Protein: HPLN2
Hyaluronan and proteoglycan link protein 2 (Brain link protein 1)

Gene: HPLN2, HAPLN2
Organism: Homo sapiens
Interactions: 49
UniProt ID: Q9GZV7

Gene Ontology (top 5):
GO:0001501 - skeletal system development
GO:0005540 - hyaluronic acid binding
GO:0005615 - extracellular space
GO:0007155 - cell adhesion
GO:0007417 - central nervous system development

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1116584

FHL3
Four and a half LIM domains protein 3

2

2

High-throughput

0.700

High

1198278

FND3B
Fibronectin type III domain-containing protein 3B

2

9

High-throughput

0.700

High

1216155

FHL5
Four and a half LIM domains protein 5

2

2

High-throughput

0.700

High

1361063

ASB13
Ankyrin repeat and SOCS box protein 13

2

2

High-throughput

0.700

High

1403314

PP16B
Protein phosphatase 1 regulatory inhibitor subunit 16B

2

2

High-throughput

0.700

High

1429044

TRIM1
Probable E3 ubiquitin-protein ligase MID2

2

14

High-throughput

0.700

High

938284

SEC13
Protein SEC13 homolog

2

0

High-throughput

0.655

High

1330226

ZN655
Zinc finger protein 655

2

0

High-throughput

0.655

High

300491

KRT34
Keratin, type I cuticular Ha4

2

8

High-throughput

0.606

High

1007540

KRT85
Keratin, type II cuticular Hb5

2

1

High-throughput

0.606

High

1127681

KT33B
Keratin, type I cuticular Ha3-II

2

8

High-throughput

0.606

High

1146154

K1H1
Keratin, type I cuticular Ha1

2

8

High-throughput

0.606

High

1180125

VWC2
Brorin

2

5

High-throughput

0.606

High

1367982

KRT35
Keratin, type I cuticular Ha5

2

8

High-throughput

0.606

High

517109

NT2NC
Notch homolog 2 N-terminal-like protein C

1

5

High-throughput

0.594

High

220803

PPIP1
Proline-serine-threonine phosphatase-interacting protein 1

2

0

High-throughput

0.580

High

1277399

NT2NA
Notch homolog 2 N-terminal-like protein A

1

4

High-throughput

0.555

High

65160

GG6L9
Golgin subfamily A member 6-like protein 9

2

3

High-throughput

0.553

High

300692

KRT37
Keratin, type I cuticular Ha7

2

8

High-throughput

0.553

High

572200

TRI27
Zinc finger protein RFP

2

7

High-throughput

0.553

High

618107

K1C15
Keratin, type I cytoskeletal 15

2

7

High-throughput

0.553

High

783407

TRI23
E3 ubiquitin-protein ligase TRIM23

2

2

High-throughput

0.553

High

950675

KR108
Keratin-associated protein 10-8

2

11

High-throughput

0.553

High

1186704

KRA62
Keratin-associated protein 6-2

2

1

High-throughput

0.553

High

1205980

MTUS2
Microtubule-associated tumor suppressor candidate 2

2

3

High-throughput

0.553

High

1230252

K1C40
Keratin, type I cytoskeletal 40

2

8

High-throughput

0.553

High

1277628

K1C27
Keratin, type I cytoskeletal 27

2

4

High-throughput

0.553

High

1336469

PNMA1
Paraneoplastic antigen Ma1

2

1

High-throughput

0.553

High

1419034

KRA92
Keratin-associated protein 9-2

2

7

High-throughput

0.553

High

1429045

PNMA2
Paraneoplastic antigen Ma2

2

1

High-throughput

0.553

High

1419144

KRA24
Keratin-associated protein 2-4

1

7

High-throughput

0.470

High

628

NBPFJ
NBPF family member NBPF19

1

3

High-throughput

0.439

High

505382

KRA23
Keratin-associated protein 2-3

1

7

High-throughput

0.439

High

106621

APRIO
Alternative prion protein

1

5

High-throughput

0.437

High

217198

MS18B
Protein Mis18-beta

2

0

High-throughput

0.316

High

1086311

TFCP2
Alpha-globin transcription factor CP2

2

0

High-throughput

0.316

High

1186913

KR195
Keratin-associated protein 19-5

2

0

High-throughput

0.316

High

1278739

ZN438
Zinc finger protein 438

2

0

High-throughput

0.316

High

1295773

CC125
Coiled-coil domain-containing protein 125

2

0

High-throughput

0.316

High

1315436

P20D2
Xaa-Arg dipeptidase

2

0

High-throughput

0.316

High

1332037

BANP
Protein BANP

2

0

High-throughput

0.316

High

1384018

EXOS8
Exosome complex component RRP43

2

0

High-throughput

0.316

High

1404662

PFD5
Prefoldin subunit 5

2

0

High-throughput

0.316

High

1407080

MDFI
MyoD family inhibitor

2

0

High-throughput

0.316

High

1429042

ZMY12
Zinc finger MYND domain-containing protein 12

2

0

High-throughput

0.316

High

1429043

CIDEB
Lipid transferase CIDEB

2

0

High-throughput

0.316

High

1186801

KRA63
Keratin-associated protein 6-3

1

0

High-throughput

0.268

Low

243868

GRIN2
G protein-regulated inducer of neurite outgrowth 2

1

0

High-throughput

0.251

Low

1356088

SRB4D
Scavenger receptor cysteine-rich domain-containing group B protein

1

0

High-throughput

0.251

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025