Interactor 1: RAC1 (P63001)
Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (p21-Rac1)
Gene: RAC1
Interactor 2: DOCK1 (Q8BUR4)
Dedicator of cytokinesis protein 1 (180 kDa protein downstream of CRK) (DOCK180)
Gene: DOCK1
Species: Mus musculus
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 21289086 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | DHR-2_Lobe_B~Ras, DHR-2_Lobe_C~Ras, DOCK_N~Ras |
| Common GO terms | GO:0005737 - cytoplasm GO:0007264 - small GTPase-mediated signal transduction GO:0016020 - membrane GO:0016477 - cell migration GO:1900026 - positive regulation of substrate adhesion-dependent cell spreading |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
