Protein: 5HT3C
5-hydroxytryptamine receptor 3C (5-HT3-C) (5-HT3C) (Serotonin receptor 3C)

Gene: 5HT3C, HTR3C
Organism: Homo sapiens
Interactions: 89
UniProt ID: Q8WXA8

Gene Ontology (top 5):
GO:0005231 - excitatory extracellular ligand-gated monoatomic ion channel activity
GO:0005886 - plasma membrane
GO:0007210 - serotonin receptor signaling pathway
GO:0022848 - acetylcholine-gated monoatomic cation-selective channel activity
GO:0022850 - serotonin-gated monoatomic cation channel activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

526521

GP1BB
Platelet glycoprotein Ib beta chain

3

4

High-throughput

0.667

High

567197

CXA1
Gap junction alpha-1 protein

3

3

High-throughput

0.667

High

1035090

TUSC3
Tumor suppressor candidate 3

3

6

High-throughput

0.667

High

1135417

WLS
Protein wntless homolog

3

3

High-throughput

0.667

High

1219407

LRC8A
Volume-regulated anion channel subunit LRRC8A

3

7

High-throughput

0.667

High

1253847

SPP2B
Signal peptide peptidase-like 2B

3

9

High-throughput

0.667

High

1263263

S47A1
Multidrug and toxin extrusion protein 1

3

2

High-throughput

0.667

High

1263266

LRFN3
Leucine-rich repeat and fibronectin type-III domain-containing protein 3

3

2

High-throughput

0.667

High

802367

5HT3A
5-hydroxytryptamine receptor 3A

1

15

Small-scale

0.665

High

1048506

DAG1
Dystroglycan 1

3

0

High-throughput

0.638

High

546667

B4GT1
Beta-1,4-galactosyltransferase 1

2

3

High-throughput

0.611

High

1053385

FZD2
Frizzled-2

2

4

High-throughput

0.611

High

1193306

T179B
Transmembrane protein 179B

2

1

High-throughput

0.611

High

1218427

IPRI
Inositol 1,4,5-trisphosphate receptor-interacting protein

2

4

High-throughput

0.611

High

1263258

EDA
Ectodysplasin-A

2

4

High-throughput

0.611

High

1263260

ASTRA
Protein Aster-A

2

8

High-throughput

0.611

High

238891

TPST2
Protein-tyrosine sulfotransferase 2

3

5

High-throughput

0.609

High

1110333

UD3A2
UDP-glucuronosyltransferase 3A2

3

4

High-throughput

0.609

High

1134690

DIK1A
Divergent protein kinase domain 1A

3

5

High-throughput

0.609

High

1170474

TMPPE
Transmembrane protein with metallophosphoesterase domain

3

3

High-throughput

0.609

High

1173496

TMTC3
Protein O-mannosyl-transferase TMTC3

3

6

High-throughput

0.609

High

1187505

ERMP1
Endoplasmic reticulum metallopeptidase 1

3

3

High-throughput

0.609

High

1241165

NETO2
Neuropilin and tolloid-like protein 2

3

6

High-throughput

0.609

High

1256698

PIGO
GPI ethanolamine phosphate transferase 3

3

5

High-throughput

0.609

High

1263259

TM186
Transmembrane protein 186

3

1

High-throughput

0.609

High

1263268

SC11C
Signal peptidase complex catalytic subunit SEC11C

3

3

High-throughput

0.609

High

1263273

TM231
Transmembrane protein 231

3

2

High-throughput

0.609

High

1263274

ALG9
Alpha-1,2-mannosyltransferase ALG9

3

8

High-throughput

0.609

High

1263276

S38AA
Solute carrier family 38 member 10

3

2

High-throughput

0.609

High

1263277

CHSTC
Carbohydrate sulfotransferase 12

3

3

High-throughput

0.609

High

1263278

TM39A
Transmembrane protein 39A

3

8

High-throughput

0.609

High

1263286

POMT1
Protein O-mannosyl-transferase 1

3

9

High-throughput

0.609

High

49150

TM223
Transmembrane protein 223

2

3

High-throughput

0.558

High

952916

RHG08
Rho GTPase-activating protein 8

2

2

High-throughput

0.558

High

1137674

MANEL
Glycoprotein endo-alpha-1,2-mannosidase-like protein

2

2

High-throughput

0.558

High

1192842

TMED4
Transmembrane emp24 domain-containing protein 4

2

1

High-throughput

0.558

High

1256001

RHBL4
Rhomboid-related protein 4

2

2

High-throughput

0.558

High

1263261

F241B
Protein FAM241B

2

1

High-throughput

0.558

High

1263267

LMF2
Lipase maturation factor 2

2

8

High-throughput

0.558

High

1263282

POMT2
Protein O-mannosyl-transferase 2

2

9

High-throughput

0.558

High

1263284

MAN1
Inner nuclear membrane protein Man1

2

7

High-throughput

0.558

High

1083536

SGCB
Beta-sarcoglycan

1

4

High-throughput

