Protein: CLDN1
Claudin domain-containing protein 1 (Claudin-25) (Membrane protein GENX-3745)

Gene: CLDN1, CLDND1
Organism: Homo sapiens
Interactions: 82
UniProt ID: Q9NY35

Gene Ontology (top 5):
GO:0009986 - cell surface
GO:0016324 - apical plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1279129

GOGA7
Golgin subfamily A member 7

5

1

High-throughput

0.654

High

1351537

HAVR2
Hepatitis A virus cellular receptor 2

3

0

High-throughput

0.634

High

755429

MA1A1
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA

4

1

High-throughput

0.630

High

1420738

ZDHC5
Palmitoyltransferase ZDHHC5

4

2

High-throughput

0.630

High

1452227

ZDHC8
Palmitoyltransferase ZDHHC8

4

2

High-throughput

0.630

High

1446630

C1QR1
Complement component C1q receptor

2

1

High-throughput

0.628

High

249268

MA1A2
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB

3

1

High-throughput

0.609

High

787258

BMR1A
Bone morphogenetic protein receptor type-1A

3

1

High-throughput

0.609

High

1446366

ZDHC4
Palmitoyltransferase ZDHHC4

2

2

High-throughput

0.553

High

787351

ACV1B
Activin receptor type-1B

1

1

High-throughput

0.536

High

1286579

AGRG6
Adhesion G-protein coupled receptor G6

1

1

High-throughput

0.536

High

163362

TR10B
Tumor necrosis factor receptor superfamily member 10B

1

0

High-throughput

0.513

High

922845

ITA8
Integrin alpha-8 [Cleaved into: Integrin alpha-8 heavy chain; Integrin alpha-8 light chain]

