Protein: TTC23
Tetratricopeptide repeat protein 23 (TPR repeat protein 23) (Cervical cancer proto-oncogene 8 protein) (HCC-8)

Gene: TTC23
Organism: Homo sapiens
Interactions: 118
UniProt ID: Q5W5X9

Gene Ontology (top 5):
GO:0005929 - cilium
GO:0045880 - positive regulation of smoothened signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1220006

IQCE
IQ domain-containing protein E

3

3

High-throughput

0.665

High

1169068

INSC
Protein inscuteable homolog

2

0

High-throughput

0.655

High

1063328

GOGA2
Golgin subfamily A member 2

3

2

High-throughput

0.616

High

1145979

K1H1
Keratin, type I cuticular Ha1

3

14

High-throughput

0.616

High

1220039

LZTS2
Leucine zipper putative tumor suppressor 2

3

2

High-throughput

0.616

High

1220042

TRI54
Tripartite motif-containing protein 54

3

4

High-throughput

0.616

High

1205819

MTUS2
Microtubule-associated tumor suppressor candidate 2

3

2

High-throughput

0.593

High

1220038

SPAG8
Sperm-associated antigen 8

2

0

High-throughput

0.580

High

1220057

TRI10
Tripartite motif-containing protein 10

2

1

High-throughput

0.573

High

51431

FSD2
Fibronectin type III and SPRY domain-containing protein 2

2

3

High-throughput

0.553

High

65067

GG6L9
Golgin subfamily A member 6-like protein 9

2

3

High-throughput

0.553

High

300379

KRT34
Keratin, type I cuticular Ha4

2

14

High-throughput

0.553

High

300578

KRT36
Keratin, type I cuticular Ha6

2

13

High-throughput

0.553

High

476335

K1C16
Keratin, type I cytoskeletal 16

2

13

High-throughput

0.553

High

618045

K1C15
Keratin, type I cytoskeletal 15

2

14

High-throughput

0.553

High

833293

PERI
Peripherin

2

7

High-throughput

0.553

High

950526

KR108
Keratin-associated protein 10-8

2

1

High-throughput

0.553

High

1007936

PO6F2
POU domain, class 6, transcription factor 2

2

1

High-throughput

0.553

High

1090708

TRAF2
TNF receptor-associated factor 2

2

1

High-throughput

0.553

High

1093366

TRI32
E3 ubiquitin-protein ligase TRIM32

2

3

High-throughput

0.553

High

1187632

T10IP
Testis-specific protein 10-interacting protein

2

1

High-throughput

0.553

High

1196261

GRAP1
GRIP1-associated protein 1

2

2

High-throughput

0.553

High

1201835

PKHG4
Puratrophin-1

2

1

High-throughput

0.553

High

1220003

C102B
Coiled-coil domain-containing protein 102B

2

1

High-throughput

0.553

High

1220008

K1C27
Keratin, type I cytoskeletal 27

2

11

High-throughput

0.553

High

1220018

CCD24
Coiled-coil domain-containing protein 24

2

1

High-throughput

0.553

High

1220019

KASH5
Protein KASH5

2

1

High-throughput

0.553

High

1220020

USBP1
Harmonin-binding protein USHBP1

2

1

High-throughput

0.553

High

1220023

PNMA1
Paraneoplastic antigen Ma1

2

1

High-throughput

0.553

High

1220030

HOOK2
Protein Hook homolog 2

2

2

High-throughput

0.553

High

1220032

F161B
Protein FAM161B

2

1

High-throughput

0.553

High

1220050

PICK1
PRKCA-binding protein

2

1

High-throughput

0.553

High

1220054

AIRIM
AFG2-interacting ribosome maturation factor

2

1

High-throughput

0.553

High

1220056

KLH42
Kelch-like protein 42

2

1

High-throughput

0.553

High

1220061

TRIM1
Probable E3 ubiquitin-protein ligase MID2

2

3

High-throughput

0.553

High

69702

EFCB7
EF-hand calcium-binding domain-containing protein 7

1

1

High-throughput

0.536

High

1220005

K1C40
Keratin, type I cytoskeletal 40

1

13

High-throughput

0.523

