HitPredict

Interactor 1: TLE5 (Q08117)
TLE family member 5 (Amino-terminal enhancer of split) (Amino enhancer of split) (Gp130-associated protein GAM) (Grg-5) (Groucho-related protein 5) (Protein ESP1) (Protein GRG) (TLE family member 5, transcriptional modulator)
Gene: TLE5

Interactor 2: KLF1 (Q13351)
Krueppel-like factor 1 (Erythroid krueppel-like transcription factor) (EKLF)
Gene: KLF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.60	0.606

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid array, validated two hybrid, two hybrid prey pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 197 Hs			1 362
+	Hs
		993504 TLE5_HUMAN (1-197): 3.1e-101: 292: 100.00		ZN383_HUMAN (67-334): 1.68e-98: 301: 19.49
+	Hs
		993497 TLE5_HUMAN (1-197): 3.1e-101: 292: 100.00		ZNF34_HUMAN (67-306): 1.09e-78: 253: 11.07
+	Hs
		204165 TLE1_HUMAN (2-197): 2.47e-111: 336: 64.50		KLF4_HUMAN (258-362): 5.56e-44: 160: 79.05
+	Hs
		980959 TLE4_HUMAN (2-191): 3.57e-112: 338: 68.59		KLF12_HUMAN (255-362): 4.34e-40: 147: 65.74
+	Hs
		980601 TLE1_HUMAN (2-197): 2.47e-111: 336: 64.50		KLF5_HUMAN (263-361): 1.07e-38: 145: 73.00
+	Hs
		884133 TLE1_HUMAN (2-197): 2.47e-111: 336: 64.50		KLF3_HUMAN (273-362): 2.16e-34: 131: 71.11
+	Hs
		980748 TLE3_HUMAN (2-197): 3.95e-105: 320: 61.50		KLF5_HUMAN (263-361): 1.07e-38: 145: 73.00
+	Hs
		204169 TLE5_HUMAN (1-197): 3.1e-101: 292: 100.00		KLF4_HUMAN (258-362): 5.56e-44: 160: 79.05
+	Hs
		884134 TLE3_HUMAN (2-197): 3.95e-105: 320: 61.50		KLF3_HUMAN (273-362): 2.16e-34: 131: 71.11
+	Hs
		993418 TLE5_HUMAN (1-197): 3.1e-101: 292: 100.00		KLF5_HUMAN (263-361): 1.07e-38: 145: 73.00
+	Hs
		316865 TLE5_HUMAN (1-197): 3.1e-101: 292: 100.00		KLF8_HUMAN (248-361): 3.01e-38: 141: 60.53
+	Hs
		884139 TLE5_HUMAN (1-197): 3.1e-101: 292: 100.00		KLF3_HUMAN (273-362): 2.16e-34: 131: 71.11
+	Ce
		137695 UNC37_CAEEL (18-160): 8.43e-43: 153: 28.47		KLF1_CAEEL (279-362): 9.82e-44: 159: 80.95
+	Ce
		137683 UNC37_CAEEL (18-160): 8.43e-43: 153: 28.47		SPTF2_CAEEL (261-358): 5.83e-31: 117: 52.04