HitPredict

Interactor 1: RL40A (P0CH08)
Ubiquitin-ribosomal protein eL40A fusion protein [Cleaved into: Ubiquitin; Large ribosomal subunit protein eL40A (60S ribosomal protein L40-A) (CEP52)]
Gene: RPL40A

Interactor 2: UFD4 (P33202)
Ubiquitin fusion degradation protein 4 (UB fusion protein 4) (EC 2.3.2.-) (HECT-type E3 ubiquitin transferase UFD4) (EC 2.3.2.26)
Gene: UFD4

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	16554755
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	HECT~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 128 Sc			1 1483
+	Sc
		509468 UBI4P_YEAST (1-76): 6.49e-42: 143: 100.00		UFD4_YEAST (1-1483): 0: 1249: 100.00
+	Hs
		131925 RS27A_HUMAN (1-88): 1.84e-37: 126: 84.09		WWP2_HUMAN (610-1480): 0: 722: 16.39
+	Hs
		987205 RS27A_HUMAN (1-88): 1.84e-37: 126: 84.09		WWP1_HUMAN (640-1480): 0: 660: 16.18
+	Sc
		509922 RL40A_YEAST (1-128): 8.59e-54: 166: 100.00		TOM1_YEAST (595-1483): 1.37e-167: 562: 16.87
+	Sp
		153855 RL402_SCHPO (1-128): 4.54e-53: 164: 96.88		PUB3_SCHPO (842-1480): 3.51e-180: 558: 17.44
+	Hs
		987478 RL40_HUMAN (1-128): 4e-55: 170: 89.84		SMUF2_HUMAN (905-1479): 2.07e-176: 547: 17.30
+	Sc
		509696 UBI4P_YEAST (1-76): 6.49e-42: 143: 100.00		TOM1_YEAST (595-1483): 1.37e-167: 562: 16.87
+	Sc
		436502 RS31_YEAST (1-76): 9.58e-43: 139: 100.00		TOM1_YEAST (595-1483): 1.37e-167: 562: 16.87
+	Sc
		509564 UBI4P_YEAST (1-76): 6.49e-42: 143: 100.00		RSP5_YEAST (774-1480): 1.02e-176: 550: 15.57
+	Sc
		436424 RS31_YEAST (1-76): 9.58e-43: 139: 100.00		RSP5_YEAST (774-1480): 1.02e-176: 550: 15.57
+	At
		1167704 UBQ3_ARATH (1-77): 4.94e-34: 121: 96.10		UPL2_ARATH (768-1483): 7.2e-158: 534: 18.80
+	Hs
		987359 RL40_HUMAN (1-128): 4e-55: 170: 89.84		HERC3_HUMAN (826-1481): 1.65e-149: 485: 19.36
+	At
		102326 UBQ3_ARATH (1-77): 4.94e-34: 121: 96.10		IMPA2_ARATH (83-591): 2.31e-173: 531: 13.44
+	At
		306055 UBQ3_ARATH (1-77): 4.94e-34: 121: 96.10		IMPA4_ARATH (77-593): 6.6e-155: 482: 15.12
+	Dm
		94226 RL40_DROME (1-128): 2.39e-55: 170: 91.41		D5SHR3_DROME (1031-1480): 1.05e-137: 432: 21.29
+	At
		1167700 UBQ3_ARATH (1-77): 4.94e-34: 121: 96.10		UPL1_ARATH (1025-1483): 9.01e-112: 394: 24.68
+	Hs
		987498 RL40_HUMAN (1-128): 4e-55: 170: 89.84		HECD1_HUMAN (1277-1475): 3.63e-27: 123: 35.44
+	Hs
		987397 RL40_HUMAN (1-128): 4e-55: 170: 89.84		HUWE1_HUMAN (1191-1483): 1.44e-20: 101: 31.51
+	Sp
		151804 UBI4P_SCHPO (1-77): 3.57e-42: 144: 98.70		PTR1_SCHPO (1195-1480): 4.05e-24: 113: 29.11
+	Mm
		987293 RS27A_MOUSE (1-88): 2.06e-37: 125: 84.09		HUWE1_MOUSE (1191-1483): 1.77e-20: 101: 31.51