High

1220017

CNTRB
Centrobin

1

1

High-throughput

0.523

High

1220033

PNMA5
Paraneoplastic antigen-like protein 5

1

1

High-throughput

0.523

High

1220034

SPAG5
Sperm-associated antigen 5

1

2

High-throughput

0.523

High

1220024

MNS1
Meiosis-specific nuclear structural protein 1

1

0

High-throughput

0.493

High

1220045

ENKD1
Enkurin domain-containing protein 1

1

0

High-throughput

0.493

High

451180

NFL
Neurofilament light polypeptide

1

7

High-throughput

0.470

High

1220010

TRI74
Tripartite motif-containing protein 74

1

3

High-throughput

0.470

High

1220046

RPB1C
DNA-directed RNA polymerase II subunit RPB11-b2

1

1

High-throughput

0.470

High

949900

KR103
Keratin-associated protein 10-3

1

1

High-throughput

0.439

High

1220011

TRI73
Tripartite motif-containing protein 73

1

3

High-throughput

0.439

High

1220043

RPB1B
DNA-directed RNA polymerase II subunit RPB11-b1

1

1

High-throughput

0.439

High

343764

LDOC1
Protein LDOC1

4

0

High-throughput

0.364

High

1220037

MDFI
MyoD family inhibitor

3

0

High-throughput

0.352

High

1220052

ZHANG
CREB/ATF bZIP transcription factor

3

0

High-throughput

0.352

High

1220063

MAGD1
Melanoma-associated antigen D1

3

0

High-throughput

0.352

High

843651

HD
Huntingtin

2

0

High-throughput

0.327

High

70273

CRTP1
Cysteine-rich tail protein 1

2

0

High-throughput

0.316

High

70971

NOTO
Homeobox protein notochord

2

0

High-throughput

0.316

High

74344

ZBT42
Zinc finger and BTB domain-containing protein 42

2

0

High-throughput

0.316

High

225608

AAKB2
5'-AMP-activated protein kinase subunit beta-2

2

0

High-throughput

0.316

High

246671

KDM1A
Lysine-specific histone demethylase 1A

2

0

High-throughput

0.316

High

269237

HSF2B
Heat shock factor 2-binding protein

2

0

High-throughput

0.316

High

292359

RA51D
DNA repair protein RAD51 homolog 4

2

0

High-throughput

0.316

High

295986

TPC6A
Trafficking protein particle complex subunit 6A

2

0

High-throughput

0.316

High

331510

SPDEF
SAM pointed domain-containing Ets transcription factor

2

0

High-throughput

0.316

High

350469

GPAN1
G patch domain and ankyrin repeat-containing protein 1

2

0

High-throughput

0.316

High

352163

MBD3
Methyl-CpG-binding domain protein 3

2

0

High-throughput

0.316

High

354231

ZBED1
E3 SUMO-protein ligase ZBED1

2

0

High-throughput

0.316

High

1009664

NGAL
Neutrophil gelatinase-associated lipocalin

2

0

High-throughput

0.316

High

1022731

XIAP
E3 ubiquitin-protein ligase XIAP

2

0

High-throughput

0.316

High

1033370

CDR2
Cerebellar degeneration-related protein 2

2

0

High-throughput

0.316

High

1051380

ZBT16
Zinc finger and BTB domain-containing protein 16

2

0

High-throughput

0.316

High

1057620

CDK18
Cyclin-dependent kinase 18

2

0

High-throughput

0.316

High

1061739

TLE5
TLE family member 5

2

0

High-throughput

0.316

High

1064634

SG11B
Sperm-associated antigen 11B

2

0

High-throughput

0.316

High

1093637

MKRN3
E3 ubiquitin-protein ligase makorin-3

2

0

High-throughput

0.316

High

1131183

MESD
LRP chaperone MESD

2

0

High-throughput

0.316

High

1151536

TRIP6
Thyroid receptor-interacting protein 6

2

0

High-throughput

0.316

High

1155967

ZFHX3
Zinc finger homeobox protein 3

2

0

High-throughput

0.316

High

1211739

UBX11
UBX domain-containing protein 11

2

0

High-throughput

0.316

High

1220004

ZFY26
