Protein: AT131
Endoplasmic reticulum transmembrane helix translocase (EC 7.4.2.-) (Endoplasmic reticulum P5A-ATPase)

Gene: AT131, ATP13A1
Organism: Homo sapiens
Interactions: 165
UniProt ID: Q9HD20

Gene Ontology (top 5):
GO:0005524 - ATP binding
GO:0005789 - endoplasmic reticulum membrane
GO:0006874 - intracellular calcium ion homeostasis
GO:0015031 - protein transport
GO:0015410 - ABC-type manganese transporter activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

946066

DLK1
Protein delta homolog 1

3

4

High-throughput

0.667

High

1336579

SCN3B
Sodium channel regulatory subunit beta-3

3

6

High-throughput

0.665

High

163993

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

12

High-throughput

0.618

High

625779

CXCR2
C-X-C chemokine receptor type 2

2

20

High-throughput

0.606

High

874693

BI1
Bax inhibitor 1

2

1

High-throughput

0.606

High

1108638

SOAT
Sodium-dependent organic anion transporter

2

2

High-throughput

0.606

High

1139346

SYPL2
Synaptophysin-like protein 2

2

1

High-throughput

0.606

High

1203122

UN93A
Protein unc-93 homolog A

2

4

High-throughput

0.606

High

1224159

KMT2E
Inactive histone-lysine N-methyltransferase 2E

2

5

High-throughput

0.606

High

1298176

TLCD4
TLC domain-containing protein 4

2

1

High-throughput

0.606

High

1310010

ZNT2
Proton-coupled zinc antiporter SLC30A2

2

3

High-throughput

0.606

High

1326298

ELOV4
Very long chain fatty acid elongase 4

2

6

High-throughput

0.606

High

890440

SC61B
Protein transport protein Sec61 subunit beta

2

4

High-throughput

0.584

High

1068360

EBP
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase

2

0

High-throughput

0.580

High

1074894

PAQRB
Monocyte to macrophage differentiation factor

2

0

High-throughput

0.580

High

1114061

VMA21
Vacuolar ATPase assembly integral membrane protein VMA21

2

0

High-throughput

0.580

High

1131210

MF14B
Hippocampus abundant transcript-like protein 1

2

0

High-throughput

0.580

High

1160113

RNK
Ribonuclease kappa

2

0

High-throughput

0.580

High

1300151

TM237
Transmembrane protein 237

2

0

High-throughput

0.580

High

1336572

MANBL
Protein MANBAL

2

0

High-throughput

0.580

High

1199493

LRRT1
Leucine-rich repeat transmembrane neuronal protein 1

2

14

High-throughput

0.574

High

370487

ESR1
Estrogen receptor

2

9

High-throughput

0.571

High

925638

RAC1
Ras-related C3 botulinum toxin substrate 1

2

20

High-throughput

0.571

High

183299

FFAR2
Free fatty acid receptor 2

2

20

High-throughput

0.553

High

1037728

AQP6
Aquaporin-6

2

1

High-throughput

0.553

High

1186304

MOT13
Monocarboxylate transporter 13

2

6

High-throughput

0.553

High

1219487

ZNT8
Proton-coupled zinc antiporter SLC30A8

2

3

High-throughput

0.553

High

1336573

S35C2
Solute carrier family 35 member C2

2

1

High-throughput

0.553

High

793763

GLP1R
Glucagon-like peptide 1 receptor

1

10

Small-scale

0.552

High

674882

AGTR1
Type-1 angiotensin II receptor

1

20

High-throughput

0.541

High

123730

PGRC1
Membrane-associated progesterone receptor component 1

1

5

High-throughput

0.536

High

170959

PGRC2
Membrane-associated progesterone receptor component 2

1

5

High-throughput

0.536

High

213166

SNG1
Synaptogyrin-1

1

2

High-throughput

0.536

High

217360

TYOBP
TYRO protein tyrosine kinase-binding protein

1

3

High-throughput

0.536

High

351196

TGFA
Protransforming growth factor alpha [Cleaved into: Transforming growth factor alpha

