Protein: PDC6I
Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (ALG-2-interacting protein X) (Hp95)

Gene: PDC6I, PDCD6IP
Organism: Homo sapiens
Interactions: 204
UniProt ID: Q8WUM4

Gene Ontology (top 5):
GO:0000281 - mitotic cytokinesis
GO:0000915 - actomyosin contractile ring assembly
GO:0001772 - immunological synapse
GO:0005768 - endosome
GO:0005813 - centrosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1260366

PDC6I
Programmed cell death 6-interacting protein

5

16

Small-scale

0.905

High

1120269

CEP55
Centrosomal protein of 55 kDa

10

5

Small-scale

0.761

High

1260384

TS101
Tumor susceptibility gene 101 protein

12

6

Small-scale

0.758

High

1260401

CHM4B
Charged multivesicular body protein 4b

11

19

Small-scale

0.758

High

259760

PDCD6
Programmed cell death protein 6

8

13

Small-scale

0.757

High

1260400

PTN23
Tyrosine-protein phosphatase non-receptor type 23

2

7

Small-scale

0.754

High

1260375

SH3K1
SH3 domain-containing kinase-binding protein 1

8

20

Small-scale

0.752

High

1260391

CHM4A
Charged multivesicular body protein 4a

6

19

Small-scale

0.733

High

338749

EGFR
Epidermal growth factor receptor

6

12

Small-scale

0.729

High

1260405

ALG2
Alpha-1,3/1,6-mannosyltransferase ALG2

5

1

Small-scale

0.712

High

476105

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

4

17

Small-scale

0.686

High

523081

SRC
Proto-oncogene tyrosine-protein kinase Src

3

16

Small-scale

0.684

High

1260385

SH3G1
Endophilin-A2

4

20

Small-scale

0.674

High

1260376

CHM4C
Charged multivesicular body protein 4c

3

19

Small-scale

0.658

High

1260386

SH3G2
Endophilin-A1

3

20

Small-scale

0.658

High

1260427

CD2AP
CD2-associated protein

3

20

Small-scale

0.647

High

1260392

ACE2
Angiotensin-converting enzyme 2

3

4

Small-scale

0.640

High

442861

HCK
Tyrosine-protein kinase HCK

2

16

Small-scale

0.636

High

850686

KS6A3
Ribosomal protein S6 kinase alpha-3

2

12

High-throughput

0.628

High

924726

GRB2
Growth factor receptor-bound protein 2

2

20

High-throughput

0.613

High

1260428

SAR1B
Small COPII coat GTPase SAR1B

2

3

High-throughput

0.611

High

626842

PAR1
Proteinase-activated receptor 1

3

2

Small-scale

0.606

High

1260420

TTF2
Transcription termination factor 2

2

15

Small-scale

0.600

High

125598

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

2

10

Small-scale

0.595

High

412278

FYN
Tyrosine-protein kinase Fyn

1

16

Small-scale

0.594

High

1260378

SGSM3
Small G protein signaling modulator 3

2

0

Small-scale

0.593

High

1245102

TNIP2
TNFAIP3-interacting protein 2

2

4

High-throughput

0.586

High

228172

PRKN
E3 ubiquitin-protein ligase parkin

2

20

High-throughput

0.584

High

1052830

FAK2
Protein-tyrosine kinase 2-beta

2

18

Small-scale

0.584

High

1191850

SH3R1
E3 ubiquitin-protein ligase SH3RF1

1

20

Small-scale

0.578

High

132966

SDCB1
Syntenin-1

1

5

Small-scale

0.573

High

572415

LEG3
Galectin-3

1

8

Small-scale

0.573

High

581803

VCAM1
Vascular cell adhesion protein 1

2

6

High-throughput

0.571

High

1080157

EZH2
Histone-lysine N-methyltransferase EZH2

2

6

High-throughput

0.549

High

1049283

KEAP1
Kelch-like ECH-associated protein 1

1

4

High-throughput

0.541

High

336558

SODC
Superoxide dismutase [Cu-Zn]

