Protein: LRC41
Leucine-rich repeat-containing protein 41 (Protein Muf1)

Gene: LRC41, LRRC41
Organism: Homo sapiens
Interactions: 80
UniProt ID: Q15345

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0016020 - membrane
GO:0016567 - protein ubiquitination

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1146388

CUL5
Cullin-5

5

1

Small-scale

0.718

High

1146411

DRG1
Developmentally-regulated GTP-binding protein 1

5

0

High-throughput

0.684

High

1146406

RBX2
RING-box protein 2

3

1

Small-scale

0.650

High

873465

PP2BC
Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform

3

0

High-throughput

0.638

High

1146369

ELOB
Elongin-B

3

0

Small-scale

0.613

High

300359

KRT34
Keratin, type I cuticular Ha4

2

1

High-throughput

0.606

High

1145945

K1H1
Keratin, type I cuticular Ha1

2

1

High-throughput

0.606

High

622811

ERCC3
General transcription and DNA repair factor IIH helicase/translocase subunit XPB

2

0

High-throughput

0.602

High

1146380

UN5CL
UNC5C-like protein

2

0

High-throughput

0.602

High

1146381

EXOC8
Exocyst complex component 8

2

0

High-throughput

0.602

High

1113164

CUL3
Cullin-3

2

1

High-throughput

0.584

High

1146372

KRA62
Keratin-associated protein 6-2

2

0

High-throughput

0.580

High

1146375

FHL5
Four and a half LIM domains protein 5

2

0

High-throughput

0.580

High

1146400

KRA31
Keratin-associated protein 3-1

2

0

High-throughput

0.580

High

1146368

ELOC
Elongin-C

2

0

Small-scale

0.559

High

1146407

ZRAN1
Ubiquitin thioesterase ZRANB1

2

0

High-throughput

0.559

High

1106193

MYO9B
Unconventional myosin-IXb

1

0

High-throughput

0.518

High

1146389

RBPMS
RNA-binding protein with multiple splicing

1

0

High-throughput

0.518

High

349675

BPNT1
3'(2'),5'-bisphosphate nucleotidase 1

1

0

High-throughput

0.513

High

1146370

TEAD2
Transcriptional enhancer factor TEF-4

1

0

High-throughput

0.513

High

1146374

LRAD1
Low-density lipoprotein receptor class A domain-containing protein 1

1

0

High-throughput

0.513

High

1146383

NSE1
Non-structural maintenance of chromosomes element 1 homolog

1

0

High-throughput

0.513

High

1146390

EFMT3
EEF1A lysine methyltransferase 3

1

0

High-throughput

0.513

High

1146392

DCNL1
DCN1-like protein 1

1

0

High-throughput

0.513

High

1146398

DPYL5
Dihydropyrimidinase-related protein 5

1

0

High-throughput

0.513

High

1146408

NDOR1
NADPH-dependent diflavin oxidoreductase 1

1

0

High-throughput

0.513

High

1146412

MAST1
Microtubule-associated serine/threonine-protein kinase 1

1

0

High-throughput

0.513

High

1146413

SGT1
Protein SGT1 homolog

1

0

High-throughput

0.513

High

1146376

DDI2
Protein DDI1 homolog 2

1

0

High-throughput

0.493

High

1146373

SMUG1
Single-strand selective monofunctional uracil DNA glycosylase

1

0

High-throughput

0.493

High

508011

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

0

High-throughput

0.480

High

404069

GCR
Glucocorticoid receptor

1

1

High-throughput

0.479

High

883546

CENPA
Histone H3-like centromeric protein A

1

2

High-throughput

0.479

High

998344

H31
Histone H3.1

1

2

High-throughput

0.479

High

1016883

H33
Histone H3.3

1

2

High-throughput

0.479

High

1146382

RHG24
Rho GTPase-activating protein 24

1

1

High-throughput

0.479

High

1146387

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

1146397

BARD1
BRCA1-associated RING domain protein 1

1

2

High-throughput

0.479

High

1146402

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.479

High

174762

SPTN2
Spectrin beta chain, non-erythrocytic 2

1

0

High-throughput

0.458

High

193279

SOCS1
Suppressor of cytokine signaling 1

1

0

Small-scale

0.458

High

293722

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.458

High

315610

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.458

High

342193

BRD1
Bromodomain-containing protein 1

1

0

High-throughput

0.458

High

588758

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

634455

LMNB1
Lamin-B1

1

0

High-throughput

0.458

High

643855

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

0

High-throughput

0.458

High

664748

CCND1
G1/S-specific cyclin-D1

1

0

Small-scale

0.458

High

695523

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

799897

COIL
Coilin

1

0

High-throughput

0.458

High

830781

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

980786

H2B1C
Histone H2B type 1-C/E/F/G/I

1

0

High-throughput

0.458

High

1033684

PO5F1
POU domain, class 5, transcription factor 1

1

0

High-throughput

0.458

High

1146371

CL16A
Protein CLEC16A

1

0

High-throughput

0.458

High

1146378

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

1146379

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

1146386

AKAP1
A-kinase anchor protein 1, mitochondrial

1

0

High-throughput

0.458

High

1146393

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

1146395

CI072
Guanine nucleotide exchange factor C9orf72

1

0

High-throughput

0.458

High

1146396

CIC
Protein capicua homolog

1

0

High-throughput

0.458

High

1146399

DERL1
Derlin-1

1

0

High-throughput

0.458

High

1146403

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1146405

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

1146409

XPO7
Exportin-7

1

0

High-throughput

0.458

High

1146414

ZN330
Zinc finger protein 330

1

0

High-throughput

0.458

High

943946

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

1

High-throughput

0.445

High

1146401

Q9H4D1
Receptor-interacting serine/threonine-protein kinase 4

1

1

High-throughput

0.437

High

1146385

LIPH
Lipase member H

3

0

High-throughput

0.347

High

70216

CRTP1
Cysteine-rich tail protein 1

2

0

High-throughput

0.316

High

956056

SPCS3
Signal peptidase complex subunit 3

2

0

High-throughput

0.313

High

706129

S10A2
Protein S100-A2

1

0

High-throughput

0.279

Low

1101494

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

0

High-throughput

0.279

Low

1146377

LCN8
Epididymal-specific lipocalin-8

1

0

High-throughput

0.279

Low

1146384

ITLN1
Intelectin-1

1

0

High-throughput

0.279

Low

1146391

FWCH2
FLYWCH family member 2

1

0

High-throughput

0.279

Low

1146394

COX42
Cytochrome c oxidase subunit 4 isoform 2, mitochondrial

1

0

High-throughput

0.279

Low

1146410

CPSF3
Cleavage and polyadenylation specificity factor subunit 3

1

0

High-throughput

0.279

Low

411974

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

768255

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

1146404

S39A2
Zinc transporter ZIP2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025