Protein: DCUP
Uroporphyrinogen decarboxylase (UPD) (URO-D) (EC 4.1.1.37)

Gene: DCUP, UROD
Organism: Homo sapiens
Interactions: 37
UniProt ID: P06132

Gene Ontology (top 5):
GO:0004853 - uroporphyrinogen decarboxylase activity
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0006778 - porphyrin-containing compound metabolic process
GO:0006782 - protoporphyrinogen IX biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

438955

PPID
Peptidyl-prolyl cis-trans isomerase D

2

0

High-throughput

0.585

High

362592

EGFR
Epidermal growth factor receptor

2

0

Small-scale

0.582

High

438952

KPB2
Phosphorylase b kinase regulatory subunit alpha, liver isoform

2

0

High-throughput

0.580

High

438943

DCUP
Uroporphyrinogen decarboxylase

1

2

Small-scale

0.575

High

438954

RUNX1
Runt-related transcription factor 1

1

0

High-throughput

0.518

High

438945

VIME
Vimentin

1

0

High-throughput

0.486

High

438956

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

0

High-throughput

0.486

High

438970

FAF1
FAS-associated factor 1

1

0

High-throughput

0.486

High

438972

FBX7
F-box only protein 7

1

0

High-throughput

0.480

High

91706

C9JJ79
Paired immunoglobin like type 2 receptor alpha

1

1

High-throughput

0.470

High

347464

BAG3
BAG family molecular chaperone regulator 3

1

0

High-throughput

0.458

High

438948

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

438950

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

438951

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

438953

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.458

High

438959

WIPI3
WD repeat domain phosphoinositide-interacting protein 3

1

0

High-throughput

0.458

High

438967

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

438957

KCAB2
Voltage-gated potassium channel subunit beta-2

1

1

High-throughput

0.445

High

438958

KCAB1
Voltage-gated potassium channel subunit beta-1

1

1

High-throughput

0.445

High

438969

PILRA
Paired immunoglobulin-like type 2 receptor alpha

1

1

High-throughput

0.439

High

438944

ELNE
Neutrophil elastase

1

0

Small-scale

0.438

High

438966

DDX28
Probable ATP-dependent RNA helicase DDX28

1

0

High-throughput

0.426

High

438971

GAB2
GRB2-associated-binding protein 2

1

0

High-throughput

0.426

High

438962

LRAT2
Protein LRATD2

4

0

High-throughput

0.364

High

62884

POTEF
POTE ankyrin domain family member F

3

0

High-throughput

0.342

High

438965

CPNE5
Copine-5

2

0

High-throughput

0.328

High

438963

TSSK3
Testis-specific serine/threonine-protein kinase 3

2

0

High-throughput

0.316

High

438968

HMGX4
HMG domain-containing protein 4

1

0

High-throughput

0.265

Low

438960

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

438964

ACE2
Angiotensin-converting enzyme 2

1

0

High-throughput

0.249

Low

48224

TM129
E3 ubiquitin-protein ligase TM129

1

0

High-throughput

0.232

Low

369809

CO3
Complement C3

1

0

High-throughput

0.232

Low

438946

VSIG8
V-set and immunoglobulin domain-containing protein 8

1

0

High-throughput

0.232

Low

438947

ITF2
Transcription factor 4

1

0

High-throughput

0.232

Low

438949

ANFB
Natriuretic peptides B

1

0

High-throughput

0.232

Low

438961

LYG2
Lysozyme g-like protein 2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025