Protein: MRGBP
MRG/MORF4L-binding protein (MRG-binding protein) (Up-regulated in colon cancer 4) (Urcc4)

Gene: MRGBP
Organism: Homo sapiens
Interactions: 107
UniProt ID: Q9NV56

Gene Ontology (top 5):
GO:0000786 - nucleosome
GO:0005654 - nucleoplasm
GO:0006325 - chromatin organization
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0035267 - NuA4 histone acetyltransferase complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1450239

MO4L1
Mortality factor 4-like protein 1

19

2

Small-scale

0.766

High

1136866

MO4L2
Mortality factor 4-like protein 2

13

2

Small-scale

0.760

High

1371307

KAT5
Histone acetyltransferase KAT5

10

1

Small-scale

0.753

High

1446331

DMAP1
DNA methyltransferase 1-associated protein 1

7

1

Small-scale

0.745

High

1431817

EPC1
Enhancer of polycomb homolog 1

7

1

Small-scale

0.744

High

1450244

RUVB2
RuvB-like 2

6

2

Small-scale

0.732

High

1450245

RUVB1
RuvB-like 1

6

2

Small-scale

0.732

High

1396751

EP400
E1A-binding protein p400

6

3

Small-scale

0.727

High

1155332

VPS72
Vacuolar protein sorting-associated protein 72 homolog

6

1

Small-scale

0.727

High

1429944

BRD8
Bromodomain-containing protein 8

11

0

Small-scale

0.724

High

1450237

ING3
Inhibitor of growth protein 3

5

2

Small-scale

0.714

High

340415

YETS4
YEATS domain-containing protein 4

7

0

Small-scale

0.714

High

1198119

EPC2
Enhancer of polycomb homolog 2

5

1

Small-scale

0.709

High

1244943

FOXR1
Forkhead box protein R1

4

1

High-throughput

0.699

High

502149

H2AZ
Histone H2A.Z

4

1

Small-scale

0.691

High

1053314

MBTD1
MBT domain-containing protein 1

5

0

Small-scale

0.688

High

1437537

EAF6
Chromatin modification-related protein MEAF6

5

0

Small-scale

0.684

High

355308

ACL6A
Actin-like protein 6A

4

4

Small-scale

0.683

High

1450246

TRRAP
Transformation/transcription domain-associated protein

4

0

Small-scale

0.672

High

1245364

FOXR2
Forkhead box protein R2

3

1

High-throughput

0.667

High

1381872

H2B1A
Histone H2B type 1-A

3

2

High-throughput

0.667

High

373278

MYC
Myc proto-oncogene protein

3

2

High-throughput

0.633

High

142626

IMA3
Importin subunit alpha-3

2

2

High-throughput

0.628

High

553769

MYCL
Protein L-Myc

2

2

High-throughput

0.628

High

950419

KR107
Keratin-associated protein 10-7

3

1

High-throughput

0.616

High

981131

H2B1C
Histone H2B type 1-C/E/F/G/I

2

2

High-throughput

0.584

High

1450248

MOFA1
MORF4 family-associated protein 1

2

1

Small-scale

0.584

High

1277426

NT2NA
Notch homolog 2 N-terminal-like protein A

2

1

High-throughput

0.578

High

274388

SIN3B
Paired amphipathic helix protein Sin3b

2

0

Small-scale

0.559

High

1059752

KRA11
Keratin-associated protein 1-1

2

1

High-throughput

0.553

High

1235817

KRA57
Keratin-associated protein 5-7

2

2

High-throughput

0.553

High

1209714

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

1

Small-scale

0.536

High

138775

IMA4
Importin subunit alpha-4

1

2

High-throughput

0.536

High

833784

KDM5C
Lysine-specific demethylase 5C

1

1

High-throughput

0.536

High

1361588

ING5
Inhibitor of growth protein 5

1

2

High-throughput

0.536

High

1413614

AN32E
Acidic leucine-rich nuclear phosphoprotein 32 family member E

1

1

Small-scale

0.536

High

1450241

ING1
Inhibitor of growth protein 1

1

2

Small-scale

0.536

High

761901

HSP74
Heat shock 70 kDa protein 4

2

1

Small-scale

0.533

High

920513

DAPK1
Death-associated protein kinase 1

1

0

High-throughput

0.513

High

301235

RL1D1
Ribosomal L1 domain-containing protein 1

1

0

Small-scale

0.513

High

1371728

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

0

High-throughput

0.513

High

1450093

AP5S1
AP-5 complex subunit sigma-1

1

0

High-throughput

0.513

High

1256386

E400N
Putative EP400-like protein

2

1

High-throughput

0.504

High

1450247

MFHA1
Malignant fibrous histiocytoma-amplified sequence 1

1

1

High-throughput

0.489

High

260518

BRD4
Bromodomain-containing protein 4

1

2

High-throughput

0.479

High

674349

BRD2
Bromodomain-containing protein 2

1

3

High-throughput

0.479

High

711843

KDM5A
Lysine-specific demethylase 5A

1

1

High-throughput

0.479

High

911128

IMA1
Importin subunit alpha-1

1

2

Small-scale

0.479

High

953137

ACTB
Actin, cytoplasmic 1

1

3

Small-scale

0.479

High

959670

MAX
Protein max

1

3

Small-scale

0.479

High

993350

ACTG
