Protein: DAM1
DASH complex subunit DAM1 (DUO1 and MPS1-interacting protein 1) (Kinetochore assembly protein DAM1) (Outer kinetochore protein DAM1)

Gene: DAM1
Organism: Saccharomyces cerevisiae S288C
Interactions: 70
UniProt ID: P53267

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0008017 - microtubule binding
GO:0008608 - attachment of spindle microtubules to kinetochore
GO:0031116 - positive regulation of microtubule polymerization
GO:0042729 - DASH complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

917904

DUO1
DASH complex subunit DUO1

14

0

Small-scale

0.933

High

919110

DAD1
DASH complex subunit DAD1

11

0

Small-scale

0.929

High

781911

SPC34
DASH complex subunit SPC34

12

0

Small-scale

0.928

High

919103

SPC19
DASH complex subunit SPC19

6

0

Small-scale

0.896

High

782588

DAD2
DASH complex subunit DAD2

4

0

Small-scale

0.845

High

808649

AURK
Aurora kinase

7

1

Small-scale

0.749

High

824857

NDC80
Kinetochore protein NDC80

11

0

Small-scale

0.725

High

826690

DSN1
Kinetochore-associated protein DSN1

8

0

Small-scale

0.712

High

776701

ASK1
DASH complex subunit ASK1

7

0

Small-scale

0.707

High

919093

DAM1
DASH complex subunit DAM1

4

0

Small-scale

0.669

High

919100

HSK3
DASH complex subunit HSK3

5

0

Small-scale

0.667

High

919099

DAD4
DASH complex subunit DAD4

4

0

Small-scale

0.653

High

797344

INCE
Inner centromere protein SLI15

3

0

Small-scale

0.639

High

919106

ATG17
Autophagy-related protein 17

3

0

Small-scale

0.630

High

816967

BIM1
Protein BIM1

2

0

Small-scale

0.616

High

919098

DAD3
DASH complex subunit DAD3

3

0

Small-scale

0.614

High

919101

CENPP
Inner kinetochore subunit CTF19

2

0

Small-scale

0.583

High

919107

SP382
Pre-mRNA-splicing factor SPP382

2

0

High-throughput

0.582

High

755275

NUF2
Kinetochore protein NUF2

2

0

Small-scale

0.577

High

734706

IMB3
Importin subunit beta-3

2

0

Small-scale

0.576

High

919111

CENPH
Inner kinetochore subunit MCM16

2

0

Small-scale

0.565

High

858385

STU2
Protein STU2

2

0

Small-scale

0.551

High

919094

RTS3
Protein phosphatase type 2A regulatory subunit RTS3

1

0

High-throughput

0.518

High

738763

CBF3A
Centromere DNA-binding protein complex CBF3 subunit A

1

0

Small-scale

0.513

High

919095

CENPQ
Inner kinetochore subunit OKP1

1

0

Small-scale

0.513

High

864881

MAD3
Spindle assembly checkpoint component MAD3

1

1

Small-scale

0.479

High

797897

CENPU
Inner kinetochore subunit AME1

1

0

High-throughput

0.458

High

807022

CENPN
Inner kinetochore subunit CHL4

1

0

Small-scale

0.458

High

829784

MAD1
Spindle assembly checkpoint component MAD1

1

0

Small-scale

0.458

High

850688

CENPT
Inner kinetochore subunit CNN1

1

0

Small-scale

0.458

High

865900

BIR1
Chromosomal passenger complex protein BIR1

1

0

Small-scale

0.458

High

866207

CENPK
Inner kinetochore subunit MCM22

1

0

Small-scale

0.458

High

919102

FIN1
Filament protein FIN1

1

0

Small-scale

0.458

High

919105

SPC24
Kinetochore protein SPC24

1

0

Small-scale

0.458

High

585987

CSK21
Casein kinase II subunit alpha

1

1

Small-scale

0.457

High

622987

CSK22
Casein kinase II subunit alpha'

1

1

Small-scale

0.457

High

672435

STE50
Protein STE50

1

0

Small-scale

0.438

High

709890

BMH1
Protein BMH1

1

0

Small-scale

0.438

High

738068

MKK2
MAP kinase kinase MKK2/SSP33

1

0

Small-scale

0.438

High

795804

SHE1
Mitotic spindle-associated protein SHE1

1

0

Small-scale

0.438

High

835543

BUD6
Bud site selection protein 6

1

0

Small-scale

0.438

High

919108

ADY3
Accumulates dyads protein 3

1

0

Small-scale

0.438

High

919112

NOT5
General negative regulator of transcription subunit 5

1

0

Small-scale

0.438

High

835513

BUB1
Spindle assembly checkpoint serine/threonine-protein kinase BUB1

1

2

Small-scale

0.437

High

527267

HSP72
Heat shock protein SSA2

1

0

High-throughput

0.426

High

797118

CENPL
Inner kinetochore subunit IML3

1

0

High-throughput

0.426

High

919097

MPS1
Serine/threonine-protein kinase MPS1

4

0

Small-scale

0.357

High

779295

CENPA
Histone H3-like centromeric protein CSE4

2

0

Small-scale

0.320

High

917776

KXD1
Biogenesis of lysosome-related organelles complex 1 subunit KXD1

2

0

Small-scale

0.317

High

830011

LYS14
Lysine biosynthesis regulatory protein LYS14

1

0

High-throughput

0.282

High

864667

SNX4
Sorting nexin-4

1

0

Small-scale

0.282

High

763782

CBF3C
Centromere DNA-binding protein complex CBF3 subunit C

1

0

Small-scale

0.279

Low

805560

SET1
Histone-lysine N-methyltransferase, H3 lysine-4 specific

1

0

Small-scale

0.269

Low

441387

KAPB
cAMP-dependent protein kinase type 2

1

0

Small-scale

0.261

Low

602013

CBF1
Centromere-binding protein 1

1

0

Small-scale

0.261

Low

381187

H2B1
Histone H2B.1

1

0

Small-scale

0.249

Low

419469

H2A1
Histone H2A.1

1

0

Small-scale

0.249

Low

707738

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

829980

CBF3B
Centromere DNA-binding protein complex CBF3 subunit B

1

0

Small-scale

0.249

Low

818323

LCP5
U3 small nucleolar ribonucleoprotein protein LCP5

1

0

Small-scale

0.238

Low

818570

COG3
Conserved oligomeric Golgi complex subunit 3

1

0

Small-scale

0.238

Low

823491

NUP82
Nucleoporin NUP82

1

0

Small-scale

0.238

Low

867874

MED21
Mediator of RNA polymerase II transcription subunit 21

1

0

Small-scale

0.238

Low

893106

KEL2
Kelch repeat-containing protein 2

1

0

Small-scale

0.238

Low

919096

SPO1
Putative meiotic phospholipase SPO1

1

0

Small-scale

0.238

Low

919104

ECM11
Protein ECM11

1

0

Small-scale

0.238

Low

919109

YAP7
AP-1-like transcription factor YAP7

1

0

Small-scale

0.238

Low

810998

TCPD
T-complex protein 1 subunit delta

1

0

High-throughput

0.232

Low

919113

CENPW
Inner kinetochore subunit WIP1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025