HitPredict

Interactor 1: FMR1 (Q06787)
Fragile X messenger ribonucleoprotein 1 (Fragile X messenger ribonucleoprotein) (FMRP) (Protein FMR-1)
Gene: FMR1

Interactor 2: MEP50 (Q9BQA1)
Methylosome protein WDR77 (Androgen receptor cofactor p44) (Methylosome protein 50) (MEP-50) (WD repeat-containing protein 77) (p44/Mep50)
Gene: WDR77

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	28977470
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 632 Hs			1 342
+	Hs
		989045 FMR1_HUMAN (1-632): 0: 1106: 100.00		FBXW7_HUMAN (3-236): 5.23e-43: 159: 14.29
+	Hs
		903160 FMR1_HUMAN (1-632): 0: 1106: 100.00		WDR5_HUMAN (247-341): 5.14e-19: 88.2: 19.79
+	Mm
		729599 FMR1_MOUSE (1-632): 0: 1063: 93.99		TBL1X_MOUSE (162-342): 7.38e-28: 115: 15.46
+	Mm
		729543 FMR1_MOUSE (1-632): 0: 1063: 93.99		TBL1R_MOUSE (154-342): 2.35e-27: 113: 14.85
+	Hs
		843873 FXR1_HUMAN (1-334): 0: 604: 73.95		MEP50_HUMAN (1-342): 6.74e-81: 251: 100.00
+	Mm
		1207102 Q8BPK8_MOUSE (1-357): 0: 688: 97.76		TBL1X_MOUSE (162-342): 7.38e-28: 115: 15.46
+	Mm
		1206587 Q8BPK8_MOUSE (1-357): 0: 688: 97.76		TBL1R_MOUSE (154-342): 2.35e-27: 113: 14.85
+	Hs
		843829 FXR1_HUMAN (1-334): 0: 604: 73.95		FBXW7_HUMAN (3-236): 5.23e-43: 159: 14.29
+	Hs
		843596 FXR1_HUMAN (1-334): 0: 604: 73.95		WDR5_HUMAN (247-341): 5.14e-19: 88.2: 19.79
+	Hs
		844215 FXR2_HUMAN (268-525): 3.17e-50: 186: 30.56		MEP50_HUMAN (1-342): 6.74e-81: 251: 100.00
+	Hs
		843998 FXR2_HUMAN (268-525): 3.17e-50: 186: 30.56		WDR5_HUMAN (247-341): 5.14e-19: 88.2: 19.79