Protein: RT21
Small ribosomal subunit protein bS21m (28S ribosomal protein S21, mitochondrial) (MRP-S21) (S21mt)

Gene: RT21, MRPS21
Organism: Homo sapiens
Interactions: 106
UniProt ID: P82921

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0003735 - structural constituent of ribosome
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0005763 - mitochondrial small ribosomal subunit

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1012466

RT18C
Small ribosomal subunit protein bS18m

2

1

High-throughput

0.776

High

1012159

RT11
Small ribosomal subunit protein uS11m

2

0

High-throughput

0.770

High

1012465

RT02
Small ribosomal subunit protein uS2m

2

0

High-throughput

0.736

High

1012469

RT18B
Small ribosomal subunit protein mS40

2

0

High-throughput

0.736

High

1012418

TM10B
tRNA methyltransferase 10 homolog B

3

0

High-throughput

0.638

High

1012433

RT31
Small ribosomal subunit protein mS31

3

0

High-throughput

0.638

High

1012455

AKIP
Small ribosomal subunit protein mS38

3

0

High-throughput

0.638

High

1012432

RT27
Small ribosomal subunit protein mS27

3

0

High-throughput

0.634

High

1012297

RT15
Small ribosomal subunit protein uS15m

2

0

High-throughput

0.602

High

1012392

RT34
Small ribosomal subunit protein mS34

2

0

High-throughput

0.602

High

1012395

SRSF3
Serine/arginine-rich splicing factor 3

2

2

High-throughput

0.601

High

1012399

RL6
Large ribosomal subunit protein eL6

2

0

High-throughput

0.585

High

1012445

RT26
Small ribosomal subunit protein mS26

2

0

High-throughput

0.576

High

1012467

RT23
Small ribosomal subunit protein mS23

2

0

High-throughput

0.576

High

1012408

GRB7
Growth factor receptor-bound protein 7

2

0

High-throughput

0.547

High

481228

HMGB1
High mobility group protein B1

1

1

High-throughput

0.536

High

1012400

SRSF1
Serine/arginine-rich splicing factor 1

1

2

High-throughput

0.536

High

1012403

SRSF6
Serine/arginine-rich splicing factor 6

1

2

High-throughput

0.536

High

788630

SRP14
Signal recognition particle 14 kDa protein

1

0

High-throughput

0.513

High

842326

RL35
Large ribosomal subunit protein uL29

1

0

High-throughput

0.513

High

860155

RS9
Small ribosomal subunit protein uS4

1

0

High-throughput

0.513

High

994471

YBOX1
Y-box-binding protein 1

1

0

High-throughput

0.513

High

1009182

PRR3
Proline-rich protein 3

1

0

High-throughput

0.513

High

1011242

RT25
Small ribosomal subunit protein mS25

1

0

High-throughput

0.513

High

1012393

RT06
Small ribosomal subunit protein bS6m

1

0

High-throughput

0.513

High

1012394

RT09
Small ribosomal subunit protein uS9m

1

0

High-throughput

0.513

High

1012397

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

0

High-throughput

0.513

High

1012407

ICT1
Large ribosomal subunit protein mL62

1

0

High-throughput

0.513

High

1012412

RBMS2
RNA-binding motif, single-stranded-interacting protein 2

1

0

High-throughput

0.513

High

1012415

RM02
Large ribosomal subunit protein uL2m

1

0

High-throughput

0.513

High

1012420

COX15
Heme A synthase COX15

1

0

High-throughput

0.513

High

1012425

LDHD
Probable D-lactate dehydrogenase, mitochondrial

1

0

High-throughput

0.513

High

1012426

FABD
Malonyl-CoA-acyl carrier protein transacylase, mitochondrial

1

0

High-throughput

0.513

High

1012441

RT24
Small ribosomal subunit protein uS3m

1

0

High-throughput

0.513

High

1012444

RBM42
RNA-binding protein 42

1

0

High-throughput

0.513

High

1012457

TAP26
Thyroid transcription factor 1-associated protein 26

1

0

High-throughput

0.513

High

1012460

ABT1
Activator of basal transcription 1

1

0

High-throughput

0.513

High

1012464

RT17
Small ribosomal subunit protein uS17m

1

0

High-throughput

0.513

High

1012447

UBP44
Ubiquitin carboxyl-terminal hydrolase 44

1

1

High-throughput

0.489

High

275966

DUS11
RNA/RNP complex-1-interacting phosphatase

1

1

High-throughput

0.479

High

1012396

TFAM
Transcription factor A, mitochondrial

1

1

High-throughput

0.479

High

1012410

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

1

High-throughput

0.479

High

1012422

FAKD5
FAST kinase domain-containing protein 5, mitochondrial

1

1

High-throughput

0.479

High

1012436

FAKD4
FAST kinase domain-containing protein 4

1

1

High-throughput

0.479

High

1012442

EFGM
Elongation factor G, mitochondrial

1

1

High-throughput

0.479

High

66179

MET15
12S rRNA N(4)-cytidine methyltransferase METTL15

1

0

High-throughput

0.458

High

241389

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

350842

TRUB2
Pseudouridylate synthase TRUB2, mitochondrial

1

0

High-throughput

0.458

High

472636

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

0

High-throughput

0.458

High

532520

