Protein: DTBP1
Dysbindin (Biogenesis of lysosome-related organelles complex 1 subunit 8) (BLOC-1 subunit 8) (Dysbindin-1) (Dystrobrevin-binding protein 1) (Hermansky-Pudlak syndrome 7 protein) (HPS7 protein)

Gene: DTBP1, DTNBP1
Organism: Homo sapiens
Interactions: 160
UniProt ID: Q96EV8

Gene Ontology (top 5):
GO:0001822 - kidney development
GO:0001934 - positive regulation of protein phosphorylation
GO:0001956 - positive regulation of neurotransmitter secretion
GO:0002092 - positive regulation of receptor internalization
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

310992

SNAPN
SNARE-associated protein Snapin

9

1

Small-scale

0.756

High

1290411

BL1S6
Biogenesis of lysosome-related organelles complex 1 subunit 6

8

1

Small-scale

0.754

High

944557

BL1S1
Biogenesis of lysosome-related organelles complex 1 subunit 1

5

1

Small-scale

0.716

High

1163365

BL1S2
Biogenesis of lysosome-related organelles complex 1 subunit 2

5

1

Small-scale

0.716

High

1232439

TXLNB
Beta-taxilin

4

1

High-throughput

0.707

High

1255020

BL1S5
Biogenesis of lysosome-related organelles complex 1 subunit 5

6

0

Small-scale

0.706

High

1254474

CCHCR
Coiled-coil alpha-helical rod protein 1

4

1

High-throughput

0.705

High

1023313

TRI32
E3 ubiquitin-protein ligase TRIM32

4

3

Small-scale

0.702

High

1290427

DTNA
Dystrobrevin alpha

4

6

Small-scale

0.698

High

1290403

BL1S4
Biogenesis of lysosome-related organelles complex 1 subunit 4

4

2

Small-scale

0.691

High

1163340

BL1S3
Biogenesis of lysosome-related organelles complex 1 subunit 3

5

0

Small-scale

0.686

High

1260581

BRK1
Protein BRICK1

4

0

High-throughput

0.675

High

1283620

EXOC4
Exocyst complex component 4

4

0

High-throughput

0.669

High

1290405

SYBU
Syntabulin

4

0

High-throughput

0.669

High

120016

AP3B1
AP-3 complex subunit beta-1

3

1

High-throughput

0.667

High

150251

AP3D1
AP-3 complex subunit delta-1

3

2

High-throughput

0.667

High

166763

CE290
Centrosomal protein of 290 kDa

3

2

High-throughput

0.667

High

264081

TACC1
Transforming acidic coiled-coil-containing protein 1

3

1

High-throughput

0.667

High

1017551

KIF5A
Kinesin heavy chain isoform 5A

3

2

High-throughput

0.667

High

1032734

AP3B2
AP-3 complex subunit beta-2

3

1

High-throughput

0.667

High

1224631

ABI1
Abl interactor 1

3

2

High-throughput

0.667

High

1224770

ASPM
Abnormal spindle-like microcephaly-associated protein

3

4

High-throughput

0.667

High

1251321

EXOC6
Exocyst complex component 6

3

1

High-throughput

0.667

High

1255101

BCAS4
Breast carcinoma-amplified sequence 4

3

1

High-throughput

0.667

High

1267480

AP3S1
AP-3 complex subunit sigma-1

3

2

High-throughput

0.667

High

1290383

CYFP2
Cytoplasmic FMR1-interacting protein 2

3

1

High-throughput

0.667

High

1290399

KLC2
Kinesin light chain 2

3

2

High-throughput

0.667

High

1290401

MYO5C
Unconventional myosin-Vc

3

1

High-throughput

0.667

High

1290424

KIF3A
Kinesin-like protein KIF3A

3

2

High-throughput

0.667

High

1290426

MYO5A
Unconventional myosin-Va

3

1

High-throughput

0.667

High

1290417

EXOC7
Exocyst complex component 7

4

0

High-throughput

0.665

High

1200188

TRI74
Tripartite motif-containing protein 74

3

1

High-throughput

0.657

High

246478

DTNB
Dystrobrevin beta

2

6

Small-scale

0.641

High

130092

EXOC5
Exocyst complex component 5

3

0

High-throughput

0.638

High

238000