1

2

High-throughput

0.536

High

437555

CEL2A
Chymotrypsin-like elastase family member 2A

1

5

High-throughput

0.536

High

647636

MK03
Mitogen-activated protein kinase 3

1

7

High-throughput

0.536

High

659009

MK01
Mitogen-activated protein kinase 1

1

7

High-throughput

0.536

High

725842

SOAT1
Sterol O-acyltransferase 1

1

2

High-throughput

0.536

High

739206

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

3

High-throughput

0.536

High

801271

KI67
Proliferation marker protein Ki-67

1

8

High-throughput

0.536

High

904912

1433G
14-3-3 protein gamma

1

20

High-throughput

0.536

High

982323

1433F
14-3-3 protein eta

1

20

High-throughput

0.536

High

1042141

CUL3
Cullin-3

1

11

High-throughput

0.536

High

1071665

KS6A2
Ribosomal protein S6 kinase alpha-2

1

12

High-throughput

0.536

High

1204058

CARM1
Histone-arginine methyltransferase CARM1

1

8

High-throughput

0.536

High

1230150

CNTRB
Centrobin

1

16

High-throughput

0.536

High

1233123

RYBP
RING1 and YY1-binding protein

1

1

High-throughput

0.536

High

1256648

GEMI5
Gem-associated protein 5

1

7

High-throughput

0.536

High

1260369

TFG
Protein TFG

1

8

High-throughput

0.536

High

1260383

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

1

2

High-throughput

0.536

High

1260394

UBA5
Ubiquitin-like modifier-activating enzyme 5

1

2

High-throughput

0.536

High

1260402

MLP3A
Microtubule-associated proteins 1A/1B light chain 3A

1

6

High-throughput

0.536

High

1260410

ARL8B
ADP-ribosylation factor-like protein 8B

1

1

High-throughput

0.536

High

347428

MYC
Myc proto-oncogene protein

2

19

High-throughput

0.533

High

1234594

ARRD1
Arrestin domain-containing protein 1

1

7

Small-scale

0.527

High

723743

DRD3
D(3) dopamine receptor

1

3

Small-scale

0.523

High

433429

YES
Tyrosine-protein kinase Yes

1

17

Small-scale

0.515

High

1260429

STK24
Serine/threonine-protein kinase 24

1

20

High-throughput

0.515

High

168567

SCAM2
Secretory carrier-associated membrane protein 2

1

0

High-throughput

0.513

High

1260377

VMP1
Vacuole membrane protein 1

1

0

High-throughput

0.513

High

1260425

GOT1B
Vesicle transport protein GOT1B

1

0

High-throughput

0.513

High

1085449

MK06
Mitogen-activated protein kinase 6

1

17

High-throughput

0.508

High

1260424

RNF11
RING finger protein 11

1

4

High-throughput

0.508

High

273913

NU155
Nuclear pore complex protein Nup155

1

1

High-throughput

0.501

High

306249

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

6

High-throughput

0.501

High

891241

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

6

High-throughput

0.501

High

1166633

LRRN1
Leucine-rich repeat neuronal protein 1

1

5

High-throughput

0.501

High

1260380

NED4L
E3 ubiquitin-protein ligase NEDD4-like

1

10

Small-scale

0.501

High

1260387

NEUL2
Neuralized-like protein 2

1

2

Small-scale

0.501

High

1260389

MLP3C
Microtubule-associated proteins 1A/1B light chain 3C

1

6

High-throughput

0.501

High

1260396

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

6

High-throughput

0.501

High

1260399

SDCB2
Syntenin-2

1

6

High-throughput

0.501

High

625741

CXCR1
C-X-C chemokine receptor type 1

1

3

High-throughput

0.494

High

1260422

GSTK1
Glutathione S-transferase kappa 1

1

0

High-throughput

0.493

High

440637

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

3

High-throughput

0.489

High

1039718

SNW1
SNW domain-containing protein 1

