Protein: PADI4
Protein-arginine deiminase type-4 (EC 3.5.3.15) (HL-60 PAD) (Peptidylarginine deiminase IV) (Protein-arginine deiminase type IV)

Gene: PADI4
Organism: Homo sapiens
Interactions: 34
UniProt ID: Q9UM07

Gene Ontology (top 5):
GO:0004668 - protein-arginine deiminase activity
GO:0005509 - calcium ion binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1461822

PADI3
Protein-arginine deiminase type-3

2

3

High-throughput

0.811

High

1461889

PADI4
Protein-arginine deiminase type-4

1

3

Small-scale

0.647

High

483465

ANXA4
Annexin A4

3

0

High-throughput

0.646

High

414841

P53
Cellular tumor antigen p53

2

1

Small-scale

0.624

High

1008001

PO6F2
POU domain, class 6, transcription factor 2

2

0

High-throughput

0.580

High

1402062

TRIB3
Tribbles homolog 3

2

0

High-throughput

0.580

High

1110188

HDAC1
Histone deacetylase 1

1

1

Small-scale

0.561

High

1368207

HDAC2
Histone deacetylase 2

1

1

Small-scale

0.561

High

447575

NPM
Nucleophosmin

1

0

Small-scale

0.554

High

1461890

ING4
Inhibitor of growth protein 4

1

0

Small-scale

0.537

High

1028448

MDM2
E3 ubiquitin-protein ligase Mdm2

1

0

Small-scale

0.527

High

1209792

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

Small-scale

0.513

High

899278

TCPQ
T-complex protein 1 subunit theta

1

0

High-throughput

0.513

High

1110321

KCC2B
Calcium/calmodulin-dependent protein kinase type II subunit beta

1

0

High-throughput

0.513

High

1226608

MAP1S
Microtubule-associated protein 1S

1

0

High-throughput

0.513

High

1394227

GMPPA
Mannose-1-phosphate guanylyltransferase regulatory subunit alpha

1

0

High-throughput

0.513

High

1430197

CSTFT
Cleavage stimulation factor subunit 2 tau variant

1

0

High-throughput

0.513

High

1452434

MTMR4
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR4

1

0

High-throughput

0.513

High

1461891

MOFA1
MORF4 family-associated protein 1

1

0

High-throughput

0.513

High

644236

RS4Y1
Small ribosomal subunit protein eS4, Y isoform 1

1

0

High-throughput

0.493

High

1233271

ELP2
Elongator complex protein 2

1

0

High-throughput

0.493

High

210799

KLK10
Kallikrein-10

1

1

High-throughput

0.489

High

423448

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

1258977

H32
Histone H3.2

1

0

Small-scale

0.480

High

1326144

RYBP
RING1 and YY1-binding protein

1

0

Small-scale

0.480

High

1349783

FBX25
F-box only protein 25

1

0

Small-scale

0.480

High

1439009

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

0

Small-scale

0.480

High

622486

ELK1
ETS domain-containing protein Elk-1

1

0

Small-scale

0.458

High

1461474

DNPEP
Aspartyl aminopeptidase

1

0

High-throughput

0.458

High

1011218

RT22
Small ribosomal subunit protein mS22

1

0

High-throughput

0.279

Low

1012461

RT21
Small ribosomal subunit protein bS21m

1

0

High-throughput

0.279

Low

1366467

RT31
Small ribosomal subunit protein mS31

1

0

High-throughput

0.279

Low

1460842

GBG8
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8

1

0

High-throughput

0.279

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025