Zinc finger FYVE domain-containing protein 26

2

0

High-throughput

0.316

High

1220009

K1328
Protein hinderin

2

0

High-throughput

0.316

High

1220014

MD12L
Mediator of RNA polymerase II transcription subunit 12-like protein

2

0

High-throughput

0.316

High

1220016

ABI1
Abl interactor 1

2

0

High-throughput

0.316

High

1220021

EFCB3
EF-hand calcium-binding domain-containing protein 3

2

0

High-throughput

0.316

High

1220022

BANP
Protein BANP

2

0

High-throughput

0.316

High

1220025

ADCY4
Adenylate cyclase type 4

2

0

High-throughput

0.316

High

1220028

PIHD2
PIH1 domain-containing protein 2

2

0

High-throughput

0.316

High

1220029

GASP2
G-protein coupled receptor-associated sorting protein 2

2

0

High-throughput

0.316

High

1220031

PP16A
Protein phosphatase 1 regulatory subunit 16A

2

0

High-throughput

0.316

High

1220035

TRIB3
Tribbles homolog 3

2

0

High-throughput

0.316

High

1220040

TX13A
Testis-expressed protein 13A

2

0

High-throughput

0.316

High

1220041

HOIL1
RanBP-type and C3HC4-type zinc finger-containing protein 1

2

0

High-throughput

0.316

High

1220044

XRN2
5'-3' exoribonuclease 2

2

0

High-throughput

0.316

High

1220047

GO45
Golgin-45

2

0

High-throughput

0.316

High

1220048

CBX8
Chromobox protein homolog 8

2

0

High-throughput

0.316

High

1220049

PRDM6
Putative histone-lysine N-methyltransferase PRDM6

2

0

High-throughput

0.316

High

1220051

DISC1
Disrupted in schizophrenia 1 protein

2

0

High-throughput

0.316

High

1220055

ZIM2
Zinc finger imprinted 2

2

0

High-throughput

0.316

High

1220060

PS1C2
Psoriasis susceptibility 1 candidate gene 2 protein

2

0

High-throughput

0.316

High

154995

BHE40
Class E basic helix-loop-helix protein 40

1

0

High-throughput

0.299

High

283490

TAD2A
Transcriptional adapter 2-alpha

1

0

High-throughput

0.299

High

332517

CCDB1
Cyclin-D1-binding protein 1

1

0

High-throughput

0.299

High

560875

HEM1
5-aminolevulinate synthase, non-specific, mitochondrial

1

0

High-throughput

0.299

High

1220062

ADIP
Afadin- and alpha-actinin-binding protein

1

0

High-throughput

0.299

High

1220015

ZDH17
Palmitoyltransferase ZDHHC17

1

0

High-throughput

0.282

High

301476

WFS1
Wolframin

1

0

High-throughput

0.268

Low

705400

GRN
Progranulin

1

0

High-throughput

0.268

Low

896788

DYN2
Dynamin-2

1

0

High-throughput

0.268

Low

935531

MFAP1
Microfibrillar-associated protein 1

1

0

High-throughput

0.268

Low

954500

PRPS1
Ribose-phosphate pyrophosphokinase 1

1

0

High-throughput

0.268

Low

1220007

NSMF
NMDA receptor synaptonuclear signaling and neuronal migration factor

1

0

High-throughput

0.268

Low

1220012

ZN410
Zinc finger protein 410

1

0

High-throughput

0.268

Low

1220026

ZN417
Zinc finger protein 417

1

0

High-throughput

0.268

Low

1220027

MIPO1
Mirror-image polydactyly gene 1 protein

1

0

High-throughput

0.268

Low

1220036

PRP18
Pre-mRNA-splicing factor 18

1

0

High-throughput

0.268

Low

1220053

FANCL
E3 ubiquitin-protein ligase FANCL

1

0

High-throughput

0.268

Low

1220059

CTNA3
Catenin alpha-3

1

0

High-throughput

0.268

Low

422300

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.261

Low

1220013

NUTM1
NUT family member 1

1

0

High-throughput

0.251

Low

1220058

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.251

Low


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Last updated: 11Aug2025