1

1

High-throughput

0.536

High

626800

PTAFR
Platelet-activating factor receptor

1

20

High-throughput

0.536

High

639649

TNR5
Tumor necrosis factor receptor superfamily member 5

1

14

High-throughput

0.536

High

654804

CALX
Calnexin

1

6

High-throughput

0.536

High

673988

HLAF
HLA class I histocompatibility antigen, alpha chain F

1

5

High-throughput

0.536

High

702801

CADH5
Cadherin-5

1

5

High-throughput

0.536

High

823102

AGRE5
Adhesion G protein-coupled receptor E5

1

5

High-throughput

0.536

High

1027801

PSMD2
26S proteasome non-ATPase regulatory subunit 2

1

2

High-throughput

0.536

High

1053823

PIGH
Phosphatidylinositol N-acetylglucosaminyltransferase subunit H

1

3

High-throughput

0.536

High

1109951

SHSL1
Protein shisa-like-1

1

1

High-throughput

0.536

High

1156896

NIPA3
Magnesium transporter NIPA3

1

2

High-throughput

0.536

High

1202854

TPRA1
Transmembrane protein adipocyte-associated 1

1

2

High-throughput

0.536

High

1232079

LRC25
Leucine-rich repeat-containing protein 25

1

1

High-throughput

0.536

High

1237736

F241A
Uncharacterized protein FAM241A

1

1

High-throughput

0.536

High

1283291

CCD47
PAT complex subunit CCDC47

1

3

High-throughput

0.536

High

1305747

KI2L4
Killer cell immunoglobulin-like receptor 2DL4

1

3

High-throughput

0.536

High

1329169

CXL16
C-X-C motif chemokine 16

1

2

High-throughput

0.536

High

1336578

EVA1B
Protein eva-1 homolog B

1

1

High-throughput

0.536

High

1336585

VSIG4
V-set and immunoglobulin domain-containing protein 4

1

5

High-throughput

0.536

High

1336588

ENTP2
Ectonucleoside triphosphate diphosphohydrolase 2

1

7

High-throughput

0.536

High

964438

RUNX1
Runt-related transcription factor 1

1

0

High-throughput

0.518

High

1261146

CC107
Coiled-coil domain-containing protein 107

1

0

High-throughput

0.513

High

1336583

CC018
Uncharacterized protein C3orf18

1

0

High-throughput

0.513

High

66503

CLM7
CMRF35-like molecule 7

1

6

High-throughput

0.489

High

68248

HECA2
HEPACAM family member 2

1

2

High-throughput

0.489

High

206011

TGON2
Trans-Golgi network integral membrane protein 2

1

6

High-throughput

0.489

High

238925

TPST2
Protein-tyrosine sulfotransferase 2

1

4

High-throughput

0.489

High

326227

TSN15
Tetraspanin-15

1

16

High-throughput

0.489

High

577447

GBRG2
Gamma-aminobutyric acid receptor subunit gamma-2

1

3

High-throughput

0.489

High

645827

CD27
CD27 antigen

1

13

High-throughput

0.489

High

655202

IL1R2
Interleukin-1 receptor type 2

1

1

High-throughput

0.489

High

849710

CCR6
C-C chemokine receptor type 6

1

20

High-throughput

0.489

High

875509

IOD3
Thyroxine 5-deiodinase

1

1

High-throughput

0.489

High

964138

CD83
CD83 antigen

1

1

High-throughput

0.489

High

989756

TNR9
Tumor necrosis factor receptor superfamily member 9

1

13

High-throughput

0.489

High

1078230

CD226
CD226 antigen

1

7

High-throughput

0.489

High

1125131

TTMP
TPA-induced transmembrane protein

1

3

High-throughput

0.489

High

1134301

LRAD1
Low-density lipoprotein receptor class A domain-containing protein 1

1

2

High-throughput

0.489

High

1166230

VSTM1
V-set and transmembrane domain-containing protein 1

1

3

High-throughput

0.489

High

1182911

BT2A1
Butyrophilin subfamily 2 member A1

1

7

High-throughput

0.489

High

1232356

TM130
Transmembrane protein 130

1

1

High-throughput

0.489

High

1252602

S7A14
Solute carrier family 7 member 14

1

2

High-throughput

0.489

High

1255462

GPBAR
G-protein coupled bile acid receptor 1

1

1

High-throughput

0.489

High

1291438

