Protein: PSH1
RING finger protein PSH1 (POB3/SPT16 histone-associated protein 1)

Gene: PSH1
Organism: Saccharomyces cerevisiae S288C
Interactions: 76
UniProt ID: Q12161

Gene Ontology (top 5):
GO:0000775 - chromosome, centromeric region
GO:0004842 - ubiquitin-protein transferase activity
GO:0005634 - nucleus
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0008270 - zinc ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

779370

CENPA
Histone H3-like centromeric protein CSE4

11

7

Small-scale

0.758

High

382410

H4
Histone H4

9

5

Small-scale

0.751

High

381307

H2B1
Histone H2B.1

6

7

Small-scale

0.724

High

381667

H2B2
Histone H2B.2

5

7

Small-scale

0.712

High

419905

H2A2
Histone H2A.2

5

6

Small-scale

0.706

High

963786

H3
Histone H3

5

7

Small-scale

0.706

High

739816

SPT16
FACT complex subunit SPT16

9

1

Small-scale

0.687

High

623037

CSK22
Casein kinase II subunit alpha'

3

6

Small-scale

0.664

High

1046958

POB3
FACT complex subunit POB3

6

1

Small-scale

0.659

High

419527

H2A1
Histone H2A.1

3

6

Small-scale

0.656

High

1084508

PSH1
RING finger protein PSH1

3

19

Small-scale

0.651

High

826928

DSN1
Kinetochore-associated protein DSN1

4

0

Small-scale

0.648

High

586050

CSK21
Casein kinase II subunit alpha

2

9

Small-scale

0.634

High

574824

UBC3
Ubiquitin-conjugating enzyme E2-34 kDa

1

20

Small-scale

0.618

High

701606

UBC8
Ubiquitin-conjugating enzyme E2-24 kDa

1

20

Small-scale

0.618

High

807030

CENPN
Inner kinetochore subunit CHL4

2

0

Small-scale

0.576

High

798577

HSM3
DNA mismatch repair protein HSM3

2

0

High-throughput

0.563

High

797911

CENPU
Inner kinetochore subunit AME1

2

0

Small-scale

0.559

High

757729

EDE1
EH domain-containing and endocytosis protein 1

2

5

High-throughput

0.558

High

1084510

CENPH
Inner kinetochore subunit MCM16

2

0

Small-scale

0.547

High

1084514

CENPI
Inner kinetochore subunit CTF3

2

0

Small-scale

0.547

High

642495

MCK1
Protein kinase MCK1

1

3

High-throughput

0.536

High

646098

KIN3
Serine/threonine-protein kinase KIN3

1

20

High-throughput

0.536

High

718963

CGS5
S-phase entry cyclin-5

1

3

High-throughput

0.536

High

735281

KNS1
Dual specificity protein kinase KNS1

1

11

High-throughput

0.536

High

748812

CGS6
S-phase entry cyclin-6

1

3

High-throughput

0.536

High

1064091

NOB1
20S-pre-rRNA D-site endonuclease NOB1

1

1

High-throughput

0.536

High

684924

DAL80
Nitrogen regulatory protein DAL80

1

1

High-throughput

0.508

High

403698

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

14

High-throughput

0.500

High

597305

BIP
Endoplasmic reticulum chaperone BiP

1

20

High-throughput

0.500

High

560634

KIN1
Serine/threonine protein kinase KIN1

1

3

High-throughput

0.489

High

560774

KIN2
Serine/threonine-protein kinase KIN2

1

3

High-throughput

0.489

High

678137

SYP1
Suppressor of yeast profilin deletion

1

2

High-throughput

0.489

High

866039

YMR1
Phosphoinositide 3-phosphatase

1

2

High-throughput

0.489

High

675267

PSB3
Proteasome subunit beta type-3

1

6

High-throughput

0.479

High

678759

PAT1
Deadenylation-dependent mRNA-decapping factor PAT1

1

2

Small-scale

0.479

High

708508

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

744939

SLA1
Actin cytoskeleton-regulatory complex protein SLA1

1

4

High-throughput

0.479

High

806838

RPN10
26S proteasome regulatory subunit RPN10

1

1

High-throughput

0.479

High

823059

ATAD2
ATPase histone chaperone YTA7

1

4

High-throughput

0.479

High

1024993

2ABA
Protein phosphatase PP2A regulatory subunit B

1

1

Small-scale

0.479

High

1038773

XRN2
5'-3' exoribonuclease 2

1

1

High-throughput

0.479

High

1084513

H2AZ
Histone H2A.Z

1

6

Small-scale

0.479

High

790236

GLYC
Serine hydroxymethyltransferase, cytosolic

1

2

High-throughput

0.470

High

534322

RPA1
DNA-directed RNA polymerase I subunit RPA190

1

0

High-throughput

0.458

High

763757

CENPC
Inner kinetochore subunit MIF2

1

0

Small-scale

0.458

High

764031

SPT10
Protein SPT10

1

0

High-throughput

0.458

High

797134

CENPL
Inner kinetochore subunit IML3

1

0

Small-scale

0.458

High

814098

MTW1
Kinetochore-associated protein MTW1

1

0

Small-scale

0.458

High

866080

NNF1
Kinetochore-associated protein NNF1

1

0

Small-scale

0.458

High

866216

CENPK
Inner kinetochore subunit MCM22

1

0

Small-scale

0.458

High

1038173

CENPP
Inner kinetochore subunit CTF19

1

0

Small-scale

0.458

High

1053953

NKP2
Inner kinetochore subunit NKP2

1

0

Small-scale

0.458

High

1084397

NSL1
Kinetochore-associated protein NSL1

1

0

Small-scale

0.458

High

1084511

NKP1
Inner kinetochore subunit NKP1

1

0

Small-scale

0.458

High

425157

OTC
Ornithine carbamoyltransferase

1

2

High-throughput

0.457

High

1062759

THI20
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI20

1

1

High-throughput

0.457

High

1065631

THI21
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI21

1

1

High-throughput

0.457

High

481811

HSP73
Heat shock protein SSA3

1

16

High-throughput

0.445

High

525515

HSP71
Heat shock protein SSA1

1

16

High-throughput

0.445

High

820097

SSB2
Ribosome-associated molecular chaperone SSB2

1

16

High-throughput

0.445

High

1084509

NPC1
NPC intracellular sterol transporter 1-related protein 1

1

1

Small-scale

0.439

High

807796

CSK2C
Casein kinase II subunit beta'

1

1

Small-scale

0.437

High

851031

CSK2B
Casein kinase II subunit beta

1

1

Small-scale

0.437

High

1084512

NOP58
Nucleolar protein 58

1

6

High-throughput

0.437

High

850701

CENPT
Inner kinetochore subunit CNN1

1

0

High-throughput

0.426

High

510902

HSP77
Import motor subunit, mitochondrial

1

20

High-throughput

0.407

High

752875

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.407

High

811067

TCPD
T-complex protein 1 subunit delta

1

11

High-throughput

0.407

High

919469

CENPQ
Inner kinetochore subunit OKP1

2

0

Small-scale

0.313

High

700206

GAC1
Serine/threonine-protein phosphatase 1 regulatory subunit GAC1

1

0

High-throughput

0.279

Low

825785

MAM33
Mitochondrial acidic protein MAM33

1

0

High-throughput

0.279

Low

803238

PHS
Putative pterin-4-alpha-carbinolamine dehydratase

1

0

High-throughput

0.265

Low

673271

LSB5
LAS seventeen-binding protein 5

1

0

High-throughput

0.249

Low

1056413

CENPO
Inner kinetochore subunit MCM21

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025