Protein: SIGL5
Sialic acid-binding Ig-like lectin 5 (Siglec-5) (CD33 antigen-like 2) (Obesity-binding protein 2) (OB-BP2) (OB-binding protein 2) (CD antigen CD170)

Gene: SIGL5, SIGLEC5
Organism: Homo sapiens
Interactions: 27
UniProt ID: O15389

Gene Ontology (top 5):
GO:0005886 - plasma membrane
GO:0007155 - cell adhesion
GO:0030246 - carbohydrate binding
GO:0030667 - secretory granule membrane
GO:0033691 - sialic acid binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

188605

LAT2
Large neutral amino acids transporter small subunit 2

2

6

High-throughput

0.783

High

188604

KLHL8
Kelch-like protein 8

2

5

High-throughput

0.726

High

126271

TLR4
Toll-like receptor 4

1

20

Small-scale

0.681

High

188582

TLR3
Toll-like receptor 3

1

20

Small-scale

0.618

High

188584

TLR5
Toll-like receptor 5

1

20

Small-scale

0.618

High

188585

TLR2
Toll-like receptor 2

1

20

Small-scale

0.618

High

188592

TLR1
Toll-like receptor 1

1

20

Small-scale

0.618

High

188598

TLR10
Toll-like receptor 10

1

20

Small-scale

0.618

High

188600

TLR9
Toll-like receptor 9

1

20

Small-scale

0.618

High

188601

TLR8
Toll-like receptor 8

1

20

Small-scale

0.618

High

188603

TLR7
Toll-like receptor 7

1

20

Small-scale

0.618

High

188607

TLR6
Toll-like receptor 6

1

20

Small-scale

0.618

High

188591

VAC14
Protein VAC14 homolog

3

9

High-throughput

0.616

High

188589

PTN11
Tyrosine-protein phosphatase non-receptor type 11

3

20

Small-scale

0.609

High

188594

PCH2
Pachytene checkpoint protein 2 homolog

2

5

High-throughput

0.590

High

188593

CIP4
Cdc42-interacting protein 4

2

7

High-throughput

0.574

High

188599

SNAB
Beta-soluble NSF attachment protein

2

1

High-throughput

0.553

High

188590

LG3BP
Galectin-3-binding protein

1

15

Small-scale

0.501

High

188597

INT4
Integrator complex subunit 4

1

1

High-throughput

0.489

High

188602

UFSP2
Ufm1-specific protease 2

1

1

High-throughput

0.489

High

188606

GPN3
GPN-loop GTPase 3

1

1

High-throughput

0.489

High

188588

LEP
Leptin

1

2

Small-scale

0.481

High

188583

TYOBP
TYRO protein tyrosine kinase-binding protein

1

1

Small-scale

0.479

High

188587

PTN6
Tyrosine-protein phosphatase non-receptor type 6

1

20

Small-scale

0.479

High

188586

SH21A
SH2 domain-containing protein 1A

1

20

Small-scale

0.437

High

188595

EFNMT
eEF1A lysine and N-terminal methyltransferase

2

0

High-throughput

0.328

High

188596

PHOP2
Pyridoxal phosphate phosphatase PHOSPHO2

2

0

High-throughput

0.328

High


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Last updated: 11Aug2025