HitPredict

Interactor 1: E9PMD8 (E9PMD8)
Proteasome 26S subunit, ATPase 3
Gene: PSMC3

Interactor 2: PSB6 (P28072)
Proteasome subunit beta type-6 (EC 3.4.25.1) (Macropain delta chain) (Multicatalytic endopeptidase complex delta chain) (Proteasome delta chain) (Proteasome subunit Y) (Proteasome subunit beta-1) (beta-1)
Gene: PSMB6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.80	0.514

Property	Details
Experiments	35271311
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	AAA~Proteasome
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 301 Hs			1 239
+	Dm
		874969 PRS4_DROME (51-301): 1.41e-87: 270: 40.00		Q7K148_DROME (31-218): 1.89e-87: 262: 30.69
+	Dm
		47754 PRS4_DROME (51-301): 1.41e-87: 270: 40.00		A0AQH0_DROME (25-237): 5.13e-87: 259: 57.28
+	Dm
		875036 PRS4_DROME (51-301): 1.41e-87: 270: 40.00		Q9VUJ1_DROME (37-219): 2.86e-84: 253: 28.96
+	Dm
		874988 PRS4_DROME (51-301): 1.41e-87: 270: 40.00		PSA5_DROME (3-232): 2.97e-83: 250: 17.62
+	Hs
		97063 E9PMD8_HUMAN (1-301): 1.06e-81: 250: 100.00		PSA5_HUMAN (3-230): 1.87e-84: 253: 18.75
+	Hs
		97083 E9PMD8_HUMAN (1-301): 1.06e-81: 250: 100.00		PSB7_HUMAN (28-229): 5.68e-84: 252: 30.69
+	Hs
		97062 E9PMD8_HUMAN (1-301): 1.06e-81: 250: 100.00		PSA4_HUMAN (6-232): 1.11e-82: 249: 15.19
+	Hs
		610234 PRS6A_HUMAN (20-301): 1.67e-75: 239: 95.47		PSA5_HUMAN (3-230): 1.87e-84: 253: 18.75
+	Hs
		610445 PRS6A_HUMAN (20-301): 1.67e-75: 239: 95.47		PSB7_HUMAN (28-229): 5.68e-84: 252: 30.69
+	Hs
		610230 PRS6A_HUMAN (20-301): 1.67e-75: 239: 95.47		PSA4_HUMAN (6-232): 1.11e-82: 249: 15.19
+	Hs
		97073 E9PMD8_HUMAN (1-301): 1.06e-81: 250: 100.00		PSA6_HUMAN (7-234): 1.38e-78: 238: 15.55
+	Hs
		610233 PRS6A_HUMAN (20-301): 1.67e-75: 239: 95.47		PSB9_HUMAN (30-231): 1.72e-81: 244: 62.38
+	Hs
		165253 PRS6A_HUMAN (20-301): 1.67e-75: 239: 95.47		PSA7_HUMAN (8-231): 3.23e-80: 242: 18.03
+	Hs
		610236 PRS6A_HUMAN (20-301): 1.67e-75: 239: 95.47		PSB6_HUMAN (1-239): 1.05e-79: 240: 100.00
+	Hs
		97065 E9PMD8_HUMAN (1-301): 1.06e-81: 250: 100.00		PSB5_HUMAN (13-235): 1.16e-74: 228: 30.36
+	Hs
		610283 PRS6A_HUMAN (20-301): 1.67e-75: 239: 95.47		PSA6_HUMAN (7-234): 1.38e-78: 238: 15.55
+	Hs
		681583 PRS7_HUMAN (14-300): 4.79e-70: 225: 31.36		PSA4_HUMAN (6-232): 1.11e-82: 249: 15.19
+	Hs
		700498 PRS7_HUMAN (14-300): 4.79e-70: 225: 31.36		PSB9_HUMAN (30-231): 1.72e-81: 244: 62.38
+	Hs
		165277 PRS7_HUMAN (14-300): 4.79e-70: 225: 31.36		PSA7_HUMAN (8-231): 3.23e-80: 242: 18.03
+	Hs
		610237 PRS6A_HUMAN (20-301): 1.67e-75: 239: 95.47		PSB5_HUMAN (13-235): 1.16e-74: 228: 30.36