EXOC3
Exocyst complex component 3

3

0

High-throughput

0.638

High

1132401

TEX35
Testis-expressed protein 35

3

0

High-throughput

0.638

High

1137637

VPS53
Vacuolar protein sorting-associated protein 53 homolog

3

0

High-throughput

0.638

High

1163021

TRAF7
E3 ubiquitin-protein ligase TRAF7

3

0

High-throughput

0.638

High

1199848

KTN1
Kinectin

3

0

High-throughput

0.638

High

1243672

NAV1
Neuron navigator 1

3

0

High-throughput

0.638

High

1286516

ENTR1
Endosome-associated-trafficking regulator 1

3

0

High-throughput

0.638

High

1290393

VAMP8
Vesicle-associated membrane protein 8

3

0

High-throughput

0.638

High

1290404

EXOC1
Exocyst complex component 1

3

0

High-throughput

0.638

High

1290407

VTI1B
Vesicle transport through interaction with t-SNAREs homolog 1B

3

0

High-throughput

0.638

High

1290408

VPS51
Vacuolar protein sorting-associated protein 51 homolog

3

0

High-throughput

0.638

High

1290414

STX8
Syntaxin-8

3

0

High-throughput

0.638

High

1290415

COG5
Conserved oligomeric Golgi complex subunit 5

3

0

High-throughput

0.638

High

1290419

NCKP1
Nck-associated protein 1

3

0

High-throughput

0.638

High

1290421

AP3M1
AP-3 complex subunit mu-1

3

0

High-throughput

0.638

High

1203441

TRI69
E3 ubiquitin-protein ligase TRIM69

2

1

High-throughput

0.628

High

1290390

NECD
Necdin

3

0

Small-scale

0.628

High

1221976

IFT20
Intraflagellar transport protein 20 homolog

2

0

High-throughput

0.616

High

673159

CCND3
G1/S-specific cyclin-D3

2

3

Small-scale

0.614

High

241796

CCD22
Coiled-coil domain-containing protein 22

2

1

High-throughput

0.611

High

702961

KINH
Kinesin-1 heavy chain

2

2

High-throughput

0.611

High

992380

KLC1
Kinesin light chain 1

2

2

High-throughput

0.611

High

1040044

IQGA2
Ras GTPase-activating-like protein IQGAP2

2

2

High-throughput

0.611

High

1184643

CYFP1
Cytoplasmic FMR1-interacting protein 1

2

1

High-throughput

0.611

High

1290420

EXC6B
Exocyst complex component 6B

3

1

High-throughput

0.609

High

1290409

TSKS
Testis-specific serine kinase substrate

2

0

High-throughput

0.602

High

1290410

GGA1
ADP-ribosylation factor-binding protein GGA1

2

0

High-throughput

0.602

High

1255297

MIPT3
TRAF3-interacting protein 1

2

0

High-throughput

0.588

High

171160

CETN3
Centrin-3

2

0

High-throughput

0.585

High

1027540

STX5
Syntaxin-5

2

0

High-throughput

0.585

High

1033907

SNTB2
Beta-2-syntrophin

2

0

High-throughput

0.585

High

1290387

SPAG5
Sperm-associated antigen 5

2

0

High-throughput

0.585

High

1290392

BBLN
Bublin coiled-coil protein

2

0

High-throughput

0.585

High

204410

MS18B
Protein Mis18-beta

2

0

High-throughput

0.580

High

318862

K2C75
Keratin, type II cytoskeletal 75

2

0

High-throughput

0.580

High

1191776

NECA2
N-terminal EF-hand calcium-binding protein 2

2

0

High-throughput

0.580

High

1205048

VRK2
Serine/threonine-protein kinase VRK2

1

4

Small-scale

0.578

High

536979

TRI27
Zinc finger protein RFP

1

1

High-throughput

0.573

High

1290394

KIFC3
Kinesin-like protein KIFC3

1

2

High-throughput

0.573

High

622506

CCND1
G1/S-specific cyclin-D1

1

3

Small-scale

0.561

High

1100988

RN151
RING finger protein 151

1

3

Small-scale

0.561

High

50786

ELOV7
Very long chain fatty acid elongase 7

1

0

High-throughput

0.549

High

50869

SRCRL
Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D

