HitPredict

Interactor 1: RL40 (P62987)
Ubiquitin-ribosomal protein eL40 fusion protein (CEP52) (Ubiquitin A-52 residue ribosomal protein fusion product 1) [Cleaved into: Ubiquitin; Large ribosomal subunit protein eL40 (60S ribosomal protein L40) (rpL40)]
Gene: UBA52

Interactor 2: HECD1 (Q9ULT8)
E3 ubiquitin-protein ligase HECTD1 (EC 2.3.2.26) (E3 ligase for inhibin receptor) (EULIR) (HECT domain-containing protein 1)
Gene: HECTD1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	33711283
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	HECT~ubiquitin
Common GO terms	GO:0016567 - protein ubiquitination
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 128 Hs			1 2610
+	Sc
		509886 RL40A_YEAST (1-128): 1.82e-52: 163: 89.84		UFD4_YEAST (2031-2610): 1.68e-129: 449: 28.16
+	Hs
		987478 RL40_HUMAN (1-128): 1.49e-55: 171: 100.00		SMUF2_HUMAN (2235-2607): 8.34e-117: 392: 20.62
+	Hs
		325779 RS27A_HUMAN (1-77): 4.85e-38: 127: 98.70		UBR5_HUMAN (1985-2609): 3.54e-117: 420: 16.94
+	Dm
		94226 RL40_DROME (1-128): 3.9e-55: 170: 97.66		D5SHR3_DROME (2200-2609): 5.16e-115: 375: 19.21
+	Dm
		1489825 Q9W418_DROME (1-77): 1.45e-41: 145: 98.70		Q9W325_DROME (2190-2609): 1.32e-116: 379: 19.23
+	Hs
		507318 UBB_HUMAN (1-76): 5.79e-33: 117: 100.00		ITCH_HUMAN (2234-2608): 3.29e-116: 395: 21.88
+	Hs
		507377 UBB_HUMAN (1-76): 5.79e-33: 117: 100.00		SMUF2_HUMAN (2235-2607): 8.34e-117: 392: 20.62
+	Hs
		131925 RS27A_HUMAN (1-77): 4.85e-38: 127: 98.70		WWP2_HUMAN (2265-2608): 8.98e-108: 369: 24.86
+	Hs
		131689 UBB_HUMAN (1-76): 5.79e-33: 117: 100.00		WWP2_HUMAN (2265-2608): 8.98e-108: 369: 24.86
+	Hs
		987205 RS27A_HUMAN (1-77): 4.85e-38: 127: 98.70		WWP1_HUMAN (2328-2608): 5.34e-91: 321: 29.27
+	Hs
		1050447 Q5U5U6_HUMAN (1-76): 5.79e-33: 117: 100.00		UBE3A_HUMAN (2406-2607): 5.19e-25: 116: 34.95
+	Hs
		507169 UBB_HUMAN (1-76): 5.79e-33: 117: 100.00		UBE3A_HUMAN (2406-2607): 5.19e-25: 116: 34.95
+	Mm
		987293 RS27A_MOUSE (1-77): 5.41e-38: 127: 98.70		HUWE1_MOUSE (2405-2609): 1.01e-18: 96.7: 33.33
+	At
		1167704 UBQ3_ARATH (1-77): 7.33e-35: 123: 94.81		UPL2_ARATH (2424-2604): 7.87e-20: 100: 34.60
+	At
		1167700 UBQ3_ARATH (1-77): 7.33e-35: 123: 94.81		UPL1_ARATH (2424-2604): 1.57e-19: 99.4: 34.60