ASIC4
Acid-sensing ion channel 4

1

1

High-throughput

0.489

High

1294900

TXD15
Thioredoxin domain-containing protein 15

1

2

High-throughput

0.489

High

1299249

OPALI
Opalin

1

3

High-throughput

0.489

High

1318472

CD244
Natural killer cell receptor 2B4

1

9

High-throughput

0.489

High

1328928

TSN10
Tetraspanin-10

1

16

High-throughput

0.489

High

1333282

PACC1
Proton-activated chloride channel

1

2

High-throughput

0.489

High

1335590

LPAR2
Lysophosphatidic acid receptor 2

1

20

High-throughput

0.489

High

1336587

PCDGL
Protocadherin gamma-C4

1

13

High-throughput

0.489

High

335550

NB5R3
NADH-cytochrome b5 reductase 3

1

7

High-throughput

0.481

High

1336586

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

1

3

High-throughput

0.481

High

242897

TRI13
E3 ubiquitin-protein ligase TRIM13

1

3

High-throughput

0.479

High

273999

NU155
Nuclear pore complex protein Nup155

1

3

High-throughput

0.479

High

374915

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

3

High-throughput

0.479

High

385556

NTRK1
High affinity nerve growth factor receptor

1

7

High-throughput

0.479

High

390547

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

3

High-throughput

0.479

High

391189

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

3

High-throughput

0.479

High

455897

PARP1
Poly [ADP-ribose] polymerase 1

1

2

High-throughput

0.479

High

507250

LAMP1
Lysosome-associated membrane glycoprotein 1

1

10

High-throughput

0.479

High

527809

LAMP2
Lysosome-associated membrane glycoprotein 2

1

10

High-throughput

0.479

High

640632

DDX6
Probable ATP-dependent RNA helicase DDX6

1

3

High-throughput

0.479

High

652317

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.479

High

750481

COIL
Coilin

1

2

High-throughput

0.479

High

795294

SSRA
Translocon-associated protein subunit alpha

1

2

High-throughput

0.479

High

839153

EMD
Emerin

1

3

High-throughput

0.479

High

847667

BAP31
B-cell receptor-associated protein 31

1

3

High-throughput

0.479

High

900933

RHOA
Transforming protein RhoA

1

20

High-throughput

0.479

High

913128

ARF6
ADP-ribosylation factor 6

1

5

High-throughput

0.479

High

1036104

BIRC3
Baculoviral IAP repeat-containing protein 3

1

2

High-throughput

0.479

High

1062675

EMC2
ER membrane protein complex subunit 2

1

3

High-throughput

0.479

High

1087617

CAH9
Carbonic anhydrase 9

1

3

High-throughput

0.479

High

1132453

MARH8
E3 ubiquitin-protein ligase MARCHF8

1

4

High-throughput

0.479

High

1165970

LMBRL
Protein LMBR1L

1

3

High-throughput

0.479

High

1204842

GOLI
E3 ubiquitin-protein ligase RNF130

1

8

High-throughput

0.479

High

1237000

EMC1
ER membrane protein complex subunit 1

1

3

High-throughput

0.479

High

1240786

RN149
E3 ubiquitin-protein ligase RNF149

1

8

High-throughput

0.479

High

1255696

RBCC1
RB1-inducible coiled-coil protein 1

1

6

High-throughput

0.479

High

1270705

REQU
Zinc finger protein ubi-d4

1

4

High-throughput

0.479

High

1282648

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

3

High-throughput

0.479

High

1300788

PANX1
Pannexin-1

1

1

High-throughput

0.479

High

1303582

SEC62
Translocation protein SEC62

1

5

High-throughput

0.479

High

1313063

DERL1
Derlin-1

1

2

High-throughput

0.479

High

1328862

DJC25
DnaJ homolog subfamily C member 25

1

4

High-throughput

0.479

High

1329288

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

6

High-throughput

0.479

High

1333577

TMT1A
Thiol S-methyltransferase TMT1A

1

2

High-throughput

0.479

High

1336574

PXMP2
