HitPredict

Interactor 1: MTG8 (Q06455)
Protein CBFA2T1 (Cyclin-D-related protein) (Eight twenty one protein) (Protein ETO) (Protein MTG8) (Zinc finger MYND domain-containing protein 2)
Gene: RUNX1T1

Interactor 2: HTF4 (Q99081)
Transcription factor 12 (TCF-12) (Class B basic helix-loop-helix protein 20) (bHLHb20) (DNA-binding protein HTF4) (E-box-binding protein) (Transcription factor HTF-4)
Gene: TCF12

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.699

Property	Details
Experiments	19289505, 15333839, 16803958, 31515488
Identification Methods	pull down, affinity chromatography technology, nuclear magnetic resonance, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0140297 - DNA-binding transcription factor binding
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 604 Hs			1 682
+	Hs
		551126 MTG8_HUMAN (1-604): 0: 935: 100.00		ITF2_HUMAN (2-682): 0: 777: 62.01
+	Hs
		254000 MTG16_HUMAN (30-604): 0: 772: 69.18		HTF4_HUMAN (1-682): 0: 921: 100.00
+	Hs
		551510 MTG8_HUMAN (1-604): 0: 935: 100.00		TFE2_HUMAN (2-682): 0: 753: 48.93
+	Mm
		222898 MTG16_MOUSE (31-604): 0: 779: 69.98		HTF4_MOUSE (1-682): 0: 907: 92.21
+	Mm
		222897 MTG16_MOUSE (31-604): 0: 779: 69.98		ITF2_MOUSE (2-682): 0: 804: 62.82
+	Hs
		203437 MTG8R_HUMAN (32-591): 0: 778: 64.77		ITF2_HUMAN (2-682): 0: 777: 62.01
+	Hs
		253964 MTG16_HUMAN (30-604): 0: 772: 69.18		ITF2_HUMAN (2-682): 0: 777: 62.01
+	Hs
		253965 MTG16_HUMAN (30-604): 0: 772: 69.18		TFE2_HUMAN (2-682): 0: 753: 48.93
+	Mm
		222892 MTG16_MOUSE (31-604): 0: 779: 69.98		TFE2_MOUSE (1-682): 0: 732: 49.43