0.536

High

1239939

SIDT2
SID1 transmembrane family member 2

1

6

High-throughput

0.536

High

1069029

NOMO1
BOS complex subunit NOMO1

1

3

High-throughput

0.489

High

1147558

GL8D1
Glycosyltransferase 8 domain-containing protein 1

1

4

High-throughput

0.489

High

1263281

TM59L
Transmembrane protein 59-like

1

2

High-throughput

0.489

High

260243

ENTP6
Ectonucleoside triphosphate diphosphohydrolase 6

1

4

High-throughput

0.479

High

277727

PRAF3
PRA1 family protein 3

1

1

High-throughput

0.479

High

1203967

LSR
Lipolysis-stimulated lipoprotein receptor

1

5

High-throughput

0.479

High

1239527

AT11C
Phospholipid-transporting ATPase IG

1

2

High-throughput

0.479

High

1240084

TM87A
Transmembrane protein 87A

1

3

High-throughput

0.479

High

1259748

ABHD3
Phospholipase ABHD3

1

1

High-throughput

0.479

High

1263270

SEM4C
Semaphorin-4C

1

2

High-throughput

0.479

High

1263275

PACC1
Proton-activated chloride channel

1

2

High-throughput

0.479

High

1263279

CC50A
Cell cycle control protein 50A

1

1

High-throughput

0.479

High

81932

B7ZMA4
LOC553158 protein

1

2

High-throughput

0.437

High

200049

GPAA1
Glycosylphosphatidylinositol anchor attachment 1 protein

1

1

High-throughput

0.437

High

299697

SUN1
SUN domain-containing protein 1

1

2

High-throughput

0.437

High

946421

EREP3
Protein ENTREP3

1

4

High-throughput

0.437

High

957446

IDD
Integral membrane protein DGCR2/IDD

1

2

High-throughput

0.437

High

1138549

DIK1B
Divergent protein kinase domain 1B

1

5

High-throughput

0.437

High

1175998

PGAP1
GPI inositol-deacylase

1

2

High-throughput

0.437

High

1204801

GOLI
E3 ubiquitin-protein ligase RNF130

1

10

High-throughput

0.437

High

1223548

K2013
Uncharacterized protein KIAA2013

1

2

High-throughput

0.437

High

1242786

DIK2A
Divergent protein kinase domain 2A

1

4

High-throughput

0.437

High

1253233

RDH11
Retinol dehydrogenase 11

1

1

High-throughput

0.437

High

1263262

C1GLC
C1GALT1-specific chaperone 1

1

3

High-throughput

0.437

High

1263265

LMF1
Lipase maturation factor 1

1

8

High-throughput

0.437

High

1263269

FUT8
Alpha-(1,6)-fucosyltransferase

1

4

High-throughput

0.437

High

1263271

LNP
Endoplasmic reticulum junction formation protein lunapark

1

1

High-throughput

0.437

High

1263283

SPG7
Mitochondrial inner membrane m-AAA protease component paraplegin

1

1

High-throughput

0.437

High

1263285

TMX2
Thioredoxin-related transmembrane protein 2

1

2

High-throughput

0.437

High

69702

B1AHC3
PRR5-ARHGAP8 readthrough

1

2

High-throughput

0.407

High

327013

ABHGA
Phosphatidylserine lipase ABHD16A

3

0

High-throughput

0.347

High

1236274

MET25
Probable methyltransferase-like protein 25

3

0

High-throughput

0.347

High

1240546

S38A9
Neutral amino acid transporter 9

3

0

High-throughput

0.347

High

1242815

TM104
Transmembrane protein 104

3

0

High-throughput

0.347

High

1252069

S35B2
Adenosine 3'-phospho 5'-phosphosulfate transporter 1

3

0

High-throughput

0.347

High

1263272

PIGM
GPI mannosyltransferase 1

3

0

High-throughput

0.347

High

1263280

IMPA3
Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase

3

0

High-throughput

0.347

High

123397

GET1
Guided entry of tail-anchored proteins factor 1

2

0

High-throughput

0.318

High

963080

PLIN5
Perilipin-5

1

0

High-throughput

0.279

Low

202935

EMC8
ER membrane protein complex subunit 8

1

0

High-throughput

0.249

Low

643235

MGAT1
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase

1

0

High-throughput

0.249

Low

1077682

NSDHL
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating

1

0

High-throughput

0.249

Low

1124768

AG10A
Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase

1

0

High-throughput

0.249

Low

1127431

NHLC3
NHL repeat-containing protein 3

1

0

High-throughput

0.249

Low

1263257

BRI3B
BRI3-binding protein

1

0

High-throughput

0.249

Low

1263264

MBOA7
Lysophospholipid acyltransferase 7

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024