1

0

High-throughput

0.549

High

132985

SDCB1
Syntenin-1

1

0

High-throughput

0.549

High

1188178

KANL1
KAT8 regulatory NSL complex subunit 1

1

0

High-throughput

0.549

High

1223041

CC146
Coiled-coil domain-containing protein 146

1

0

High-throughput

0.549

High

1287078

HAUS1
HAUS augmin-like complex subunit 1

1

0

High-throughput

0.549

High

1290402

SHFL
Shiftless antiviral inhibitor of ribosomal frameshifting protein

1

0

High-throughput

0.549

High

1290406

ABI3
ABI gene family member 3

1

2

High-throughput

0.541

High

230518

TRAK2
Trafficking kinesin-binding protein 2

1

1

High-throughput

0.536

High

1159994

KLC3
Kinesin light chain 3

1

2

High-throughput

0.536

High

1189628

K1C27
Keratin, type I cytoskeletal 27

1

1

High-throughput

0.536

High

1237104

TRIMM
Probable E3 ubiquitin-protein ligase TRIML2

1

2

High-throughput

0.536

High

862190

ARFP2
Arfaptin-2

1

0

High-throughput

0.518

High

1290395

DGC6L
Protein DGCR6L

1

0

High-throughput

0.518

High

305021

DUS14
Dual specificity protein phosphatase 14

1

0

High-throughput

0.513

High

814106

IF1AX
Eukaryotic translation initiation factor 1A, X-chromosomal

1

0

High-throughput

0.513

High

930957

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

0

High-throughput

0.513

High

1028270

SBP1
Methanethiol oxidase

1

0

High-throughput

0.513

High

1154382

HPHL1
Ferroxidase HEPHL1

1

0

High-throughput

0.513

High

1197756

DSG4
Desmoglein-4

1

0

High-throughput

0.513

High

1257238

LRC15
Leucine-rich repeat-containing protein 15

1

0

High-throughput

0.513

High

1022796

AKAP6
A-kinase anchor protein 6

1

5

High-throughput

0.508

High

1290416

MACF1
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5

1

4

High-throughput

0.508

High

660869

PTPRM
Receptor-type tyrosine-protein phosphatase mu

1

0

High-throughput

0.493

High

1290389

OSBL9
Oxysterol-binding protein-related protein 9

1

0

High-throughput

0.493

High

127342

IPO5
Importin-5

1

0

High-throughput

0.486

High

590215

CCNA2
Cyclin-A2

1

0

High-throughput

0.486

High

898998

PSME3
Proteasome activator complex subunit 3

1

0

High-throughput

0.486

High

914278

RB11A
Ras-related protein Rab-11A

1

0

High-throughput

0.486

High

1204492

SFR1
Swi5-dependent recombination DNA repair protein 1 homolog

1

0

High-throughput

0.486

High

1244923

NBEA
Neurobeachin

1

0

High-throughput

0.486

High

1273552

TF3B
Transcription factor IIIB 90 kDa subunit

1

0

High-throughput

0.486

High

1290400

RBNS5
Rabenosyn-5

1

0

High-throughput

0.486

High

1290412

ZN490
Zinc finger protein 490

1

0

High-throughput

0.486

High

224722

KALRN
Kalirin

1

2

High-throughput

0.481

High

974129

DYST
Dystonin

1

4

High-throughput

0.481

High

1244122

SYNE1
Nesprin-1

1

5

High-throughput

0.481

High

1290396

NUF2
Kinetochore protein Nuf2

1

2

High-throughput

0.481

High

1290397

TRIM9
E3 ubiquitin-protein ligase TRIM9

1

5

High-throughput

0.481

High

1290398

TRIM2
Tripartite motif-containing protein 2

1

4

High-throughput

0.481

High

310075

TNKS1
Poly [ADP-ribose] polymerase tankyrase-1

1

0

High-throughput

0.480

High

170446

TIF1A
Transcription intermediary factor 1-alpha

1

2

Small-scale

0.479

High

317323

PCNT
Pericentrin

1

1

High-throughput

0.479

High

557768

NCK1
SH2/SH3 adapter protein NCK1

1

1

High-throughput

0.479

High

655442

