Protein: CXCR1
C-X-C chemokine receptor type 1 (CXC-R1) (CXCR-1) (CDw128a) (High affinity interleukin-8 receptor A) (IL-8R A) (IL-8 receptor type 1) (CD antigen CD181)

Gene: CXCR1
Organism: Homo sapiens
Interactions: 19
UniProt ID: P25024

Gene Ontology (top 5):
GO:0002407 - dendritic cell chemotaxis
GO:0004918 - interleukin-8 receptor activity
GO:0004930 - G protein-coupled receptor activity
GO:0004950 - chemokine receptor activity
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

518765

IL8
Interleukin-8

12

20

Small-scale

0.978

High

418597

GNAI2
Guanine nucleotide-binding protein G(i) subunit alpha-2

2

19

Small-scale

0.754

High

668189

CXCL5
C-X-C motif chemokine 5

2

20

Small-scale

0.754

High

668187

CXCR1
C-X-C chemokine receptor type 1

1

18

Small-scale

0.665

High

443190

CDK1
Cyclin-dependent kinase 1

1

1

High-throughput

0.625

High

390320

CXCL7
Platelet basic protein

1

20

Small-scale

0.618

High

480486

GROA
Growth-regulated alpha protein

1

20

Small-scale

0.618

High

668188

CXCR2
C-X-C chemokine receptor type 2

1

18

Small-scale

0.618

High

668190

CXCL6
C-X-C motif chemokine 6

1

20

Small-scale

0.618

High

665948

IBP5
Insulin-like growth factor-binding protein 5

2

3

High-throughput

0.553

High

668195

FATE1
Fetal and adult testis-expressed transcript protein

2

1

High-throughput

0.553

High

668192

TBA1A
Tubulin alpha-1A chain

1

4

High-throughput

0.541

High

144165

UBE2C
Ubiquitin-conjugating enzyme E2 C

1

0

High-throughput

0.518

High

668194

PDC6I
Programmed cell death 6-interacting protein

1

3

High-throughput

0.494

High

668193

TARG1
Trafficking regulator of GLUT4 1

1

9

High-throughput

0.481

High

63636

A5PKU2
TUSC5 protein

1

9

High-throughput

0.470

High

668191

LASP1
LIM and SH3 domain protein 1

1

5

Small-scale

0.437

High

668196

CLDN1
Claudin domain-containing protein 1

2

0

High-throughput

0.316

High


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Last updated: 11Aug2025