Protein: STE2
Pheromone alpha factor receptor

Gene: STE2
Organism: Saccharomyces cerevisiae S288C
Interactions: 82
UniProt ID: D6VTK4

Gene Ontology (top 5):
GO:0000750 - pheromone-dependent signal transduction involved in conjugation with cellular fusion
GO:0000755 - cytogamy
GO:0004932 - mating-type factor pheromone receptor activity
GO:0004934 - mating-type alpha-factor pheromone receptor activity
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

94517

STE2
Pheromone alpha factor receptor

12

1

Small-scale

0.977

High

94526

GPA1
Guanine nucleotide-binding protein alpha-1 subunit

4

0

Small-scale

0.840

High

94523

MFAL1
Mating factor alpha-1

2

1

Small-scale

0.768

High

94545

MFAL2
Mating factor alpha-2

1

1

Small-scale

0.575

High

94530

GBB
Guanine nucleotide-binding protein subunit beta

2

0

Small-scale

0.559

High

94524

STE3
Pheromone a factor receptor

1

0

Small-scale

0.513

High

94568

ROG3
Protein ROG3

1

1

Small-scale

0.501

High

94582

ROD1
Protein ROD1

1

1

Small-scale

0.501

High

94596

LDB19
Protein LDB19

1

0

Small-scale

0.480

High

94518

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

1

0

High-throughput

0.460

High

94520

KPYK1
Pyruvate kinase 1

1

0

High-throughput

0.460

High

94521

PGK
Phosphoglycerate kinase

1

0

High-throughput

0.460

High

94529

NCPR
NADPH--cytochrome P450 reductase

1

0

High-throughput

0.460

High

94532

ARF2
ADP-ribosylation factor 2

1

0

High-throughput

0.460

High

94538

KIN82
Serine/threonine-protein kinase KIN82

1

0

High-throughput

0.460

High

94555

NCB5R
NADH-cytochrome b5 reductase 1

1

0

High-throughput

0.460

High

94561

SSB2
Ribosome-associated molecular chaperone SSB2

1

0

High-throughput

0.460

High

94567

ALR2
Magnesium transporter ALR2

1

0

High-throughput

0.460

High

94574

MLC1
Myosin light chain 1

1

0

High-throughput

0.460

High

94585

EFR3
Protein EFR3

1

0

High-throughput

0.460

High

94594

GET3
ATPase GET3

1

0

High-throughput

0.460

High

94533

PMA2
Plasma membrane ATPase 2

1

0

High-throughput

0.458

High

94556

KEL1
Kelch repeat-containing protein 1

1

0

Small-scale

0.458

High

94576

TNA1
High-affinity nicotinic acid transporter

1

0

High-throughput

0.458

High

94586

GAS3
Probable 1,3-beta-glucanosyltransferase GAS3

1

0

High-throughput

0.458

High

94588

HBT1
Protein HBT1

1

0

High-throughput

0.458

High

94587

CTK1
CTD kinase subunit alpha

1

1

High-throughput

0.439

High

94549

SEC6
Exocyst complex component SEC6

1

0

High-throughput

0.282

High

94519

CDK1
Cyclin-dependent kinase 1

1

0

Small-scale

0.261

Low

94522

PMG1
Phosphoglycerate mutase 1

1

0

High-throughput

0.251

Low

94525

DYR
Dihydrofolate reductase

1

0

High-throughput

0.251

Low

94527

RPA1
DNA-directed RNA polymerase I subunit RPA190

1

0

High-throughput

0.251

Low

94528

ABP1
Actin-binding protein

1

0

High-throughput

0.251

Low

94531

IRA1
Inhibitory regulator protein IRA1

1

0

High-throughput

0.251

Low

94535

SIN3
Transcriptional regulatory protein SIN3

1

0

High-throughput

0.251

Low

94536

TRX2
Thioredoxin-2

1

0

High-throughput

0.251

Low

94537

ERG4
Delta(24(24(1)))-sterol reductase ERG4

1

0

High-throughput

0.251

Low

94539

SPB1
27S pre-rRNA

1

0

High-throughput

0.251

Low

94540

TAH1
TPR repeat-containing protein associated with Hsp90

