Protein: SIX2
Homeobox protein SIX2 (Sine oculis homeobox homolog 2)

Gene: SIX2
Organism: Homo sapiens
Interactions: 30
UniProt ID: Q9NPC8

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001822 - kidney development

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1304296

EYA1
Eyes absent homolog 1

3

20

High-throughput

0.871

High

318733

EYA4
Eyes absent homolog 4

3

20

High-throughput

0.861

High

118611

EYA2
Eyes absent homolog 2

2

20

High-throughput

0.811

High

1304309

EYA3
Eyes absent homolog 3

2

20

High-throughput

0.811

High

980881

TLE3
Transducin-like enhancer protein 3

4

20

High-throughput

0.698

High

208863

CHM2A
Charged multivesicular body protein 2a

2

2

High-throughput

0.628

High

257706

ANR17
Ankyrin repeat domain-containing protein 17

2

3

High-throughput

0.628

High

1060935

IMB1
Importin subunit beta-1

2

1

High-throughput

0.628

High

1102069

ERC6L
DNA excision repair protein ERCC-6-like

2

14

High-throughput

0.628

High

993614

TLE5
TLE family member 5

2

20

High-throughput

0.606

High

1232239

CLIP4
CAP-Gly domain-containing linker protein 4

2

1

High-throughput

0.606

High

1068507

KPCD1
Serine/threonine-protein kinase D1

2

0

High-throughput

0.602

High

1311879

PSMG3
Proteasome assembly chaperone 3

2

0

High-throughput

0.602

High

92588

E9PLN6
Eyes absent homolog

1

20

High-throughput

0.575

High

1219854

ANKH1
Ankyrin repeat and KH domain-containing protein 1

2

3

High-throughput

0.574

High

1336680

CHM1A
Charged multivesicular body protein 1a

2

2

High-throughput

0.574

High

1342608

CHMP3
Charged multivesicular body protein 3

2

2

High-throughput

0.574

High

790886

CDN2A
Cyclin-dependent kinase inhibitor 2A

1

13

High-throughput

0.541

High

1326705

PIP30
PSME3-interacting protein

1

0

High-throughput

0.513

High

1342610

SP16H
FACT complex subunit SPT16

1

0

High-throughput

0.513

High

978904

TF65
Transcription factor p65

1

6

Small-scale

0.506

High

395839

A4
Amyloid-beta precursor protein

1

5

High-throughput

0.501

High

1183132

MARK2
Serine/threonine-protein kinase MARK2

1

2

High-throughput

0.489

High

1342609

CRBG1
Beta/gamma crystallin domain-containing protein 1

1

3

High-throughput

0.489

High

917974

H4
Histone H4

1

2

High-throughput

0.479

High

964529

RELB
Transcription factor RelB

1

6

Small-scale

0.479

High

980654

TLE1
Transducin-like enhancer protein 1

1

20

High-throughput

0.479

High

1132994

Q5T3G3
TLE family member 1, transcriptional corepressor

1

20

High-throughput

0.445

High

1191309

BN3D2
RNA 5'-monophosphate methyltransferase

2

0

High-throughput

0.328

High

1223448

THNS1
Threonine synthase-like 1

2

0

High-throughput

0.328

High


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Last updated: 15 Jul 2024