+	At
		1030873 14332_ARATH (4-244): 1.4e-141: 398: 61.32		BAK1_ARATH (58-410): 3.31e-118: 376: 23.16
+	At
		840383 14333_ARATH (1-244): 4.42e-142: 400: 61.79		PBL9_ARATH (53-415): 5.24e-119: 371: 20.25
+	Hs
		213885 1433E_HUMAN (1-244): 2.03e-141: 398: 63.53		M3K7_HUMAN (83-355): 2.88e-45: 175: 38.49
+	Hs
		213908 1433F_HUMAN (1-246): 2.51e-135: 382: 86.99		M3K7_HUMAN (83-355): 2.88e-45: 175: 38.49