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

1

High-throughput

0.479

High

673094

CCND2
G1/S-specific cyclin-D2

1

3

Small-scale

0.479

High

887147

AP3S2
AP-3 complex subunit sigma-2

1

1

High-throughput

0.479

High

1253986

ALMS1
Centrosome-associated protein ALMS1

1

2

High-throughput

0.479

High

1290388

CK5P2
CDK5 regulatory subunit-associated protein 2

1

1

High-throughput

0.479

High

200224

SRGP3
SLIT-ROBO Rho GTPase-activating protein 3

1

0

High-throughput

0.460

High

1051399

DCTN1
Dynactin subunit 1

1

0

High-throughput

0.460

High

163128

XPO1
Exportin-1

1

0

High-throughput

0.458

High

228335

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

581039

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

1

0

High-throughput

0.458

High

632351

TNR6
Tumor necrosis factor receptor superfamily member 6

1

0

High-throughput

0.458

High

847872

BRCA2
Breast cancer type 2 susceptibility protein

1

0

High-throughput

0.458

High

1152031

LTOR1
Ragulator complex protein LAMTOR1

1

0

High-throughput

0.458

High

1170133

FA83H
Protein FAM83H

1

0

High-throughput

0.458

High

1290425

DCAF1
DDB1- and CUL4-associated factor 1

1

0

High-throughput

0.458

High

1290428

BIG2
Brefeldin A-inhibited guanine nucleotide-exchange protein 2

1

0

High-throughput

0.458

High

980119

ATP7A
Copper-transporting ATPase 1

1

0

Small-scale

0.426

High

1124782

Q5BKU8
SYNE1 protein

1

7

High-throughput

0.417

High

1290385

BORC6
BLOC-1-related complex subunit 6

4

0

High-throughput

0.362

High

949235

COG7
Conserved oligomeric Golgi complex subunit 7

3

0

High-throughput

0.347

High

1045116

LAMC2
Laminin subunit gamma-2

3

0

High-throughput

0.347

High

1121540

EIPR1
EARP and GARP complex-interacting protein 1

3

0

High-throughput

0.347

High

1290384

BORC8
BLOC-1-related complex subunit 8

3

0

High-throughput

0.347

High

1290386

VPS50
Syndetin

3

0

High-throughput

0.347

High

1290391

KXDL1
KxDL motif-containing protein 1

3

0

High-throughput

0.347

High

1290413

SNX7
Sorting nexin-7

3

0

High-throughput

0.347

High

1290422

COG6
Conserved oligomeric Golgi complex subunit 6

3

0

High-throughput

0.347

High

1290423

WASC3
WASH complex subunit 3

2

0

High-throughput

0.335

High

1132682

AKND1
Protein AKNAD1

2

0

High-throughput

0.324

High

1115319

DRC12
Dynein regulatory complex protein 12

1

0

High-throughput

0.299

High

1190502

P4HA3
Prolyl 4-hydroxylase subunit alpha-3

1

0

High-throughput

0.299

High

1070024

PWP2
Periodic tryptophan protein 2 homolog

1

0

High-throughput

0.279

Low

1159565

TTC27
Tetratricopeptide repeat protein 27

1

0

High-throughput

0.279

Low

1197704

LYG2
Lysozyme g-like protein 2

1

0

High-throughput

0.279

Low

1290418

ANGP4
Angiopoietin-4

1

0

High-throughput

0.279

Low

1149589

BICRL
BRD4-interacting chromatin-remodeling complex-associated protein-like

1

0

High-throughput

0.265

Low

1172617

K0408
Uncharacterized protein KIAA0408

1

0

High-throughput

0.265

Low

557339

GDC
Solute carrier family 25 member 16

1

0

High-throughput

0.249

Low

484324

VSIG8
V-set and immunoglobulin domain-containing protein 8

1

0

High-throughput

0.232

Low

1091157

WHAL1
Putative WASP homolog-associated protein with actin, membranes and microtubules-like protein 1

1

0

High-throughput

0.232

Low

1126407

NHSL2
NHS-like protein 2

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024