HitPredict

Interactor 1: GRB2 (P62993)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2

Interactor 2: SMRC2 (Q8TAQ2)
SWI/SNF complex subunit SMARCC2 (BRG1-associated factor 170) (BAF170) (SWI/SNF complex 170 kDa subunit) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2)
Gene: SMARCC2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17474147
Identification Methods	peptide array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 217 Hs			1 1214
+	Hs
		987819 GRB2_HUMAN (1-217): 1.28e-70: 216: 100.00		SMRC1_HUMAN (4-1082): 0: 957: 60.83
+	Hs
		1154136 ITSN1_HUMAN (122-216): 3.21e-11: 64.2: 23.53		SMRC2_HUMAN (1-1203): 0: 991: 100.00
+	Hs
		169499 GRB2_HUMAN (1-217): 1.28e-70: 216: 100.00		HGS_HUMAN (668-1181): 1.12e-46: 182: 19.20
+	Hs
		987935 GRB2_HUMAN (1-217): 1.28e-70: 216: 100.00		PTN23_HUMAN (768-1213): 4.38e-30: 132: 19.59
+	Hs
		215914 GRB2_HUMAN (1-217): 1.28e-70: 216: 100.00		SYNJ1_HUMAN (645-1129): 2.74e-11: 70.5: 9.36
+	Hs
		246648 SH319_HUMAN (8-215): 6.01e-18: 83.5: 17.14		KDM1A_HUMAN (253-543): 2.56e-43: 172: 15.00
+	Hs
		246995 ITSN2_HUMAN (108-216): 6.53e-13: 69.2: 18.92		KDM1A_HUMAN (253-543): 2.56e-43: 172: 15.00
+	Hs
		246396 FYN_HUMAN (161-215): 9.09e-13: 68.5: 31.58		KDM1A_HUMAN (253-543): 2.56e-43: 172: 15.00
+	Hs
		834243 CSK_HUMAN (2-139): 3.94e-24: 100: 36.24		NCOR2_HUMAN (588-1208): 2.07e-32: 139: 14.22
+	Hs
		1205170 SH319_HUMAN (8-215): 6.01e-18: 83.5: 17.14		PTN23_HUMAN (768-1213): 4.38e-30: 132: 19.59
+	Hs
		215893 LCK_HUMAN (3-202): 7.98e-34: 128: 28.44		SYNJ1_HUMAN (645-1129): 2.74e-11: 70.5: 9.36
+	Hs
		1154169 ITSN1_HUMAN (122-216): 3.21e-11: 64.2: 23.53		PTN23_HUMAN (768-1213): 4.38e-30: 132: 19.59
+	Hs
		292868 GRAP2_HUMAN (3-55): 1.97e-10: 61.3: 39.62		PTN23_HUMAN (768-1213): 4.38e-30: 132: 19.59
+	Hs
		557470 SRC_HUMAN (161-215): 3.49e-10: 60.8: 31.58		PTN23_HUMAN (768-1213): 4.38e-30: 132: 19.59
+	Hs
		319045 LYN_HUMAN (129-215): 1.97e-09: 58.5: 22.47		K0754_HUMAN (632-1211): 2.17e-26: 120: 12.33
+	Hs
		215903 NCK1_HUMAN (5-145): 9.5e-23: 96.3: 33.14		SYNJ1_HUMAN (645-1129): 2.74e-11: 70.5: 9.36
+	Hs
		215927 SH319_HUMAN (8-215): 6.01e-18: 83.5: 17.14		SYNJ1_HUMAN (645-1129): 2.74e-11: 70.5: 9.36
+	Hs
		440773 FYN_HUMAN (161-215): 9.09e-13: 68.5: 31.58		MAGL2_HUMAN (959-1203): 5.13e-12: 72.6: 23.29
+	Hs
		215925 ITSN1_HUMAN (122-216): 3.21e-11: 64.2: 23.53		SYNJ1_HUMAN (645-1129): 2.74e-11: 70.5: 9.36
+	Mm
		74245 SRC_MOUSE (161-215): 3.32e-10: 60.8: 31.58		EP300_MOUSE (661-1209): 2.81e-10: 67.4: 12.21