HitPredict

Interactor 1: ARF6 (P62330)
ADP-ribosylation factor 6 (EC 3.6.5.2)
Gene: ARF6

Interactor 2: COPG1 (Q9Y678)
Coatomer subunit gamma-1 (Gamma-1-coat protein) (Gamma-1-COP)
Gene: COPG1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35844135
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Adaptin_N~Arf
Common GO terms	GO:0005794 - Golgi apparatus GO:0005829 - cytosol GO:0006886 - intracellular protein transport
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 175 Hs			1 874
+	Hs
		612339 ARF4_HUMAN (1-173): 1.28e-70: 212: 64.74		COPG1_HUMAN (1-874): 0: 860: 100.00
+	Hs
		1014988 ARF1_HUMAN (2-175): 2.57e-69: 209: 68.39		COPG1_HUMAN (1-874): 0: 860: 100.00
+	Hs
		1015164 ARF5_HUMAN (2-173): 5.22e-69: 208: 65.12		COPG1_HUMAN (1-874): 0: 860: 100.00
+	Hs
		612325 ARF4_HUMAN (1-173): 1.28e-70: 212: 64.74		COPG2_HUMAN (1-874): 0: 838: 80.55
+	Hs
		1015147 ARF5_HUMAN (2-173): 5.22e-69: 208: 65.12		COPG2_HUMAN (1-874): 0: 838: 80.55
+	Hs
		975290 ARF6_HUMAN (1-175): 2.77e-65: 199: 100.00		COPG2_HUMAN (1-874): 0: 838: 80.55
+	Hs
		958827 ARF3_HUMAN (2-175): 8.25e-65: 198: 69.54		COPG2_HUMAN (1-874): 0: 838: 80.55
+	Dm
		829648 ARF4_DROME (1-173): 2.93e-69: 209: 65.32		COPG_DROME (11-874): 0: 719: 60.28
+	Dm
		958868 ARF1_DROME (2-175): 1.28e-64: 197: 70.12		COPG_DROME (11-874): 0: 719: 60.28
+	Hs
		1014883 ARF1_HUMAN (2-175): 2.57e-69: 209: 68.39		AP1B1_HUMAN (14-872): 0: 651: 13.46
+	Zm
		30141 B4FB55_MAIZE (10-174): 2.69e-66: 203: 18.82		A0A1D6K3D9_MAIZE (63-873): 0: 652: 14.29
+	Hs
		975006 ARF6_HUMAN (1-175): 2.77e-65: 199: 100.00		AP1B1_HUMAN (14-872): 0: 651: 13.46
+	Dm
		829635 ARF4_DROME (1-173): 2.93e-69: 209: 65.32		Q24253_DROME (14-872): 0: 630: 13.50
+	Dm
		958851 ARF1_DROME (2-175): 1.28e-64: 197: 70.12		Q24253_DROME (14-872): 0: 630: 13.50
+	Hs
		974970 ARF6_HUMAN (1-175): 2.77e-65: 199: 100.00		AP2B1_HUMAN (14-871): 0: 592: 12.40
+	Hs
		344663 ARF6_HUMAN (1-175): 2.77e-65: 199: 100.00		AP2A1_HUMAN (24-874): 0: 582: 14.63
+	Hs
		225799 ARF1_HUMAN (2-175): 2.57e-69: 209: 68.39		AP1G1_HUMAN (17-741): 1.36e-170: 517: 15.52
+	Sc
		536090 ARF1_YEAST (2-175): 9.86e-69: 208: 66.09		COPG_YEAST (7-873): 7.82e-169: 516: 32.91
+	Hs
		225795 ARF6_HUMAN (1-175): 2.77e-65: 199: 100.00		AP1G1_HUMAN (17-741): 1.36e-170: 517: 15.52