Protein: ZFY26
Zinc finger FYVE domain-containing protein 26 (FYVE domain-containing centrosomal protein) (FYVE-CENT) (Spastizin)

Gene: ZFY26, ZFYVE26
Organism: Homo sapiens
Interactions: 62
UniProt ID: Q68DK2

Gene Ontology (top 5):
GO:0000281 - mitotic cytokinesis
GO:0000724 - double-strand break repair via homologous recombination
GO:0005764 - lysosome
GO:0005765 - lysosomal membrane
GO:0005769 - early endosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1228889

PKHF2
Pleckstrin homology domain-containing family F member 2

2

13

High-throughput

0.783

High

1228888

CEP44
Centrosomal protein of 44 kDa

3

1

High-throughput

0.675

High

950289

KR107
Keratin-associated protein 10-7

3

7

High-throughput

0.616

High

1228867

K1C40
Keratin, type I cytoskeletal 40

3

20

High-throughput

0.616

High

1228873

USBP1
Harmonin-binding protein USHBP1

3

14

High-throughput

0.616

High

1228869

HMBX1
Homeobox-containing protein 1

2

4

High-throughput

0.606

High

1228882

HOOK2
Protein Hook homolog 2

2

17

High-throughput

0.606

High

1228890

PRDM6
Putative histone-lysine N-methyltransferase PRDM6

2

4

High-throughput

0.606

High

1228895

UBP20
Ubiquitin carboxyl-terminal hydrolase 20

2

3

High-throughput

0.606

High

770869

OPRM
Mu-type opioid receptor

2

4

High-throughput

0.574

High

1228885

PNMA5
Paraneoplastic antigen-like protein 5

2

4

High-throughput

0.573

High

1228892

TFP11
Tuftelin-interacting protein 11

2

2

High-throughput

0.573

High

283491

TAD2A
Transcriptional adapter 2-alpha

1

3

High-throughput

0.573

High

1063333

GOGA2
Golgin subfamily A member 2

1

18

High-throughput

0.573

High

1093851

TRAF1
TNF receptor-associated factor 1

1

5

High-throughput

0.573

High

300384

KRT34
Keratin, type I cuticular Ha4

2

20

High-throughput

0.553

High

1228870

K1C27
Keratin, type I cytoskeletal 27

2

20

High-throughput

0.553

High

1228872

CC125
Coiled-coil domain-containing protein 125

2

1

High-throughput

0.553

High

1228874

TEANC
Transcription elongation factor A N-terminal and central domain-containing protein

2

2

High-throughput

0.553

High

1228879

ASB15
Ankyrin repeat and SOCS box protein 15

2

4

High-throughput

0.553

High

1228883

PP16A
Protein phosphatase 1 regulatory subunit 16A

2

5

High-throughput

0.553

High

1228897

MAGD1
Melanoma-associated antigen D1

2

5

High-throughput

0.553

High

563907

CFTR
Cystic fibrosis transmembrane conductance regulator

1

4

High-throughput

0.541

High

1228880

RUBIC
Run domain Beclin-1-interacting and cysteine-rich domain-containing protein

1

2

High-throughput

0.536

High

462465

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

1

High-throughput

0.523

High

560876

HEM1
5-aminolevulinate synthase, non-specific, mitochondrial

1

1

High-throughput

0.523

High

618047

K1C15
Keratin, type I cytoskeletal 15

1

20

High-throughput

0.523

High

950794

KR109
Keratin-associated protein 10-9

1

7

High-throughput

0.523

High

1228876

PNMA1
Paraneoplastic antigen Ma1

1

4

High-throughput

0.523

High

1228891

AP5S1
AP-5 complex subunit sigma-1

1

0

High-throughput

0.513

High

1228886

SPAG5
Sperm-associated antigen 5

1

20

High-throughput

0.508

High

1228898

NPTN
Neuroplastin

1

9

High-throughput

0.489

High

1228894

ADIP
Afadin- and alpha-actinin-binding protein

1

0

High-throughput

0.486

High

562130

LAMP2
Lysosome-associated membrane glycoprotein 2

1

14

High-throughput

0.479

High

901874

RAB9A
Ras-related protein Rab-9A

1

20

High-throughput

0.479

High

1228868

LTOR1
Ragulator complex protein LAMTOR1

1

9

High-throughput

0.479

High

898484

PPT1
Palmitoyl-protein thioesterase 1

1

0

High-throughput

0.458

High

286376

DAB1
Disabled homolog 1

1

3

High-throughput

0.451

High

669335

ACKR3
Atypical chemokine receptor 3

1

8

High-throughput

0.445

High

949902

KR103
Keratin-associated protein 10-3

1

6

High-throughput

0.439

High

1228884

CC136
Coiled-coil domain-containing protein 136

1

20

High-throughput

0.439

High

139235

UPK2
Uroplakin-2

1

1

High-throughput

0.407

High

182584

GP182
G-protein coupled receptor 182

1

7

High-throughput

0.407

High

262246

SCN2B
Sodium channel regulatory subunit beta-2

1

5

High-throughput

0.407

High

638445

FPR1
fMet-Leu-Phe receptor

1

6

High-throughput

0.407

High

683257

TNR5
Tumor necrosis factor receptor superfamily member 5

1

6

High-throughput

0.407

High

704023

5HT1E
5-hydroxytryptamine receptor 1E

1

2

High-throughput

0.407

High

886072

CXCR3
C-X-C chemokine receptor type 3

1

7

High-throughput

0.407

High

1101521

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

8

High-throughput

0.407

High

1219492

ANR22
Ankyrin repeat domain-containing protein 22

1

5

High-throughput

0.407

High

1228871

P2RY8
S-geranylgeranyl-glutathione receptor P2RY8

1

7

High-throughput

0.407

High

1228877

DNJB8
DnaJ homolog subfamily B member 8

1

4

High-throughput

0.407

High

1228878

GTR12
Solute carrier family 2, facilitated glucose transporter member 12

1

1

High-throughput

0.407

High

1228893

FZD10
Frizzled-10

1

1

High-throughput

0.407

High

1228887

MDFI
MyoD family inhibitor

3

0

High-throughput

0.353

High

877746

T23O
Tryptophan 2,3-dioxygenase

3

0

High-throughput

0.352

High

1220004

TTC23
Tetratricopeptide repeat protein 23

2

0

High-throughput

0.316

High

1228875

CBY2
Protein chibby homolog 2

2

0

High-throughput

0.316

High

1228881

GASP2
G-protein coupled receptor-associated sorting protein 2

2

0

High-throughput

0.316

High

280927

HYPM
Huntingtin-interacting protein M

1

0

High-throughput

0.279

Low

1228896

FIS1
Mitochondrial fission 1 protein

1

0

High-throughput

0.279

Low

50582

HACL2
2-hydroxyacyl-CoA lyase 2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025