1

0

High-throughput

0.251

Low

94541

CDC15
Cell division control protein 15

1

0

High-throughput

0.251

Low

94543

BEM1
Bud emergence protein 1

1

0

High-throughput

0.251

Low

94546

EF1B
Elongation factor 1-beta

1

0

High-throughput

0.251

Low

94547

ZUO1
Zuotin

1

0

High-throughput

0.251

Low

94548

HSP7F
Heat shock protein homolog SSE1

1

0

High-throughput

0.251

Low

94550

IF4B
Eukaryotic translation initiation factor 4B

1

0

High-throughput

0.251

Low

94551

HES1
Oxysterol-binding protein homolog 5

1

0

High-throughput

0.251

Low

94552

ANM1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.251

Low

94553

PPS1
Dual specificity protein phosphatase PPS1

1

0

High-throughput

0.251

Low

94554

UBX7
UBX domain-containing protein 7

1

0

High-throughput

0.251

Low

94557

NACA
Nascent polypeptide-associated complex subunit alpha

1

0

High-throughput

0.251

Low

94559

RV167
Reduced viability upon starvation protein 167

1

0

High-throughput

0.251

Low

94560

HAT2
Histone acetyltransferase type B subunit 2

1

0

High-throughput

0.251

Low

94563

RL13B
Large ribosomal subunit protein eL13B

1

0

High-throughput

0.251

Low

94565

IMA5
Oligo-1,6-glucosidase IMA5

1

0

High-throughput

0.251

Low

94566

VATH
V-type proton ATPase subunit H

1

0

High-throughput

0.251

Low

94569

SAC3
Nuclear mRNA export protein SAC3

1

0

High-throughput

0.251

Low

94570

VTC4
Vacuolar transporter chaperone complex subunit 4

1

0

High-throughput

0.251

Low

94571

DENR
Translation machinery-associated protein 22

1

0

High-throughput

0.251

Low

94572

CENPK
Inner kinetochore subunit MCM22

1

0

High-throughput

0.251

Low

94573

SUT1
Sterol uptake protein 1

1

0

High-throughput

0.251

Low

94575

LSB1
LAS seventeen-binding protein 1

1

0

High-throughput

0.251

Low

94577

PPID
Peptidyl-prolyl cis-trans isomerase CPR6

1

0

High-throughput

0.251

Low

94578

CTU2
Cytoplasmic tRNA 2-thiolation protein 2

1

0

High-throughput

0.251

Low

94580

PTA1
Pre-tRNA-processing protein PTA1

1

0

High-throughput

0.251

Low

94581

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

0

High-throughput

0.251

Low

94583

YM8M
Uncharacterized transporter YMR279C

1

0

High-throughput

0.251

Low

94584

SCS7
Ceramide very long chain fatty acid hydroxylase SCS7

1

0

High-throughput

0.251

Low

94589

SGT1
Protein SGT1

1

0

High-throughput

0.251

Low

94591

ALE1
Lysophospholipid acyltransferase

1

0

High-throughput

0.251

Low

94592

GUP2
Membrane-bound O-acyltransferase GUP2

1

0

High-throughput

0.251

Low

94593

CDC53
Cell division control protein 53

1

0

High-throughput

0.251

Low

94595

AHA1
Hsp90 co-chaperone AHA1

1

0

High-throughput

0.251

Low

94597

DUF1
DUB-associated factor 1

1

0

High-throughput

0.251

Low

94534

MCK1
Protein kinase MCK1

1

0

High-throughput

0.249

Low

94542

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

94544

ACBP
Acyl-CoA-binding protein

1

0

High-throughput

0.249

Low

94558

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

94562

PPN2
Zinc-dependent endopolyphosphatase

1

0

High-throughput

0.249

Low

94564

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

94579

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.249

Low

94590

SGO1
Shugoshin

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025