Protein: AP5S1
AP-5 complex subunit sigma-1 (Adaptor-related protein complex 5 sigma subunit) (Sigma5)

Gene: AP5S1
Organism: Homo sapiens
Interactions: 20
UniProt ID: Q9NUS5

Gene Ontology (top 5):
GO:0000724 - double-strand break repair via homologous recombination
GO:0005654 - nucleoplasm
GO:0005764 - lysosome
GO:0005765 - lysosomal membrane
GO:0005770 - late endosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1180661

AP5B1
AP-5 complex subunit beta-1

2

0

Small-scale

0.592

High

1430290

AP5M1
AP-5 complex subunit mu-1

2

0

Small-scale

0.592

High

1437199

CSN7B
COP9 signalosome complex subunit 7b

1

1

High-throughput

0.536

High

1450095

CSN7A
COP9 signalosome complex subunit 7a

1

1

High-throughput

0.536

High

1450097

CSN3
COP9 signalosome complex subunit 3

1

1

High-throughput

0.536

High

212888

AP5Z1
AP-5 complex subunit zeta-1

1

0

High-throughput

0.513

High

1007612

PRAME
Melanoma antigen preferentially expressed in tumors

1

0

High-throughput

0.513

High

1094424

CSN1
COP9 signalosome complex subunit 1

1

0

High-throughput

0.513

High

1228891

ZFY26
Zinc finger FYVE domain-containing protein 26

1

0

High-throughput

0.513

High

1272572

CSN6
COP9 signalosome complex subunit 6

1

0

High-throughput

0.513

High

1395033

SPTCS
Spatacsin

1

0

High-throughput

0.513

High

1411015

ACBD6
Acyl-CoA-binding domain-containing protein 6

1

0

High-throughput

0.513

High

1413205

CSN4
COP9 signalosome complex subunit 4

1

0

High-throughput

0.513

High

1450093

MRGBP
MRG/MORF4L-binding protein

1

0

High-throughput

0.513

High

1450094

MO4L1
Mortality factor 4-like protein 1

1

0

High-throughput

0.513

High

162863

NHRF1
Na(+)/H(+) exchange regulatory cofactor NHE-RF1

1

0

High-throughput

0.279

Low

749406

TNFL8
Tumor necrosis factor ligand superfamily member 8

1

0

High-throughput

0.279

Low

1450096

XPO7
Exportin-7

1

0

High-throughput

0.249

Low

50710

HACL2
2-hydroxyacyl-CoA lyase 2

1

0

High-throughput

0.232

Low

1010976

BAT1
b(0,+)-type amino acid transporter 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025