HitPredict

Interactor 1: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Interactor 2: PTN14 (Q15678)
Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez)
Gene: PTPN14

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	34079125, 31871319
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	FERM_M~Ras
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 196 Hs			1 1187
+	Hs
		988390 RAC1_HUMAN (1-196): 1.47e-79: 236: 55.10		PTN14_HUMAN (1-1187): 0: 995: 100.00
+	Hs
		988705 RAC1_HUMAN (1-196): 1.47e-79: 236: 55.10		E41L1_HUMAN (5-713): 1.41e-142: 455: 17.61
+	Hs
		988842 RAC1_HUMAN (1-196): 1.47e-79: 236: 55.10		E41L3_HUMAN (13-857): 6.26e-133: 435: 17.18
+	Hs
		988321 RAC1_HUMAN (1-196): 1.47e-79: 236: 55.10		PTPRJ_HUMAN (355-1185): 1.01e-127: 426: 15.93
+	Hs
		961995 RHOA_HUMAN (1-196): 4.38e-78: 233: 83.67		PTPRJ_HUMAN (355-1185): 1.01e-127: 426: 15.93
+	Hs
		988700 RAC1_HUMAN (1-196): 1.47e-79: 236: 55.10		E41LB_HUMAN (18-783): 1.31e-129: 420: 16.59
+	Hs
		988333 RAC1_HUMAN (1-196): 1.47e-79: 236: 55.10		PTPRS_HUMAN (555-1181): 8.83e-122: 417: 20.79
+	Hs
		522641 RAC1_HUMAN (1-196): 1.47e-79: 236: 55.10		PTPRF_HUMAN (756-1179): 3.8e-116: 400: 22.61
+	Hs
		522635 RHOA_HUMAN (1-196): 4.38e-78: 233: 83.67		PTPRF_HUMAN (756-1179): 3.8e-116: 400: 22.61
+	Hs
		582741 RAC1_HUMAN (1-196): 1.47e-79: 236: 55.10		EZRI_HUMAN (18-364): 1.2e-120: 387: 20.96
+	Hs
		767417 RAC1_HUMAN (1-196): 1.47e-79: 236: 55.10		RADI_HUMAN (18-364): 8.74e-121: 387: 20.68
+	Hs
		582733 RHOA_HUMAN (1-196): 4.38e-78: 233: 83.67		EZRI_HUMAN (18-364): 1.2e-120: 387: 20.96
+	Hs
		988729 RAC1_HUMAN (1-196): 1.47e-79: 236: 55.10		E41L5_HUMAN (17-319): 4.15e-117: 382: 27.33
+	Hs
		611077 RAC1_HUMAN (1-196): 1.47e-79: 236: 55.10		PTN1_HUMAN (891-1179): 3.3e-118: 375: 31.85
+	Hs
		611069 RHOA_HUMAN (1-196): 4.38e-78: 233: 83.67		PTN1_HUMAN (891-1179): 3.3e-118: 375: 31.85
+	Hs
		988322 RAC1_HUMAN (1-196): 1.47e-79: 236: 55.10		PTN13_HUMAN (1-796): 1.11e-83: 303: 17.54
+	Hs
		705696 RAC1_HUMAN (1-196): 1.47e-79: 236: 55.10		PTPRM_HUMAN (779-1183): 7.71e-70: 259: 18.47
+	Hs
		659013 RAC1_HUMAN (1-196): 1.47e-79: 236: 55.10		PTPRG_HUMAN (289-1185): 3.45e-61: 232: 12.54
+	Hs
		659007 RHOA_HUMAN (1-196): 4.38e-78: 233: 83.67		PTPRG_HUMAN (289-1185): 3.45e-61: 232: 12.54
+	Hs
		607565 RHOA_HUMAN (1-196): 4.38e-78: 233: 83.67		PTN2_HUMAN (928-1179): 1.43e-38: 151: 35.04