1

2

High-throughput

0.489

High

1260370

SYN2
Synapsin-2

1

4

High-throughput

0.489

High

1260382

RING2
E3 ubiquitin-protein ligase RING2

1

17

High-throughput

0.489

High

1260390

TX101
Testis-expressed protein 101

1

2

High-throughput

0.489

High

1077916

TAB1
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1

1

0

High-throughput

0.486

High

600732

DRD1
D(1A) dopamine receptor

1

3

Small-scale

0.481

High

60618

VP37C
Vacuolar protein sorting-associated protein 37C

1

11

Small-scale

0.481

High

260147

VPS4B
Vacuolar protein sorting-associated protein 4B

1

9

Small-scale

0.481

High

1078881

ITSN1
Intersectin-1

1

9

High-throughput

0.481

High

1260374

ARRD3
Arrestin domain-containing protein 3

1

7

Small-scale

0.481

High

1260413

ITSN2
Intersectin-2

1

9

High-throughput

0.481

High

119456

LEG9
Galectin-9

1

7

High-throughput

0.479

High

155412

NRP1
Neuropilin-1

1

9

High-throughput

0.479

High

177953

TMPS2
Transmembrane protease serine 2

1

4

High-throughput

0.479

High

322920

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

10

High-throughput

0.479

High

324526

BAG3
BAG family molecular chaperone regulator 3

1

1

High-throughput

0.479

High

354517

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

2

High-throughput

0.479

High

377532

GCR
Glucocorticoid receptor

1

20

High-throughput

0.479

High

385230

NTRK1
High affinity nerve growth factor receptor

1

14

High-throughput

0.479

High

428332

TBB5
Tubulin beta chain

1

2

Small-scale

0.479

High

452462

PGFRB
Platelet-derived growth factor receptor beta

1

5

Small-scale

0.479

High

455693

PARP1
Poly [ADP-ribose] polymerase 1

1

7

High-throughput

0.479

High

504466

HSP7C
Heat shock cognate 71 kDa protein

1

2

High-throughput

0.479

High

526005

IFM1
Interferon-induced transmembrane protein 1

1

5

High-throughput

0.479

High

530704

ITA4
Integrin alpha-4

1

7

High-throughput

0.479

High

535492

GFAP
Glial fibrillary acidic protein

1

6

Small-scale

0.479

High

585667

TFE3
Transcription factor E3

1

10

High-throughput

0.479

High

591030

BTF3
Transcription factor BTF3

1

5

High-throughput

0.479

High

613267

ITA6
Integrin alpha-6

1

7

High-throughput

0.479

High

614082

TBG1
Tubulin gamma-1 chain

1

7

Small-scale

0.479

High

617613

CRCM
Colorectal mutant cancer protein

1

13

High-throughput

0.479

High

648839

DPP4
Dipeptidyl peptidase 4

1

3

High-throughput

0.479

High

666627

LTK
Leukocyte tyrosine kinase receptor

1

13

High-throughput

0.479

High

684918

STIP1
Stress-induced-phosphoprotein 1

1

4

High-throughput

0.479

High

717232

CTNB1
Catenin beta-1

1

8

High-throughput

0.479

High

719560

MERL
Merlin

1

9

High-throughput

0.479

High

726328

BASI
Basigin

1

3

High-throughput

0.479

High

779802

CCNF
Cyclin-F

1

9

High-throughput

0.479

High

799901

ABCG1
ATP-binding cassette sub-family G member 1

1

1

Small-scale

0.479

High

808202

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

10

Small-scale

0.479

High

822579

MASP1
Mannan-binding lectin serine protease 1

1

3

Small-scale

0.479

High

827984

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

3

High-throughput

0.479

High

829037

UBE2A
Ubiquitin-conjugating enzyme E2 A

1

1

High-throughput

0.479

High

835903

GSK3B
Glycogen synthase kinase-3 beta

1

17

High-throughput

0.479

High

875151

TERA
Transitional endoplasmic reticulum ATPase

1

