Protein: OAS3
2'-5'-oligoadenylate synthase 3 ((2-5')oligo(A) synthase 3) (2-5A synthase 3) (EC 2.7.7.84) (p100 OAS) (p100OAS)

Gene: OAS3
Organism: Homo sapiens
Interactions: 63
UniProt ID: Q9Y6K5

Gene Ontology (top 5):
GO:0001730 - 2'-5'-oligoadenylate synthetase activity
GO:0003725 - double-stranded RNA binding
GO:0005524 - ATP binding
GO:0005615 - extracellular space
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1381081

ZN622
Cytoplasmic 60S subunit biogenesis factor ZNF622

2

0

High-throughput

0.602

High

1419750

GTPB4
GTP-binding protein 4

2

0

High-throughput

0.602

High

1271633

DHX30
ATP-dependent RNA helicase DHX30

1

3

High-throughput

0.586

High

1314288

SPB1
pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3

1

1

High-throughput

0.586

High

941318

IF6
Eukaryotic translation initiation factor 6

1

0

High-throughput

0.561

High

1278168

MAVS
Mitochondrial antiviral-signaling protein

1

0

High-throughput

0.561

High

243450

PRKN
E3 ubiquitin-protein ligase parkin

2

0

High-throughput

0.559

High

187227

PPM1G
Protein phosphatase 1G

1

1

High-throughput

0.536

High

257205

CCD22
Coiled-coil domain-containing protein 22

1

1

High-throughput

0.536

High

595666

H15
Histone H1.5

1

3

High-throughput

0.536

High

838816

MTREX
Exosome RNA helicase MTR4

1

1

High-throughput

0.536

High

1102146

PABP4
Polyadenylate-binding protein 4

1

2

High-throughput

0.536

High

1117728

NOG2
Nucleolar GTP-binding protein 2

1

3

High-throughput

0.536

High

1415589

GNL3
Guanine nucleotide-binding protein-like 3

1

3

High-throughput

0.536

High

1447267

EXOS3
Exosome complex component RRP40

1

1

High-throughput

0.536

High

1450722

GNL3L
Guanine nucleotide-binding protein-like 3-like protein

1

3

High-throughput

0.536

High

1451847

LYAR
Cell growth-regulating nucleolar protein

1

1

High-throughput

0.536

High

1453476

NOP53
Ribosome biogenesis protein NOP53

1

1

High-throughput

0.536

High

1462090

PRP19
Pre-mRNA-processing factor 19

1

1

High-throughput

0.536

High

1491169

NOP16
Nucleolar protein 16

1

1

High-throughput

0.536

High

428258

RLA1
Large ribosomal subunit protein P1

1

0

High-throughput

0.513

High

542302

TOP1
DNA topoisomerase 1

1

0

High-throughput

0.513

High

769814

RFC4
Replication factor C subunit 4

1

0

High-throughput

0.513

High

854406

KI67
Proliferation marker protein Ki-67

1

0

High-throughput

0.513

High

888428

MCM2
DNA replication licensing factor MCM2

1

0

High-throughput

0.513

High

984671

RL39
Large ribosomal subunit protein eL39

1

0

High-throughput

0.513

High

1032281

EXOSX
Exosome complex component 10

1

0

High-throughput

0.513

High

1126594

CAPR1
Caprin-1

1

0

High-throughput

0.513

High

1404558

CDC5L
Cell division cycle 5-like protein

1

0

High-throughput

0.513

High

1446307

NOP10
H/ACA ribonucleoprotein complex subunit 3

1

0

High-throughput

0.513

High

1450849

SDA1
Protein SDA1 homolog

1

0

High-throughput

0.513

High

1462246

G3BP2
Ras GTPase-activating protein-binding protein 2

1

0

High-throughput

0.513

High

1491348

TLN1
Talin-1

1

0

High-throughput

0.513

High

596448

H12
Histone H1.2

1

3

High-throughput

0.489

High

847460

GPDM
Glycerol-3-phosphate dehydrogenase, mitochondrial

1

1

High-throughput

0.489

High

1411831

LLPH
Protein LLP homolog

1

1

High-throughput

0.489

High

158043

CTRO
Citron Rho-interacting kinase

1

1

High-throughput

0.479

High

483668

CN37
2',3'-cyclic-nucleotide 3'-phosphodiesterase

1

1

High-throughput

0.479

High

538193

HSP7C
Heat shock cognate 71 kDa protein

1

1

High-throughput

0.479

High

687549

PTBP1
Polypyrimidine tract-binding protein 1

1

5

High-throughput

0.479

High

714562

PML
Protein PML

1

2

High-throughput

0.479

High

1256317

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.479

High

1367717

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

1437946

SP110
Sp110 nuclear body protein

1

2

High-throughput

0.479

High

1447517

ANLN
Anillin

1

1

High-throughput

0.479

High

227728

SPOP
Speckle-type POZ protein

1

0

High-throughput

0.458

High

373652

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

401786

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

412909

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.458

High

482568

F16P1
Fructose-1,6-bisphosphatase 1

1

0

High-throughput

0.458

High

1114789

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1156923

E2F4
Transcription factor E2F4

1

0

High-throughput

0.458

High

1380303

FBXW7
F-box/WD repeat-containing protein 7

1

0

High-throughput

0.458

High

1458579

HDAC6
Protein deacetylase HDAC6

1

0

High-throughput

0.458

High

1461516

BRPF3
Bromodomain and PHD finger-containing protein 3

1

0

High-throughput

0.458

High

117319

K7ERC4
2',3'-cyclic nucleotide 3' phosphodiesterase

1

1

High-throughput

0.445

High

1199778

KLH22
Kelch-like protein 22

1

0

High-throughput

0.426

High

1401918

NUDC1
NudC domain-containing protein 1

1

0

High-throughput

0.426

High

66826

A6NLN1
Polypyrimidine tract-binding protein 1

1

4

High-throughput

0.407

High

69590

A8K3Q9
Large ribosomal subunit protein eL14

1

1

High-throughput

0.407

High

1089189

IFRD2
Interferon-related developmental regulator 2

1

0

High-throughput

0.306

High

97198

CK098
Uncharacterized protein C11orf98

1

0

High-throughput

0.232

Low

653689

HEMH
Ferrochelatase, mitochondrial

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025