1

0

High-throughput

0.513

High

1177250

MICA
MHC class I polypeptide-related sequence A

1

0

High-throughput

0.513

High

522746

PTPRF
Receptor-type tyrosine-protein phosphatase F

1

2

High-throughput

0.489

High

658937

PTPRD
Receptor-type tyrosine-protein phosphatase delta

1

2

High-throughput

0.489

High

878105

AGRE5
Adhesion G protein-coupled receptor E5

1

1

High-throughput

0.489

High

1180210

GOG7B
Golgin subfamily A member 7B

1

1

High-throughput

0.489

High

126833

RHOD
Rho-related GTP-binding protein RhoD

1

7

High-throughput

0.437

High

601469

RHOQ
Rho-related GTP-binding protein RhoQ

1

5

High-throughput

0.437

High

953705

RAC3
Ras-related C3 botulinum toxin substrate 3

1

5

High-throughput

0.437

High

955672

CDC42
Cell division control protein 42 homolog

1

5

High-throughput

0.437

High

962556

RHOA
Transforming protein RhoA

1

5

High-throughput

0.437

High

988760

RAC1
Ras-related C3 botulinum toxin substrate 1

1

5

High-throughput

0.437

High

1015846

RHOG
Rho-related GTP-binding protein RhoG

1

5

High-throughput

0.437

High

1438192

RHOF
Rho-related GTP-binding protein RhoF

1

7

High-throughput

0.437

High

609822

LEG3
Galectin-3

1

0

High-throughput

0.426

High

1366276

LPAR1
Lysophosphatidic acid receptor 1

1

0

High-throughput

0.426

High

248794

PEPL
Periplakin

1

1

High-throughput

0.407

High

424560

PAI2
Plasminogen activator inhibitor 2

1

2

High-throughput

0.407

High

787717

SPB5
Serpin B5

1

2

High-throughput

0.407

High

1102765

PTPRS
Receptor-type tyrosine-protein phosphatase S

1

2

High-throughput

0.407

High

1281275

TMED4
Transmembrane emp24 domain-containing protein 4

1

1

High-throughput

0.407

High

1369020

EVPL
Envoplakin

1

1

High-throughput

0.407

High

1452226

SPB13
Serpin B13

1

2

High-throughput

0.407

High

1452229

TMED3
Transmembrane emp24 domain-containing protein 3

1

1

High-throughput

0.407

High

251164

B4GT4
Beta-1,4-galactosyltransferase 4

4

0

High-throughput

0.360

High

1315490

K2013
Uncharacterized protein KIAA2013

4

0

High-throughput

0.360

High

189879

STX7
Syntaxin-7

3

0

High-throughput

0.347

High

332714

LYPD3
Ly6/PLAUR domain-containing protein 3

3

0

High-throughput

0.347

High

1155196

EREP1
Endosomal transmembrane epsin interactor 1

3

0

High-throughput

0.347

High

1315411

TEFF1
Tomoregulin-1

3

0

High-throughput

0.347

High

338715

VNN2
Pantetheine hydrolase VNN2

2

0

High-throughput

0.328

High

357864

CYB
Cytochrome b

2

0

High-throughput

0.328

High

1336041

CTL5
Choline transporter-like protein 5

2

0

High-throughput

0.328

High

1366720

ALG3
Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase

2

0

High-throughput

0.318

High

668196

CXCR1
C-X-C chemokine receptor type 1

2

0

High-throughput

0.316

High

1419992

GPR61
G-protein coupled receptor 61

2

0

High-throughput

0.316

High

388317

GLPA
Glycophorin-A

2

0

High-throughput

0.313

High

572478

DRD2
D(2) dopamine receptor

1

0

High-throughput

0.282

High

880972

MTR1B
Melatonin receptor type 1B

1

0

High-throughput

0.282

High

174127

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

0

High-throughput

0.279

Low

226229

STX6
Syntaxin-6

1

0

High-throughput

0.279

Low

642304

COMT
Catechol O-methyltransferase

1

0

High-throughput

0.279

Low

658784

JAK1
Tyrosine-protein kinase JAK1

1

0

High-throughput

0.279

Low

894444

MMP14
Matrix metalloproteinase-14

1

0

High-throughput

0.279

Low

1031566

IFM3
Interferon-induced transmembrane protein 3

1

0

High-throughput

0.279

Low

1063020

DDR1
Epithelial discoidin domain-containing receptor 1

1

0

High-throughput

0.279

Low

1125938

GNA13
Guanine nucleotide-binding protein subunit alpha-13

1

0

High-throughput

0.279

Low

1213717

LRAD1
Low-density lipoprotein receptor class A domain-containing protein 1

1

0

High-throughput

0.279

Low

1253806

QSOX2
Sulfhydryl oxidase 2

1

0

High-throughput

0.279

Low

1327316

FBCD1
Fibrinogen C domain-containing protein 1

1

0

High-throughput

0.279

Low

1331204

F241A
Uncharacterized protein FAM241A

1

0

High-throughput

0.279

Low

1333615

SIDT2
SID1 transmembrane family member 2

1

0

High-throughput

0.279

Low

1334595

RN149
E3 ubiquitin-protein ligase RNF149

1

0

High-throughput

0.279

Low

1352538

GPX8
Probable glutathione peroxidase 8

1

0

High-throughput

0.279

Low

1391522

BSCL2
Seipin

1

0

High-throughput

0.279

Low

1392186

RUSF1
RUS family member 1

1

0

High-throughput

0.279

Low

1402473

MYADM
Myeloid-associated differentiation marker

1

0

High-throughput

0.279

Low

1413678

P4K2A
Phosphatidylinositol 4-kinase type 2-alpha

1

0

High-throughput

0.279

Low

1428297

PITH1
PITH domain-containing protein 1

1

0

High-throughput

0.279

Low

1438488

RXFP1
Relaxin receptor 1

1

0

High-throughput

0.279

Low

1450627

ARL8B
ADP-ribosylation factor-like protein 8B

1

0

High-throughput

0.279

Low

1451902

CKLF6
CKLF-like MARVEL transmembrane domain-containing protein 6

1

0

High-throughput

0.279

Low

1452225

SEC63
Translocation protein SEC63 homolog

1

0

High-throughput

0.279

Low

1452228

TMCO1
Calcium load-activated calcium channel

1

0

High-throughput

0.279

Low

106742

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

1447347

ANLN
Anillin

1

0

High-throughput

0.249

Low

592907

CBR1
Carbonyl reductase [NADPH] 1

1

0

High-throughput

0.232

Low

1120976

TRI29
Tripartite motif-containing protein 29

1

0

High-throughput

0.232

Low

1162159

MA2A1
Alpha-mannosidase 2

1

0

High-throughput

0.232

Low

1219554

ANR22
Ankyrin repeat domain-containing protein 22

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025