Actin, cytoplasmic 2

1

3

Small-scale

0.479

High

998861

H31
Histone H3.1

1

1

High-throughput

0.479

High

1017247

H33
Histone H3.3

1

1

High-throughput

0.479

High

1129761

MDC1
Mediator of DNA damage checkpoint protein 1

1

1

High-throughput

0.479

High

1141331

BRD3
Bromodomain-containing protein 3

1

2

High-throughput

0.479

High

1163240

H2B2E
Histone H2B type 2-E

1

2

Small-scale

0.479

High

1253877

SRCAP
Helicase SRCAP

1

2

Small-scale

0.479

High

1259643

H2AV
Histone H2A.V

1

1

Small-scale

0.479

High

1278978

EMSY
BRCA2-interacting transcriptional repressor EMSY

1

2

High-throughput

0.479

High

1291985

JAZF1
Juxtaposed with another zinc finger protein 1

1

1

Small-scale

0.479

High

1367392

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

517123

NT2NC
Notch homolog 2 N-terminal-like protein C

1

1

High-throughput

0.470

High

1228915

MSL1
Male-specific lethal 1 homolog

1

0

Small-scale

0.460

High

316062

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.458

High

325128

HEXI1
Protein HEXIM1

1

0

High-throughput

0.458

High

386284

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

Small-scale

0.458

High

401569

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

581736

MYOD1
Myoblast determination protein 1

1

0

High-throughput

0.458

High

910705

HNRPM
Heterogeneous nuclear ribonucleoprotein M

1

0

Small-scale

0.458

High

965912

HNRPK
Heterogeneous nuclear ribonucleoprotein K

1

0

Small-scale

0.458

High

980414

H4
Histone H4

1

0

High-throughput

0.458

High

1027791

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

0

Small-scale

0.458

High

1045823

TF65
Transcription factor p65

1

0

High-throughput

0.458

High

1095312

REST
RE1-silencing transcription factor

1

0

High-throughput

0.458

High

1134405

IMB1
Importin subunit beta-1

1

0

Small-scale

0.458

High

1159025

RBBP7
Histone-binding protein RBBP7

1

0

Small-scale

0.458

High

1294962

PALB2
Partner and localizer of BRCA2

1

0

High-throughput

0.458

High

1357160

GATD1
GATA zinc finger domain-containing protein 1

1

0

High-throughput

0.458

High

1401052

PHF12
PHD finger protein 12

1

0

High-throughput

0.458

High

1450240

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1450242

NUP50
Nuclear pore complex protein Nup50

1

0

High-throughput

0.458

High

1450243

MED23
Mediator of RNA polymerase II transcription subunit 23

1

0

High-throughput

0.458

High

995845

ACTC
Actin, alpha cardiac muscle 1

1

3

High-throughput

0.437

High

996549

ACTS
Actin, alpha skeletal muscle

1

3

Small-scale

0.437

High

1393545

MR1L1
MORF4 family-associated protein 1-like 1

1

1

High-throughput

0.437

High

761523

HS71L
Heat shock 70 kDa protein 1-like

1

0

Small-scale

0.426

High

1394897

EAF1
ELL-associated factor 1

1

0

High-throughput

0.426

High

1194651

KCD21
BTB/POZ domain-containing protein KCTD21

2

0

High-throughput

0.328

High

1414970

CP250
Centrosome-associated protein CEP250

2

0

High-throughput

0.328

High

1418975

KR171
Keratin-associated protein 17-1

2

0

High-throughput

0.316

High

415889

HSPB1
Heat shock protein beta-1

1

0

High-throughput

0.282

High

706332

S10A2
Protein S100-A2

1

0

High-throughput

0.279

Low

1330781

UBR7
Putative E3 ubiquitin-protein ligase UBR7

1

0

High-throughput

0.279

Low

913681

VAV2
Guanine nucleotide exchange factor VAV2

1

0

High-throughput

0.265

Low

1450238

SH3B4
SH3 domain-binding protein 4

1

0

High-throughput

0.265

Low

643

NBPFJ
NBPF family member NBPF19

1

0

High-throughput

0.251

Low

459853

PMGE
Bisphosphoglycerate mutase

1

0

High-throughput

0.249

Low

1118614

TBB2A
Tubulin beta-2A chain

1

0

Small-scale

0.249

Low

1130723

DIP2A
Disco-interacting protein 2 homolog A

1

0

Small-scale

0.249

Low

1259533

TBA1A
Tubulin alpha-1A chain

1

0

Small-scale

0.249

Low

1410216

CMS1
Protein CMSS1

1

0

High-throughput

0.249

Low

1434018

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

1438318

PLAC1
Placenta-specific protein 1

1

0

High-throughput

0.249

Low

966931

1433G
14-3-3 protein gamma

1

0

High-throughput

0.232

Low

1335749

MOT11
Monocarboxylate transporter 11

1

0

High-throughput

0.232

Low

1437356

LN28A
Protein lin-28 homolog A

1

0

High-throughput

0.232

Low

1448758

PLS4
Phospholipid scramblase 4

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025