Peroxisomal membrane protein 2

1

2

High-throughput

0.479

High

1336580

ELOV5
Very long chain fatty acid elongase 5

1

6

High-throughput

0.479

High

1336581

ZRAN1
Ubiquitin thioesterase ZRANB1

1

4

High-throughput

0.479

High

1336582

SEC63
Translocation protein SEC63 homolog

1

7

High-throughput

0.479

High

182037

GPR42
G-protein coupled receptor 42

1

20

High-throughput

0.470

High

514727

CP2C9
Cytochrome P450 2C9

1

0

High-throughput

0.458

High

1130617

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

5

High-throughput

0.445

High

1241629

MOT11
Monocarboxylate transporter 11

1

6

High-throughput

0.445

High

1016149

ARHG5
Rho guanine nucleotide exchange factor 5

1

4

High-throughput

0.439

High

1060725

NTCP
Hepatic sodium/bile acid cotransporter

1

2

High-throughput

0.439

High

360443

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

1

High-throughput

0.437

High

398098

ISG15
Ubiquitin-like protein ISG15

1

7

High-throughput

0.437

High

553779

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.437

High

670228

MARCS
Myristoylated alanine-rich C-kinase substrate

1

2

High-throughput

0.437

High

721509

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.437

High

780142

CCNF
Cyclin-F

1

2

High-throughput

0.437

High

844752

RAB5C
Ras-related protein Rab-5C

1

12

High-throughput

0.437

High

959694

VIGLN
Vigilin

1

1

High-throughput

0.437

High

961833

REEP5
Receptor expression-enhancing protein 5

1

2

High-throughput

0.437

High

1156721

TECT3
Tectonic-3

1

4

High-throughput

0.437

High

1171811

TRI67
Tripartite motif-containing protein 67

1

7

High-throughput

0.437

High

1230385

CXD3
Gap junction delta-3 protein

1

8

High-throughput

0.437

High

1240311

DHB11
Estradiol 17-beta-dehydrogenase 11

1

4

High-throughput

0.437

High

1244710

NUP35
Nucleoporin NUP35

1

1

High-throughput

0.437

High

1269680

ESR2
Estrogen receptor beta

1

9

High-throughput

0.437

High

1292872

TECT2
Tectonic-2

1

4

High-throughput

0.437

High

1331349

PKHA4
Pleckstrin homology domain-containing family A member 4

1

8

High-throughput

0.437

High

1336577

OTULL
Inactive ubiquitin thioesterase OTULINL

1

1

High-throughput

0.437

High

1336584

LAMP3
Lysosome-associated membrane glycoprotein 3

1

10

High-throughput

0.437

High

1103089

ATG2A
Autophagy-related protein 2 homolog A

1

0

Small-scale

0.426

High

1295200

VCIP1
Deubiquitinating protein VCPIP1

2

0

High-throughput

0.328

High

1319184

ZY11B
Protein zyg-11 homolog B

2

0

High-throughput

0.328

High

1128722

F209A
Protein FAM209A

2

0

High-throughput

0.316

High

1231986

CBARP
Voltage-dependent calcium channel beta subunit-associated regulatory protein

2

0

High-throughput

0.316

High

1268453

APBP2
Amyloid protein-binding protein 2

2

0

High-throughput

0.316

High

1336576

TM14B
Transmembrane protein 14B

2

0

High-throughput

0.316

High

782179

BUD31
Protein BUD31 homolog

1

0

High-throughput

0.282

High

599769

SCF
Kit ligand

1

0

High-throughput

0.279

Low

1173419

RHEX
Regulator of hemoglobinization and erythroid cell expansion protein

1

0

High-throughput

0.279

Low

1262582

KCNE4
Potassium voltage-gated channel subfamily E member 4

1

0

High-throughput

0.279

Low

1332858

SPRNG
SREBP regulating gene protein

1

0

High-throughput

0.279

Low

1336575

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.279

Low

1031796

BIK
Bcl-2-interacting killer

1

0

High-throughput

0.251

Low

1251034

SNIP1
Smad nuclear-interacting protein 1

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024