Protein: PTGDS
Prostaglandin-H2 D-isomerase (EC 5.3.99.2) (Beta-trace protein) (Cerebrin-28) (Glutathione-independent PGD synthase) (Lipocalin-type prostaglandin-D synthase) (L-PGDS) (Prostaglandin-D2 synthase) (PGD2 synthase) (PGDS) (PGDS2)

Gene: PTGDS
Organism: Homo sapiens
Interactions: 35
UniProt ID: P41222

Gene Ontology (top 5):
GO:0001516 - prostaglandin biosynthetic process
GO:0004667 - prostaglandin-D synthase activity
GO:0005501 - retinoid binding
GO:0005504 - fatty acid binding
GO:0005576 - extracellular region

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

389651

A1AG1
Alpha-1-acid glycoprotein 1

2

1

High-throughput

0.811

High

833490

PTGDS
Prostaglandin-H2 D-isomerase

1

5

Small-scale

0.710

High

362909

EGFR
Epidermal growth factor receptor

2

4

Small-scale

0.608

High

70134

CRTP1
Cysteine-rich tail protein 1

2

0

High-throughput

0.580

High

833498

PD2R
Prostaglandin D2 receptor

1

2

Small-scale

0.578

High

461236

HS90A
Heat shock protein HSP 90-alpha

1

0

Small-scale

0.554

High

833503

GGA3
ADP-ribosylation factor-binding protein GGA3

1

0

Small-scale

0.554

High

833504

UBQL2
Ubiquilin-2

2

4

High-throughput

0.553

High

458314

ADRB2
Beta-2 adrenergic receptor

1

1

High-throughput

0.541

High

462849

LAMB1
Laminin subunit beta-1

1

1

High-throughput

0.536

High

833497

KR107
Keratin-associated protein 10-7

1

2

High-throughput

0.523

High

728081

AKT1
RAC-alpha serine/threonine-protein kinase

1

0

High-throughput

0.518

High

833506

SHLB1
Endophilin-B1

1

1

High-throughput

0.515

High

833499

PIGH
Phosphatidylinositol N-acetylglucosaminyltransferase subunit H

1

0

High-throughput

0.513

High

833500

RN183
E3 ubiquitin-protein ligase RNF183

1

0

High-throughput

0.513

High

561931

LAMP2
Lysosome-associated membrane glycoprotein 2

1

0

High-throughput

0.493

High

833491

HD
Huntingtin

1

0

High-throughput

0.493

High

407793

SHBG
Sex hormone-binding globulin

1

5

Small-scale

0.481

High

833492

CHIO
Beta-chimaerin

1

1

High-throughput

0.470

High

457057

CAN1
Calpain-1 catalytic subunit

1

0

Small-scale

0.460

High

463917

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

3

High-throughput

0.457

High

833496

KR103
Keratin-associated protein 10-3

1

3

High-throughput

0.439

High

105494

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

833493

ATX1
Ataxin-1

2

0

High-throughput

0.323

High

833495

KR123
Keratin-associated protein 12-3

2

0

High-throughput

0.316

High

833502

CAR10
Caspase recruitment domain-containing protein 10

2

0

High-throughput

0.316

High

732459

ARRB2
Beta-arrestin-2

1

0

Small-scale

0.299

High

338232

G6PE
GDH/6PGL endoplasmic bifunctional protein [Includes: Hexose-6-phosphate dehydrogenase

1

0

High-throughput

0.279

Low

833501

ZN747
Zinc finger protein 747

1

0

High-throughput

0.279

Low

833494

CASP6
Caspase-6

1

0

High-throughput

0.268

Low

139689

CAC1A
Voltage-dependent P/Q-type calcium channel subunit alpha-1A

1

0

High-throughput

0.265

Low

827340

MLH1
DNA mismatch repair protein Mlh1

1

0

Small-scale

0.265

Low

188569

BCAT2
Branched-chain-amino-acid aminotransferase, mitochondrial

1

0

High-throughput

0.251

Low

833505

PLAT4
Phospholipase A and acyltransferase 4

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025