Protein: TNFB
Lymphotoxin-alpha (LT-alpha) (TNF-beta) (Tumor necrosis factor ligand superfamily member 1)

Gene: TNFB, LTA
Organism: Homo sapiens
Interactions: 30
UniProt ID: P01374

Gene Ontology (top 5):
GO:0001666 - response to hypoxia
GO:0002876 - positive regulation of chronic inflammatory response to antigenic stimulus
GO:0002925 - positive regulation of humoral immune response mediated by circulating immunoglobulin
GO:0005102 - signaling receptor binding
GO:0005125 - cytokine activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

377881

TNR1A
Tumor necrosis factor receptor superfamily member 1A

6

20

Small-scale

0.942

High

377886

TNFC
Lymphotoxin-beta

5

8

Small-scale

0.924

High

377882

TNR1B
Tumor necrosis factor receptor superfamily member 1B

3

20

Small-scale

0.858

High

377894

TNR14
Tumor necrosis factor receptor superfamily member 14

2

20

Small-scale

0.754

High

377897

ZNT2
Proton-coupled zinc antiporter SLC30A2

3

2

High-throughput

0.654

High

377875

TNFB
Lymphotoxin-alpha

1

8

Small-scale

0.647

High

377876

TNFA
Tumor necrosis factor

1

8

Small-scale

0.618

High

377883

TNR3
Tumor necrosis factor receptor superfamily member 3

1

20

Small-scale

0.618

High

377893

TBA1A
Tubulin alpha-1A chain

2

6

Small-scale

0.611

High

377887

ASPH
Aspartyl/asparaginyl beta-hydroxylase

2

0

High-throughput

0.580

High

377895

TM237
Transmembrane protein 237

2

0

High-throughput

0.580

High

377877

LEG2
Galectin-2

1

1

Small-scale

0.538

High

377880

BIP
Endoplasmic reticulum chaperone BiP

1

2

High-throughput

0.536

High

377884

ACTB
Actin, cytoplasmic 1

1

7

High-throughput

0.536

High

230234

CREB3
Cyclic AMP-responsive element-binding protein 3

2

5

High-throughput

0.526

High

377879

UROM
Uromodulin

1

2

Small-scale

0.501

High

377878

TBB5
Tubulin beta chain

1

4

High-throughput

0.489

High

377890

TBB8
Tubulin beta-8 chain

1

4

High-throughput

0.489

High

377896

TBA1C
Tubulin alpha-1C chain

1

6

High-throughput

0.489

High

377900

DD19B
ATP-dependent RNA helicase DDX19B

1

4

High-throughput

0.489

High

58783

PIPSL
Putative PIP5K1A and PSMD4-like protein

1

1

High-throughput

0.445

High

377888

BIRC2
Baculoviral IAP repeat-containing protein 2

1

6

Small-scale

0.445

High

377889

RIPK1
Receptor-interacting serine/threonine-protein kinase 1

1

8

Small-scale

0.445

High

377885

TBA1B
Tubulin alpha-1B chain

1

6

Small-scale

0.437

High

377899

CLSPN
Claspin

1

1

Small-scale

0.437

High

377892

ANR40
Ankyrin repeat domain-containing protein 40

2

0

High-throughput

0.324

High

350337

ABHGA
Phosphatidylserine lipase ABHD16A

2

0

High-throughput

0.316

High

377891

HEAT6
HEAT repeat-containing protein 6

1

0

High-throughput

0.279

Low

377898

HDHD5
Haloacid dehalogenase-like hydrolase domain-containing 5

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025