Protein: CENPH
Inner kinetochore subunit MCM16 (CENP-H homolog) (Constitutive centromere-associated network protein MCM16) (Minichromosome maintenance protein 16)

Gene: CENPH, MCM16
Organism: Saccharomyces cerevisiae S288C
Interactions: 70
UniProt ID: Q12262

Gene Ontology (top 5):
GO:0000776 - kinetochore
GO:0005634 - nucleus
GO:0007059 - chromosome segregation
GO:0008608 - attachment of spindle microtubules to kinetochore
GO:0034087 - establishment of mitotic sister chromatid cohesion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

866218

CENPK
Inner kinetochore subunit MCM22

12

0

Small-scale

0.727

High

1084687

CENPI
Inner kinetochore subunit CTF3

9

0

Small-scale

0.718

High

797912

CENPU
Inner kinetochore subunit AME1

6

0

Small-scale

0.696

High

919471

CENPQ
Inner kinetochore subunit OKP1

6

0

Small-scale

0.696

High

826937

DSN1
Kinetochore-associated protein DSN1

6

0

Small-scale

0.693

High

1056415

CENPO
Inner kinetochore subunit MCM21

5

0

Small-scale

0.684

High

1038174

CENPP
Inner kinetochore subunit CTF19

5

0

Small-scale

0.666

High

1084685

NKP1
Inner kinetochore subunit NKP1

4

0

Small-scale

0.658

High

814099

MTW1
Kinetochore-associated protein MTW1

4

0

Small-scale

0.653

High

807031

CENPN
Inner kinetochore subunit CHL4

4

0

Small-scale

0.649

High

850703

CENPT
Inner kinetochore subunit CNN1

3

0

Small-scale

0.638

High

797135

CENPL
Inner kinetochore subunit IML3

3

0

Small-scale

0.634

High

1053955

NKP2
Inner kinetochore subunit NKP2

3

0

Small-scale

0.630

High

826112

ULP2
Ubiquitin-like-specific protease 2

2

0

Small-scale

0.622

High

919111

DAM1
DASH complex subunit DAM1

2

0

Small-scale

0.565

High

866083

NNF1
Kinetochore-associated protein NNF1

2

0

Small-scale

0.547

High

1084398

NSL1
Kinetochore-associated protein NSL1

2

0

Small-scale

0.547

High

1084510

PSH1
RING finger protein PSH1

2

0

Small-scale

0.547

High

779372

CENPA
Histone H3-like centromeric protein CSE4

2

0

Small-scale

0.528

High

382413

H4
Histone H4

1

0

High-throughput

0.493

High

677861

RDS1
Regulator of drug sensitivity 1

1

0

High-throughput

0.486

High

395269

GCN4
General control transcription factor GCN4

1

0

High-throughput

0.460

High

466808

SWI5
Transcriptional factor SWI5

1

0

High-throughput

0.460

High

548249

BIK1
Nuclear fusion protein BIK1

1

0

High-throughput

0.460

High

639519

RE107
Recombination protein 107

1

0

High-throughput

0.460

High

738016

MEI5
Meiosis protein 5

1

0

High-throughput

0.460

High

747768

SMC1
Structural maintenance of chromosomes protein 1

1

0

High-throughput

0.460

High

749738

TYE7
Transcription factor TYE7

1

0

High-throughput

0.460

High

809068

POP2
Poly(A) ribonuclease POP2

1

0

High-throughput

0.460

High

817045

SPC25
Kinetochore protein SPC25

1

0

High-throughput

0.460

High

828623

YAP4
AP-1-like transcription factor YAP4

1

0

High-throughput

0.460

High

829796

MAD1
Spindle assembly checkpoint component MAD1

1

0

High-throughput

0.460

High

916735

PPP5
Serine/threonine-protein phosphatase T

1

0

High-throughput

0.460

High

999583

DAD4
DASH complex subunit DAD4

1

0

High-throughput

0.460

High

1027299

SLT2
Mitogen-activated protein kinase SLT2/MPK1

1

0

High-throughput

0.460

High

1046291

RPC10
DNA-directed RNA polymerase III subunit RPC10

1

0

High-throughput

0.460

High

1056302

HDA2
HDA1 complex subunit 2

1

0

High-throughput

0.460

High

1062221

YAP7
AP-1-like transcription factor YAP7

1

0

High-throughput

0.460

High

1084618

SIZ2
E3 SUMO-protein ligase SIZ2

1

0

High-throughput

0.460

High

708541

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

917926

YBP2
YAP1-binding protein 2

1

0

Small-scale

0.458

High

1084688

CENPW
Inner kinetochore subunit WIP1

1

0

Small-scale

0.458

High

742686

HSP7F
Heat shock protein homolog SSE1

1

1

High-throughput

0.445

High

486355

TBA1
Tubulin alpha-1 chain

1

0

High-throughput

0.426

High

525563

HSP71
Heat shock protein SSA1

1

0

High-throughput

0.426

High

546761

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.426

High

824887

NDC80
Kinetochore protein NDC80

1

0

High-throughput

0.426

High

917914

DUO1
DASH complex subunit DUO1

1

0

High-throughput

0.426

High

1084683

CENPH
Inner kinetochore subunit MCM16

1

0

High-throughput

0.426

High

598936

PFKA1
ATP-dependent 6-phosphofructokinase subunit alpha

1

1

High-throughput

0.407

High

599094

PFKA2
ATP-dependent 6-phosphofructokinase subunit beta

1

1

High-throughput

0.407

High

850312

FAR7
Factor arrest protein 7

2

0

High-throughput

0.319

High

752055

PRP18
Pre-mRNA-splicing factor 18

1

0

High-throughput

0.269

Low

1030059

ARG56
Protein ARG5,6, mitochondrial [Cleaved into: N-acetyl-gamma-glutamyl-phosphate reductase

1

0

High-throughput

0.269

Low

150196

THP2
THO complex subunit THP2

1

0

High-throughput

0.251

Low

154371

YO304
Uncharacterized protein YOR304C-A

1

0

High-throughput

0.251

Low

672475

STE50
Protein STE50

1

0

High-throughput

0.251

Low

735688

SMY1
Kinesin-related protein SMY1

1

0

High-throughput

0.251

Low

744798

LAA2
Clathrin adapter accessory protein LAA2

1

0

High-throughput

0.251

Low

806449

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

High-throughput

0.251

Low

809243

END3
Actin cytoskeleton-regulatory complex protein END3

1

0

High-throughput

0.251

Low

816707

VAB2
Biogenesis of lysosome-related organelles complex 1 subunit VAB2

1

0

High-throughput

0.251

Low

919279

YG3A
Uncharacterized protein YGR130C

1

0

High-throughput

0.251

Low

1084676

NYV1
Vacuolar v-SNARE NYV1

1

0

High-throughput

0.251

Low

1084684

CLF1
Pre-mRNA-splicing factor CLF1

1

0

High-throughput

0.251

Low

1084686

ATG11
Autophagy-related protein 11

1

0

High-throughput

0.251

Low

1084689

CENPX
Inner kinetochore subunit MHF2

1

0

Small-scale

0.249

Low

367151

ATPB
ATP synthase subunit beta, mitochondrial

1

0

High-throughput

0.232

Low

858150

SYEC
Glutamate--tRNA ligase, cytoplasmic

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025