CH60
60 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.458

High

693687

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.458

High

828744

MDHM
Malate dehydrogenase, mitochondrial

1

0

High-throughput

0.458

High

841689

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

0

High-throughput

0.458

High

856240

IF2M
Translation initiation factor IF-2, mitochondrial

1

0

High-throughput

0.458

High

1012398

KIF23
Kinesin-like protein KIF23

1

0

High-throughput

0.458

High

1012401

GRSF1
G-rich sequence factor 1

1

0

High-throughput

0.458

High

1012404

SQSTM
Sequestosome-1

1

0

High-throughput

0.458

High

1012405

TRA2A
Transformer-2 protein homolog alpha

1

0

High-throughput

0.458

High

1012413

LARP7
La-related protein 7

1

0

High-throughput

0.458

High

1012417

MRM1
rRNA methyltransferase 1, mitochondrial

1

0

High-throughput

0.458

High

1012421

MEPCE
7SK snRNA methylphosphate capping enzyme

1

0

High-throughput

0.458

High

1012427

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.458

High

1012437

CHCH1
Small ribosomal subunit protein mS37

1

0

High-throughput

0.458

High

1012440

MTEF3
Transcription termination factor 3, mitochondrial

1

0

High-throughput

0.458

High

1012446

SLIRP
SRA stem-loop-interacting RNA-binding protein, mitochondrial

1

0

High-throughput

0.458

High

1012448

IF3M
Translation initiation factor IF-3, mitochondrial

1

0

High-throughput

0.458

High

1012449

MTRFR
Mitochondrial translation release factor in rescue

1

0

High-throughput

0.458

High

1012450

MET17
Ribosome assembly protein METTL17, mitochondrial

1

0

High-throughput

0.458

High

1012453

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

0

High-throughput

0.458

High

254353

CC14B
Dual specificity protein phosphatase CDC14B

1

1

High-throughput

0.437

High

371750

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.437

High

406057

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.437

High

1012416

Q6ICH2
single-stranded DNA cytosine deaminase

1

1

High-throughput

0.437

High

653249

HEMH
Ferrochelatase, mitochondrial

1

0

High-throughput

0.426

High

1012414

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

1012431

NOA1
Nitric oxide-associated protein 1

1

0

High-throughput

0.426

High

1012434

ESR2
Estrogen receptor beta

1

0

High-throughput

0.426

High

1012454

ATD3A
ATPase family AAA domain-containing protein 3A

1

0

High-throughput

0.426

High

1012456

F120A
Constitutive coactivator of PPAR-gamma-like protein 1

1

0

High-throughput

0.426

High

73389

B2CML4
single-stranded DNA cytosine deaminase

1

1

High-throughput

0.407

High

1012428

ZC3H3
Zinc finger CCCH domain-containing protein 3

2

0

High-throughput

0.318

High

830556

CCNF
Cyclin-F

2

0

High-throughput

0.305

High

1012406

CUL3
Cullin-3

1

0

High-throughput

0.279

Low

1012409

ZN460
Zinc finger protein 460

1

0

High-throughput

0.279

Low

1012419

H1FNT
Testis-specific H1 histone

1

0

High-throughput

0.279

Low

1012423

ZN467
Zinc finger protein 467

1

0

High-throughput

0.279

Low

1012424

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

0

High-throughput

0.279

Low

1012451

UBP42
Ubiquitin carboxyl-terminal hydrolase 42

1

0

High-throughput

0.279

Low

1012452

TF7L2
Transcription factor 7-like 2

1

0

High-throughput

0.279

Low

1012461

PADI4
Protein-arginine deiminase type-4

1

0

High-throughput

0.279

Low

1012463

MAST1
Microtubule-associated serine/threonine-protein kinase 1

1

0

High-throughput

0.279

Low

1012459

KLF15
Krueppel-like factor 15

1

0

High-throughput

0.261

Low

272073

OBSL1
Obscurin-like protein 1

1

0

High-throughput

0.249

Low

315455

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.249

Low

324783

HEXI1
Protein HEXIM1

1

0

High-throughput

0.249

Low

1012402

AAPK1
5'-AMP-activated protein kinase catalytic subunit alpha-1

1

0

High-throughput

0.249

Low

1012411

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.249

Low

1012430

FBXL6
F-box/LRR-repeat protein 6

1

0

High-throughput

0.249

Low

1012435

KAT6A
Histone acetyltransferase KAT6A

1

0

High-throughput

0.249

Low

1012438

CHM4C
Charged multivesicular body protein 4c

1

0

High-throughput

0.249

Low

1012439

GCP3
Gamma-tubulin complex component 3

1

0

High-throughput

0.249

Low

1012443

RING2
E3 ubiquitin-protein ligase RING2

1

0

High-throughput

0.249

Low

1012458

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.249

Low

1012462

FZR1
Fizzy-related protein homolog

1

0

High-throughput

0.249

Low

1012468

MAFB
Transcription factor MafB

1

0

High-throughput

0.249

Low

1012429

SLX4
Structure-specific endonuclease subunit SLX4

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025