3

High-throughput

0.479

High

908874

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

6

High-throughput

0.479

High

932280

ACTC
Actin, alpha cardiac muscle 1

1

12

Small-scale

0.479

High

961210

HSF1
Heat shock factor protein 1

1

5

High-throughput

0.479

High

983641

FAK1
Focal adhesion kinase 1

1

20

Small-scale

0.479

High

1014057

AP1B1
AP-1 complex subunit beta-1

1

11

High-throughput

0.479

High

1030380

G3BP1
Ras GTPase-activating protein-binding protein 1

1

4

High-throughput

0.479

High

1035924

BIRC3
Baculoviral IAP repeat-containing protein 3

1

11

High-throughput

0.479

High

1047781

CKAP5
Cytoskeleton-associated protein 5

1

12

High-throughput

0.479

High

1050242

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

13

High-throughput

0.479

High

1064522

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

4

High-throughput

0.479

High

1066448

KIF14
Kinesin-like protein KIF14

1

10

High-throughput

0.479

High

1068529

PLCB4
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4

1

2

High-throughput

0.479

High

1085852

IF16
Gamma-interferon-inducible protein 16

1

3

High-throughput

0.479

High

1173988

UBP53
Inactive ubiquitin carboxyl-terminal hydrolase 53

1

9

Small-scale

0.479

High

1175057

TBA1A
Tubulin alpha-1A chain

1

3

Small-scale

0.479

High

1189511

ZFY16
Zinc finger FYVE domain-containing protein 16

1

18

Small-scale

0.479

High

1222482

SLX4
Structure-specific endonuclease subunit SLX4

1

14

High-throughput

0.479

High

1231283

RHG24
Rho GTPase-activating protein 24

1

5

High-throughput

0.479

High

1232179

ASCC3
Activating signal cointegrator 1 complex subunit 3

1

9

High-throughput

0.479

High

1237426

CGAS
Cyclic GMP-AMP synthase

1

1

High-throughput

0.479

High

1244631

NUP35
Nucleoporin NUP35

1

1

High-throughput

0.479

High

1260368

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

6

High-throughput

0.479

High

1260371

STAM1
Signal transducing adapter molecule 1

1

20

Small-scale

0.479

High

1260373

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

15

Small-scale

0.479

High

1260379

ITCH
E3 ubiquitin-protein ligase Itchy homolog

1

10

High-throughput

0.479

High

1260381

RUFY1
RUN and FYVE domain-containing protein 1

1

15

High-throughput

0.479

High

1260388

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

10

High-throughput

0.479

High

1260393

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

6

High-throughput

0.479

High

1260395

TOLIP
Toll-interacting protein

1

1

High-throughput

0.479

High

1260397

CCDC8
Coiled-coil domain-containing protein 8

1

2

High-throughput

0.479

High

1260398

ABCG4
ATP-binding cassette sub-family G member 4

1

1

Small-scale

0.479

High

1260406

ECT2
Protein ECT2

1

9

High-throughput

0.479

High

1260407

RHOF
Rho-related GTP-binding protein RhoF

1

19

High-throughput

0.479

High

1260408

ANLN
Anillin

1

6

High-throughput

0.479

High

1260412

WWOX
WW domain-containing oxidoreductase

1

6

High-throughput

0.479

High

1260415

ZRAN1
Ubiquitin thioesterase ZRANB1

1

10

High-throughput

0.479

High

1260416

TES
Testin

1

9

High-throughput

0.479

High

1260417

UBQL2
Ubiquilin-2

1

5

High-throughput

0.479

High

1260418

DDX20
Probable ATP-dependent RNA helicase DDX20

1

13

High-throughput

0.479

High

1260419

CLC4E
C-type lectin domain family 4 member E

1

7

High-throughput

0.479

High

353011

IL1B
Interleukin-1 beta

1

0

