Protein: KDM8
Bifunctional peptidase and arginyl-hydroxylase JMJD5 (EC 1.14.11.73) (EC 3.4.-.-) (JmjC domain-containing protein 5) (Jumonji C domain-containing protein 5) (L-arginine (3R)-hydroxylase KDM8)

Gene: KDM8
Organism: Homo sapiens
Interactions: 30
UniProt ID: Q8N371

Gene Ontology (top 5):
GO:0000086 - G2/M transition of mitotic cell cycle
GO:0001701 - in utero embryonic development
GO:0002039 - p53 binding
GO:0003682 - chromatin binding
GO:0004175 - endopeptidase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

64887

RCCD1
RCC1 domain-containing protein 1

4

2

High-throughput

0.699

High

1324816

ISY1
Pre-mRNA-splicing factor ISY1 homolog

3

0

High-throughput

0.636

High

569261

YJU2B
Probable splicing factor YJU2B

3

2

High-throughput

0.609

High

1308414

UN5CL
UNC5C-like protein

2

0

High-throughput

0.602

High

1232454

Q6FHY5
MEOX2 protein

2

3

High-throughput

0.596

High

894007

MEOX2
Homeobox protein MOX-2

2

3

High-throughput

0.584

High

1324809

NUBPL
Iron-sulfur cluster transfer protein NUBPL

2

0

High-throughput

0.580

High

1324815

HTR5B
HEAT repeat-containing protein 5B

1

0

Small-scale

0.554

High

573168

KPYM
Pyruvate kinase PKM

1

0

Small-scale

0.537

High

426534

HMGN2
Non-histone chromosomal protein HMG-17

1

1

High-throughput

0.536

High

946833

H2B1D
Histone H2B type 1-D

1

8

High-throughput

0.536

High

65517

CAN8
Calpain-8

1

0

High-throughput

0.513

High

141781

MFNG
Beta-1,3-N-acetylglucosaminyltransferase manic fringe

1

0

High-throughput

0.513

High

424434

HMGN1
Non-histone chromosomal protein HMG-14

1

0

High-throughput

0.513

High

1324808

EIF1A
Probable RNA-binding protein EIF1AD

1

0

High-throughput

0.513

High

998538

H31
Histone H3.1

1

20

High-throughput

0.501

High

1324812

PCY2
Ethanolamine-phosphate cytidylyltransferase

1

1

High-throughput

0.494

High

1324813

CSTL1
Cystatin-like 1

1

1

High-throughput

0.489

High

1220642

RN123
E3 ubiquitin-protein ligase RNF123

1

10

High-throughput

0.479

High

1281559

SLN11
Schlafen family member 11

1

4

High-throughput

0.479

High

1324814

BACD3
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3

1

2

Small-scale

0.479

High

1324817

TRRAP
Transformation/transcription domain-associated protein

1

2

High-throughput

0.479

High

749231

CD70
CD70 antigen

2

0

High-throughput

0.328

High

1313651

IFT20
Intraflagellar transport protein 20 homolog

2

0

High-throughput

0.316

High

1324810

DDT4L
DNA damage-inducible transcript 4-like protein

2

0

High-throughput

0.316

High

253865

TPST2
Protein-tyrosine sulfotransferase 2

1

0

High-throughput

0.279

Low

322153

GLCE
D-glucuronyl C5-epimerase

1

0

High-throughput

0.279

Low

553432

FCERA
High affinity immunoglobulin epsilon receptor subunit alpha

1

0

High-throughput

0.279

Low

914299

EFNA4
Ephrin-A4

1

0

High-throughput

0.279

Low

1324811

COX42
Cytochrome c oxidase subunit 4 isoform 2, mitochondrial

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025