Protein: DENR
Translation machinery-associated protein 22 (Density-regulated protein homolog)

Gene: DENR, TMA22
Organism: Saccharomyces cerevisiae S288C
Interactions: 35
UniProt ID: P47089

Gene Ontology (top 5):
GO:0000184 - nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0001731 - formation of translation preinitiation complex
GO:0002188 - translation reinitiation
GO:0003723 - RNA binding
GO:0003743 - translation initiation factor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

865248

TMA20
Translation machinery-associated protein 20

5

2

Small-scale

0.922

High

524415

HSP71
Heat shock protein SSA1

2

1

High-throughput

0.571

High

792127

GBLP
Small ribosomal subunit protein RACK1

2

0

High-throughput

0.563

High

527058

HSP72
Heat shock protein SSA2

2

1

High-throughput

0.552

High

722061

XPO1
Exportin-1

1

2

High-throughput

0.536

High

865246

BRE5
UBP3-associated protein BRE5

1

0

High-throughput

0.513

High

865249

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

0

High-throughput

0.513

High

437935

KAPC
cAMP-dependent protein kinase type 3

1

1

High-throughput

0.501

High

441183

KAPA
cAMP-dependent protein kinase type 1

1

1

High-throughput

0.501

High

828611

YAP4
AP-1-like transcription factor YAP4

1

0

High-throughput

0.493

High

599378

FUS3
Mitogen-activated protein kinase FUS3

1

0

High-throughput

0.480

High

416259

SYDC
Aspartate--tRNA ligase, cytoplasmic

1

2

High-throughput

0.479

High

581880

SYKC
Lysine--tRNA ligase, cytoplasmic

1

2

High-throughput

0.479

High

802569

SYNC
Asparagine--tRNA ligase, cytoplasmic

1

2

High-throughput

0.479

High

709854

BMH1
Protein BMH1

1

0

High-throughput

0.458

High

750106

MRT4
Ribosome assembly factor MRT4

1

0

Small-scale

0.458

High

795435

ATG8
Autophagy-related protein 8

1

0

High-throughput

0.458

High

802653

YHI0
Putative proline--tRNA ligase YHR020W

1

0

High-throughput

0.458

High

807195

IF1A
Eukaryotic translation initiation factor 1A

1

0

High-throughput

0.458

High

865245

EIF2A
Eukaryotic translation initiation factor 2A

1

0

High-throughput

0.458

High

850073

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

1

High-throughput

0.437

High

545411

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.426

High

865251

SMT3
Ubiquitin-like protein SMT3

1

0

High-throughput

0.288

High

758011

PXA2
Peroxisomal long-chain fatty acid import protein 1

1

0

High-throughput

0.282

High

753457

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.279

Low

94571

STE2
Pheromone alpha factor receptor

1

0

High-throughput

0.251

Low

679836

CDC48
Cell division control protein 48

1

0

High-throughput

0.249

Low

694585

SPT5
Transcription elongation factor SPT5

1

0

High-throughput

0.249

Low

707519

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

812450

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

826628

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

865247

SAM50
Sorting assembly machinery 50 kDa subunit

1

0

High-throughput

0.249

Low

865250

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.249

Low

670883

SIS1
Protein SIS1

1

0

High-throughput

0.232

Low

747455

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025