Small-scale

0.458

High

400358

RLA1
Large ribosomal subunit protein P1

1

0

High-throughput

0.458

High

532583

TCTP
Translationally-controlled tumor protein

1

0

High-throughput

0.458

High

1047451

PEBB
Core-binding factor subunit beta

1

0

High-throughput

0.458

High

1260372

SC5A5
Sodium/iodide cotransporter

1

0

Small-scale

0.458

High

902684

SUMO2
Small ubiquitin-related modifier 2

1

4

High-throughput

0.457

High

245382

RAMP3
Receptor activity-modifying protein 3

1

1

High-throughput

0.457

High

529473

CFTR
Cystic fibrosis transmembrane conductance regulator

1

10

High-throughput

0.445

High

1047177

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

9

High-throughput

0.445

High

214328

SPOP
Speckle-type POZ protein

1

6

High-throughput

0.437

High

244695

BRD4
Bromodomain-containing protein 4

1

8

High-throughput

0.437

High

260587

TP4A3
Protein tyrosine phosphatase type IVA 3

1

8

High-throughput

0.437

High

328907

TOP3B
DNA topoisomerase 3-beta-1

1

1

High-throughput

0.437

High

329855

AGR2
Anterior gradient protein 2 homolog

1

5

High-throughput

0.437

High

524575

LYL1
Protein lyl-1

1

7

High-throughput

0.437

High

553278

RFA2
Replication protein A 32 kDa subunit

1

9

High-throughput

0.437

High

734711

TRI23
E3 ubiquitin-protein ligase TRIM23

1

2

High-throughput

0.437

High

749708

BRCA1
Breast cancer type 1 susceptibility protein

1

15

High-throughput

0.437

High

824219

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

14

High-throughput

0.437

High

903387

WDR5
WD repeat-containing protein 5

1

9

Small-scale

0.437

High

965771

IFM3
Interferon-induced transmembrane protein 3

1

5

High-throughput

0.437

High

1116766

DUS28
Dual specificity phosphatase 28

1

5

High-throughput

0.437

High

1116874

FBX43
F-box only protein 43

1

1

Small-scale

0.437

High

1165794

LMBRL
Protein LMBR1L

1

2

High-throughput

0.437

High

1170978

TRI67
Tripartite motif-containing protein 67

1

18

High-throughput

0.437

High

1188612

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

2

High-throughput

0.437

High

1260367

CLC4D
C-type lectin domain family 4 member D

1

6

High-throughput

0.437

High

1260403

SENP3
Sentrin-specific protease 3

1

1

Small-scale

0.437

High

1260404

PKHA4
Pleckstrin homology domain-containing family A member 4

1

18

High-throughput

0.437

High

1260409

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

11

High-throughput

0.437

High

1260411

PIHD1
PIH1 domain-containing protein 1

1

1

High-throughput

0.437

High

1260414

TR10D
Tumor necrosis factor receptor superfamily member 10D

1

7

High-throughput

0.437

High

1260421

TRI33
E3 ubiquitin-protein ligase TRIM33

1

17

High-throughput

0.437

High

1260423

AAR2
Protein AAR2 homolog

1

3

High-throughput

0.437

High

253490

PLXA2
Plexin-A2

1

3

Small-scale

0.417

High

240109

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

5

High-throughput

0.407

High

1043989

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

19

High-throughput

0.407

High

452837

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

0

High-throughput

0.279

Low

1063517

SUZ12
Polycomb protein SUZ12

1

0

High-throughput

0.279

Low

1260426

PHLA3
Pleckstrin homology-like domain family A member 3

1

0

High-throughput

0.269

Low

1062176

HAPR1
HUWE1-associated protein modifying stress responses 1

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024