HitPredict

Interactor 1: E9PMD8 (E9PMD8)
Proteasome 26S subunit, ATPase 3
Gene: PSMC3

Interactor 2: PSB7 (Q99436)
Proteasome subunit beta type-7 (EC 3.4.25.1) (Macropain chain Z) (Multicatalytic endopeptidase complex chain Z) (Proteasome subunit Z) (Proteasome subunit beta-2) (beta-2)
Gene: PSMB7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.80	0.514

Property	Details
Experiments	35271311
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	AAA~Proteasome
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 301 Hs			1 277
+	Hs
		610445 PRS6A_HUMAN (20-301): 1.67e-75: 239: 95.47		PSB7_HUMAN (1-277): 5.23e-103: 302: 100.00
+	Hs
		778760 PRS7_HUMAN (14-300): 4.79e-70: 225: 31.36		PSB7_HUMAN (1-277): 5.23e-103: 302: 100.00
+	Dm
		875036 PRS4_DROME (51-301): 1.41e-87: 270: 40.00		Q9VUJ1_DROME (10-277): 7.79e-84: 253: 64.82
+	Dm
		874988 PRS4_DROME (51-301): 1.41e-87: 270: 40.00		PSA5_DROME (13-242): 4.84e-81: 245: 17.48
+	Dm
		874969 PRS4_DROME (51-301): 1.41e-87: 270: 40.00		Q7K148_DROME (5-251): 4.62e-77: 237: 26.91
+	Hs
		97063 E9PMD8_HUMAN (1-301): 1.06e-81: 250: 100.00		PSA5_HUMAN (13-241): 1.34e-82: 249: 18.52
+	Dm
		47754 PRS4_DROME (51-301): 1.41e-87: 270: 40.00		A0AQH0_DROME (41-247): 5.44e-72: 222: 26.92
+	Hs
		610234 PRS6A_HUMAN (20-301): 1.67e-75: 239: 95.47		PSA5_HUMAN (13-241): 1.34e-82: 249: 18.52
+	Hs
		97059 E9PMD8_HUMAN (1-301): 1.06e-81: 250: 100.00		PSA1_HUMAN (16-261): 4.62e-76: 233: 17.44
+	Hs
		97064 E9PMD8_HUMAN (1-301): 1.06e-81: 250: 100.00		PSB6_HUMAN (41-229): 5.14e-76: 232: 31.58
+	Hs
		97065 E9PMD8_HUMAN (1-301): 1.06e-81: 250: 100.00		PSB5_HUMAN (42-243): 1.59e-74: 230: 26.11
+	Hs
		700565 PRS7_HUMAN (14-300): 4.79e-70: 225: 31.36		PSA5_HUMAN (13-241): 1.34e-82: 249: 18.52
+	Hs
		610227 PRS6A_HUMAN (20-301): 1.67e-75: 239: 95.47		PSA1_HUMAN (16-261): 4.62e-76: 233: 17.44
+	Hs
		610236 PRS6A_HUMAN (20-301): 1.67e-75: 239: 95.47		PSB6_HUMAN (41-229): 5.14e-76: 232: 31.58
+	Hs
		610237 PRS6A_HUMAN (20-301): 1.67e-75: 239: 95.47		PSB5_HUMAN (42-243): 1.59e-74: 230: 26.11
+	Hs
		680794 PRS7_HUMAN (14-300): 4.79e-70: 225: 31.36		PSA1_HUMAN (16-261): 4.62e-76: 233: 17.44
+	Hs
		700991 PRS7_HUMAN (14-300): 4.79e-70: 225: 31.36		PSB6_HUMAN (41-229): 5.14e-76: 232: 31.58
+	Hs
		701105 PRS7_HUMAN (14-300): 4.79e-70: 225: 31.36		PSB5_HUMAN (42-243): 1.59e-74: 230: 26.11
+	Hs
		610233 PRS6A_HUMAN (20-301): 1.67e-75: 239: 95.47		PSB9_HUMAN (42-227): 9.75e-21: 89.7: 29.41
+	Hs
		700498 PRS7_HUMAN (14-300): 4.79e-70: 225: 31.36		PSB9_HUMAN (42-227): 9.75e-21: 89.7: 29.41